玻璃体切割术后超声乳化联合人工晶状体植入术的屈光误差分析

目的:探讨玻璃体切割术后白内障患者Ⅱ期行白内障超声乳化抽吸联合人工晶状体(IOL)植入的屈光误差。方法:回顾性分析。选取既往行玻璃体切割术现发生白内障需行手术治疗的患者38例40眼。按既往玻璃体腔填充物分为2组,A组(22眼)为既往单纯行玻璃体切割组,B组(18眼)为既往行玻璃体切割联合惰性气体(C_(3)F_(8))填充组。另设置无玻璃体切割手术史现需行白内障超声乳化抽吸手术的正常对照组C组(20眼)。术前应用IOL Master 500测量眼轴长度(AL)、角膜曲率(K)、前房深度(ACD),角膜横径(W-W),带入Barrett UniversalⅡ公式计算IOL屈光度。A组、B组采用虹膜拉钩辅助的超声乳化抽吸联合IOL植入术,C组为单纯超声乳化抽吸联合IOL植入术。术中均无后囊膜破裂等并发症。术后3mo验光获得实测屈光度。比较3组的预测误差、绝对预测误差、绝对误差中位数。结果:三组间AL、K、植入IOL屈光度数均无差异(P>0.05)。A组、B组ACD均较C组显著加深(P<0.01)。三组间预测误差有差异(P=0.042),B组较C组有显著的远视漂移。绝对预测误差、绝对误差中位数在组间无差异。结论:单纯玻璃体切割术后Ⅱ期白内障超声乳化联合IOL植入,与正常对照组相比,术后屈光结果无显著差异;但在玻璃体切割联合惰性气体填充术后患者,Ⅱ期白内障超声乳化抽吸术后会产生远视漂移,在选择IOL时应避免欠矫,适当过矫。

Intracameral anti-VEGF injection for advanced neovascular glaucoma after vitrectomy with silicone oil tamponade

AIM: To evaluate the effect of intracameral injection of conbercept for the treatment of advanced neovascular glaucoma(NVG) after vitrectomy with silicone oil tamponade.METHODS: Conbercept 0.5 mg/0.05 m L was injected into the anterior chamber of 5 eyes, which had developed advanced NVG after vitrectomy with silicone oil tamponade. Then, trabeculectomy with mitomycin C and pan-retinal photocoagulation(PRP) or extra-PRP were conducted within 2 d. The follow-up time was 6 mo. Best-corrected visual acuity(BCVA), intraocular pressure(IOP), neovascularization of iris(NVI) were recorded before and after treatment.RESULTS: Within 2 d after injection, IOP control, and NVI regression were optimal for trabeculectomy. Hyphema occurred in one eye in the process of injection. But none of them present hyphema after trabeculectomy. At the end of follow-up time, all eyes had improved BCVA, well-controlled IOP, and completely regressed NVI. CONCLUSION: Intracameral injection of conbercept is safe and effective in the treatment of patients with advanced NVG after vitrectomy with silicone oil tamponade. Within 2 d after injection is the optimal time window for trabeculectomy, which can maximally reduce the risk of perioperative hyphema.