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上海市虹口区社区老人轻度认知障碍患病现状及影响因素分析 被引量:1
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作者 王鹏飞 刘馨雅 +4 位作者 杨婷婷 阮晔 孙双圆 杨颖华 王颖 《阿尔茨海默病及相关病杂志》 2023年第2期97-103,共7页
目的:据调查上海市虹口区社区老人的轻度认知障碍(MCI)患病现状,分析MCI的危险及保护因素,为MCI的早期发现与精准干预提供科学依据。方法:2020年12月~2021年8月期间,采用整群随机抽样抽取60岁及以上的上海市虹口区社区老人2500人,使用M... 目的:据调查上海市虹口区社区老人的轻度认知障碍(MCI)患病现状,分析MCI的危险及保护因素,为MCI的早期发现与精准干预提供科学依据。方法:2020年12月~2021年8月期间,采用整群随机抽样抽取60岁及以上的上海市虹口区社区老人2500人,使用MMSE量表判断MCI,并通过logistic回归分析MCI的影响因素。结果:上海市虹口区社区老人的MCI患病率为12.1%。高龄、子女见面频率低、抑郁、低躯体疼痛、失能为MCI患病危险因素,高文化程度、中等强度的体育锻炼、较高的生理功能和生理职能以及较好的总体健康为MCI患病保护因素。结论:上海市虹口区社区老人的MCI患病率较全国其他地区略低。子女提高对老人的关注、增强体育锻炼、加强对抑郁等心理健康问题的筛查与干预及生理功能干预有利于预防MCI。 展开更多
关键词 轻度认知障碍 患病率 影响因素
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Progress in the correlation between chronic insomnia disorder and cytokines
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作者 Juan Zhou Jun Zhao +1 位作者 Hongying Pan ye ruan 《Journal of Translational Neuroscience》 2022年第2期1-7,共7页
Chronic insomnia disorder(CID)is a relatively common clinical sleep disorder,which is es-sentially characterized by dissatisfaction with sleep due to frequent and persistent difficulties in falling asleep or maintaini... Chronic insomnia disorder(CID)is a relatively common clinical sleep disorder,which is es-sentially characterized by dissatisfaction with sleep due to frequent and persistent difficulties in falling asleep or maintaining sleep.The etiology and pathogenesis of CID are not fully understood.In the past decades,medical re-search has explored the interrelationship between cyto-kines(CKs)and sleep disorders,and this paper reviews the correlation between CID and inflammatory factors in the context of domestic and international research on the subject. 展开更多
关键词 chronic insomnia disorder(CID) cy-tokine(CK) interleukin(IL)-6 IL-8 IL-1β tumor necro-sis factor-α(TNF-α)
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Research progress on the relationship between proBDNF and alcohol dependence and its related cognitive impairment
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作者 Hongying Pan Lan Jiang +3 位作者 Le Zhang Tiantian Jiang Tiankai Jiang ye ruan 《Journal of Translational Neuroscience》 2022年第3期1-6,共6页
Brain-derived neurotrophic factor(BDNF)plays an important role in the growth,develop-ment,differentiation,injury,repair,survival and apoptosis of nerve cells.Precursor of BDNF(proBDNF)is an im-portant regulator of neu... Brain-derived neurotrophic factor(BDNF)plays an important role in the growth,develop-ment,differentiation,injury,repair,survival and apoptosis of nerve cells.Precursor of BDNF(proBDNF)is an im-portant regulator of neurodegeneration,long-term hippo-campal inhibition and synaptic plasticity.Alcohol depen-dence syndrome(ADS)is a group of chronic recurrent diseases with unknown etiology.Current studies believe that proBDNF plays an important role in the occurrence,development and outcome of ADS.Alcohol dependence patients,like other neurodegenerative diseases,will also have different degrees of cognitive impairment.This arti-cle reviews the research progress on the relationship be-tween BDNF,proBDNF,alcohol dependence and cogni-tive impairment. 展开更多
关键词 alcohol dependence syndrome(ADS) brain-derived neurotrophic factor(BDNF) precursor of BDNF(proBDNF) COGNITION
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Progress in the application of P300 in depression
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作者 Xi Zhang Tiankai Jiang +1 位作者 Yuhang Liang ye ruan 《Journal of Translational Neuroscience》 2022年第2期8-11,共4页
Depression is a common mental disor-der with low mood,loss of interest and pleasure as main symptoms.Because of depending on the subjective diag-nosis of psychiatrists,its diagnosis is no reliable objective basis.P300... Depression is a common mental disor-der with low mood,loss of interest and pleasure as main symptoms.Because of depending on the subjective diag-nosis of psychiatrists,its diagnosis is no reliable objective basis.P300 research findings can be used as an objective diagnostic indicator for patients.This paper mainly intro-duces the current research status of event-related poten-tials for depression and introduces the scientific research and clinical significance of P300 for depression. 展开更多
关键词 DEPRESSION event-related potential P300
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Research progress on benzodiazepines to treat alcohol withdrawal syndrome
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作者 Tiankai Jiang Yuhang Liang +3 位作者 Lan Jiang Yinhang Li Tiantian Jiang ye ruan 《Journal of Translational Neuroscience》 2022年第4期12-16,共5页
Alcohol withdrawal syndrome(AWS)refers to a series of symptoms and signs that chronic al-coholics experience when they suddenly stop drinking or reduce their drinking,usually 12 to 24 h later.These in-clude tremors,fa... Alcohol withdrawal syndrome(AWS)refers to a series of symptoms and signs that chronic al-coholics experience when they suddenly stop drinking or reduce their drinking,usually 12 to 24 h later.These in-clude tremors,fatigue,sweating,hyperreflexia,and gas-trointestinal symptoms.This article will analyze the drug treatment of this disease and make a brief review. 展开更多
关键词 alcohol withdrawal syndrome(AWS) benzodiazepine(BDZ) symptom-triggered regimens
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