Dear Editor,Atrial fibrillation(AF)is one of the most common cardiac arrhythmias.Its prevalence increases significantly with age.It is well known that patients with AF are associated with an increased risk of stroke,1...Dear Editor,Atrial fibrillation(AF)is one of the most common cardiac arrhythmias.Its prevalence increases significantly with age.It is well known that patients with AF are associated with an increased risk of stroke,1 and AF is a great economic burden on the worldwide socioeconomic system.Previous studies have shown that electrical,contractile,and structural remodeling play key roles in the onset and maintenance of AF.2 Other possible pathogenesis mechanisms include calcium handling abnormalities,autonomic imbalance,and genetic factors.3 However,the exact molecular mechanism associated with AF remains unknown.展开更多
基金supported by the National Natural Science Foundation of China[81870288&81641017]the Nonprofit Central Research Institute Fund of the Chinese Academy of Medical Sciences[2019XK310001&2018TX31002&2017NL31001]the Tianjin Science and Technology Committee[18PTZWHZ00060].
文摘Dear Editor,Atrial fibrillation(AF)is one of the most common cardiac arrhythmias.Its prevalence increases significantly with age.It is well known that patients with AF are associated with an increased risk of stroke,1 and AF is a great economic burden on the worldwide socioeconomic system.Previous studies have shown that electrical,contractile,and structural remodeling play key roles in the onset and maintenance of AF.2 Other possible pathogenesis mechanisms include calcium handling abnormalities,autonomic imbalance,and genetic factors.3 However,the exact molecular mechanism associated with AF remains unknown.
