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不同间充质干细胞及外泌体治疗宫腔粘连的研究进展 被引量:1
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作者 叶红娟 石丽雅 +1 位作者 全心馨 薛松果 《生殖医学杂志》 CAS 2023年第5期793-797,共5页
宫腔粘连(IUA)是一种子宫内膜损伤性疾病,严重影响育龄期妇女生殖健康,已成为子宫性不孕因素的首要病因。目前尚无有效的治愈IUA的方法。间充质干细胞(MSCs)治疗作为一种新的再生医学细胞治疗方法,主要通过归巢到损伤部位后分化为子宫... 宫腔粘连(IUA)是一种子宫内膜损伤性疾病,严重影响育龄期妇女生殖健康,已成为子宫性不孕因素的首要病因。目前尚无有效的治愈IUA的方法。间充质干细胞(MSCs)治疗作为一种新的再生医学细胞治疗方法,主要通过归巢到损伤部位后分化为子宫内膜细胞、调节宫腔免疫环境、抑制上皮间质转化、抗纤维化、调控子宫局部的MSCs增殖和迁移等作用,对子宫内膜再生和修复产生影响。MSCs旁分泌的外泌体主要通过促进细胞增殖、抑制细胞凋亡、抗炎和免疫调节功能、促进新生血管形成等作用修复子宫内膜。因此,本文针对IUA的研究现状、MSCs及外泌体对IUA的作用及机制的研究进展进行综述。 展开更多
关键词 间充质干细胞 外泌体 宫腔粘连
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基于直方图匹配与图像修复的图像风格化 被引量:1
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作者 叶红娟 彭宏京 杜振龙 《计算机工程与设计》 北大核心 2018年第10期3176-3180,3200,共6页
为增强现有的风格化效果,提出一种基于直方图匹配和图像修复的图像风格化处理方法。根据超像素分割算法对源图像和参考图像进行分块,将每块进行标记;根据定义的最佳匹配算法,即以块为单位的平均值、方差、色调及平滑度对比,找到源图像... 为增强现有的风格化效果,提出一种基于直方图匹配和图像修复的图像风格化处理方法。根据超像素分割算法对源图像和参考图像进行分块,将每块进行标记;根据定义的最佳匹配算法,即以块为单位的平均值、方差、色调及平滑度对比,找到源图像在参考图像中的最佳匹配块;通过直方图匹配,将参考图像的风格采用最佳匹配算法原则以块为单位转换到源图像中去;根据图像修复算法修复块与块的拼接处,减少输出图像的噪声。实验结果表明,该方法可以适应不同的风格化要求,保留图像本身内容,效果很好。 展开更多
关键词 基于实例的风格化 图像分割 最佳匹配 直方图匹配 图像修复
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ACOUSTIC LOCAL MODE AND TA BAND MODE VIBRATION FOR THE MIXED CRYSTALS Cd_(1-x)Mn_(x)Te
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作者 SHEN Xue-chu ye hong-juan +1 位作者 KANG Li-xue TAO Feng-xiang 《Chinese Physics Letters》 SCIE CAS 1985年第5期209-212,共4页
We report here the acoustic local mode and TA band mode for the lattice vibration of the mixed crystals Cd_(1-x)Mn_(x)Te as observed by very far infrared spectra.The occurence of the acoustic local mode and the weakly... We report here the acoustic local mode and TA band mode for the lattice vibration of the mixed crystals Cd_(1-x)Mn_(x)Te as observed by very far infrared spectra.The occurence of the acoustic local mode and the weakly optical activity of TA mode induced by crystalline-mixing are discussed in light of the defect lattice dynamics. 展开更多
关键词 dynamics. spectra. LATTICE
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Impact of Progesterone on Inhibins during Controlled Ovarian Stimulation
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作者 ye Jing Chen Qiu-Ju +5 位作者 He Wen Zhang Jie ye hong-juan Fu Yong-Lun Lyu Qi-Feng Kuang Yan-Ping 《Reproductive and Developmental Medicine》 CSCD 2017年第2期69-76,共8页
Background:To explore the impact of progesterone on inhibins during controlled ovarian stimulation in women with normal ovarian reserve and to compare cycle characteristics and pregnancy outcomes in subsequently froze... Background:To explore the impact of progesterone on inhibins during controlled ovarian stimulation in women with normal ovarian reserve and to compare cycle characteristics and pregnancy outcomes in subsequently frozen-thawed embryo transfer(FET)cycles.Methods:A total of 93 patients were randomly divided into two groups,study group(human menopausal gonadotropin[hMG]+medroxyprogesterone acetate[MPA])and control group(short protocol).Serum hormones were detected on day 3 before ovarian and day 10-12,the trigger day,and the day after trigger(approximately 10 h after trigger).Viable embryos were cryopreserved for later transfer in both protocols.Results:In the study group,inhibins signifcantly increased during ovarian stimulation,and the average inhibins level on the trigger day was signifcantly higher than the basal levels.Inhibin A level increased significantly to 2046.7±1280.5 ng/L after trigger 10 h.Serum inhibin B level slightly decreased at the time of trigger 10 h later compared with the trigger time but did not reach a significant difference.The number of oocytes retrieved in study group was similar to that in control(10.5±4.5 vs.9.0±5.2,P<0.05).No statistically significant differences were found in the clinical pregnancy rate(47.4%vs.52.2%,P<0.05),implantation rate(36.5%vs.36%),and live birth rate(43.4%vs.39.1%,P<0.05)between the two groups.Conclusions:The high level of progesterone did not affect the secretion in granulosa cells during the controlled ovarian stimulation.Therefore,sufficient oocytes/embryos can be obtained by hMG and MPA co-treatment in women undergoing in vitro fertilization/intracytoplasmic sperm injection treatments,with optimal pregnancy outcomes in FET cycles. 展开更多
关键词 Controlled Ovarian Stimulation INHIBINS PROGESTERONE
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