In order to improve the performance of UAV's autonomous maneuvering decision-making,this paper proposes a decision-making method based on situational continuity.The algorithm in this paper designs a situation eval...In order to improve the performance of UAV's autonomous maneuvering decision-making,this paper proposes a decision-making method based on situational continuity.The algorithm in this paper designs a situation evaluation function with strong guidance,then trains the Long Short-Term Memory(LSTM)under the framework of Deep Q Network(DQN)for air combat maneuvering decision-making.Considering the continuity between adjacent situations,the method takes multiple consecutive situations as one input of the neural network.To reflect the difference between adjacent situations,the method takes the difference of situation evaluation value as the reward of reinforcement learning.In different scenarios,the algorithm proposed in this paper is compared with the algorithm based on the Fully Neural Network(FNN)and the algorithm based on statistical principles respectively.The results show that,compared with the FNN algorithm,the algorithm proposed in this paper is more accurate and forwardlooking.Compared with the algorithm based on the statistical principles,the decision-making of the algorithm proposed in this paper is more efficient and its real-time performance is better.展开更多
BACKGROUND Myopia,as one of the common ocular diseases,often occurs in adolescence.In addition to the harm from itself,it may also lead to serious complications.Thus,prevention and control of myopia are attracting mor...BACKGROUND Myopia,as one of the common ocular diseases,often occurs in adolescence.In addition to the harm from itself,it may also lead to serious complications.Thus,prevention and control of myopia are attracting more and more attention.Previous research revealed that single-focal glasses and orthokeratology lenses(OK lenses)played an important part in slowing down myopia and preventing high myopia.AIM To compare the clinical effects of OK lenses and frame glasses against the increase of diopter in adolescent myopia and further explore the mechanism of the OK lens.METHODS Changes in diopter and axial length were collected among 70 adolescent myopia patients(124 eyes)wearing OK lenses for 1 year(group A)and 59 adolescent myopia patients(113 eyes)wearing frame glasses(group B).Refractive states of their retina were inspected through multispectral refraction topography.The obtained hyperopic defocus was analyzed for the mechanism of OK lenses on slowing down the increase of myopic diopter by delaying the increase of ocular axis length and reducing the near hyperopia defocus.RESULTS Teenagers in groups A and B were divided into low myopia(0 D--3.00 D)and moderate myopia(-3.25 D--6.00 D),without statistical differences among gender and age.After 1-year treatment,the increase of diopter and axis length and changes of retinal hyperopic defocus amount of group A were significantly less than those of group B.According to the multiple linear analysis,the retinal defocus in the upper,lower,nasal,and temporal directions had almost the same effect on the total defocus.The amount of peripheral retinal defocus(15°-53°)in group A was significantly lower than that in group B.CONCLUSION Multispectral refraction topography is progressive and instructive in clinical prevention and control of myopia.展开更多
Six core issues for vortex definition and identification concern with (1) the absolute strength,(2) the relative strength,(3) the rotational axis,(4) the vortex core center,(5) the vortex core size, and (6) the vortex...Six core issues for vortex definition and identification concern with (1) the absolute strength,(2) the relative strength,(3) the rotational axis,(4) the vortex core center,(5) the vortex core size, and (6) the vortex boundary (Liu C. 2019). However, most of the currently popular vortex identification methods, including the Q criterion, the criterion and the Acj criterion etc., are Eulerian local region-type vortex identification criteria and can only approximately identify the vortex boundary by somewhat arbitrary threshold. On the other hand, the existing Eulerian local line-type methods, which seek to extract line-type features such as vortex core line, are not entirely satisfactory since most of these methods are based on vorticity or pressure minimum that will fail in many cases. The key issue is the lack of a reasonable mathematical definition for vortex core center. To address this issue, a Liutex (previously named Rortex) based definition of vortex core center is proposed in this paper. The vortex core center, also called vortex rotation axis line here, is defined as a line where the Liutex magnitude gradient vector is aligned with the Liutex vector, which mathematically implies that the cross product of the Liutex magnitude gradient vector and the Liutex vector on the line is equal to zero. Based on this definition, a novel three-step method for extracting vortex rotation axis lines is presented. Two test cases, namely the Burgers vortex and hairpin vortices, are examined to justify the proposed method. The results demonstrate that the proposed method can successfully identify vortex rotation axis lines without any user-specified threshold, so that the proposed method is very straightforward, robust and efficient.展开更多
Our goal was to establish two new predictive models of prostate cancer to determine whether to require a prostate biopsy when the prostate-specific antigen level is in the diagnostic gray zone.A retrospective analysis...Our goal was to establish two new predictive models of prostate cancer to determine whether to require a prostate biopsy when the prostate-specific antigen level is in the diagnostic gray zone.A retrospective analysis of 197 patients undergoing prostate biopsy with prostate-specific antigens between 4 and 10 ng ml^?1 was conducted.Of these,47 patients were confirmed to have cancer,while the remaining 150 patients were diagnosed with benign prostate disease after examining biopsy pathology.Two multivariate logistic regression models were established including age,prostate volumes,free/total prostate-specific antigen ratio,and prostate-specific antigen density using SPSS 19.0 to obtain the predicted probability and Logit P,and then,two receiver operating characteristic(ROC)curves were drawn to obtain the best cutoff value for prostate biopsy:one for the group of all the prostate cancers and one for the group of clinically significant prostate cancers.The best cutoff value for prostate biopsy was 0.25 from the multivariate logistic regression ROC curve model of all the prostate cancers,which gave a sensitivity of 75.4%and a specificity of 75.8%.The best cutoff value for prostate biopsy was 0.20 from the multivariate logistic regression model of clinically significant prostate cancers,which gave a sensitivity of 76.7%and a specificity of 80.1%.We identified the best cutoff values for prostate biopsy(0.25 for all prostate cancers and 0.20 for clinically significant prostate cancers)to determine whether to require prostate biopsy when the PSA level is in the diagnostic gray zone.展开更多
基金supported by the Natural Science Basic Research Program of Shaanxi(Program No.2022JQ-593)。
文摘In order to improve the performance of UAV's autonomous maneuvering decision-making,this paper proposes a decision-making method based on situational continuity.The algorithm in this paper designs a situation evaluation function with strong guidance,then trains the Long Short-Term Memory(LSTM)under the framework of Deep Q Network(DQN)for air combat maneuvering decision-making.Considering the continuity between adjacent situations,the method takes multiple consecutive situations as one input of the neural network.To reflect the difference between adjacent situations,the method takes the difference of situation evaluation value as the reward of reinforcement learning.In different scenarios,the algorithm proposed in this paper is compared with the algorithm based on the Fully Neural Network(FNN)and the algorithm based on statistical principles respectively.The results show that,compared with the FNN algorithm,the algorithm proposed in this paper is more accurate and forwardlooking.Compared with the algorithm based on the statistical principles,the decision-making of the algorithm proposed in this paper is more efficient and its real-time performance is better.
文摘BACKGROUND Myopia,as one of the common ocular diseases,often occurs in adolescence.In addition to the harm from itself,it may also lead to serious complications.Thus,prevention and control of myopia are attracting more and more attention.Previous research revealed that single-focal glasses and orthokeratology lenses(OK lenses)played an important part in slowing down myopia and preventing high myopia.AIM To compare the clinical effects of OK lenses and frame glasses against the increase of diopter in adolescent myopia and further explore the mechanism of the OK lens.METHODS Changes in diopter and axial length were collected among 70 adolescent myopia patients(124 eyes)wearing OK lenses for 1 year(group A)and 59 adolescent myopia patients(113 eyes)wearing frame glasses(group B).Refractive states of their retina were inspected through multispectral refraction topography.The obtained hyperopic defocus was analyzed for the mechanism of OK lenses on slowing down the increase of myopic diopter by delaying the increase of ocular axis length and reducing the near hyperopia defocus.RESULTS Teenagers in groups A and B were divided into low myopia(0 D--3.00 D)and moderate myopia(-3.25 D--6.00 D),without statistical differences among gender and age.After 1-year treatment,the increase of diopter and axis length and changes of retinal hyperopic defocus amount of group A were significantly less than those of group B.According to the multiple linear analysis,the retinal defocus in the upper,lower,nasal,and temporal directions had almost the same effect on the total defocus.The amount of peripheral retinal defocus(15°-53°)in group A was significantly lower than that in group B.CONCLUSION Multispectral refraction topography is progressive and instructive in clinical prevention and control of myopia.
基金supported by the National Natural Science Foundation of China (Grant No. 91530325).
文摘Six core issues for vortex definition and identification concern with (1) the absolute strength,(2) the relative strength,(3) the rotational axis,(4) the vortex core center,(5) the vortex core size, and (6) the vortex boundary (Liu C. 2019). However, most of the currently popular vortex identification methods, including the Q criterion, the criterion and the Acj criterion etc., are Eulerian local region-type vortex identification criteria and can only approximately identify the vortex boundary by somewhat arbitrary threshold. On the other hand, the existing Eulerian local line-type methods, which seek to extract line-type features such as vortex core line, are not entirely satisfactory since most of these methods are based on vorticity or pressure minimum that will fail in many cases. The key issue is the lack of a reasonable mathematical definition for vortex core center. To address this issue, a Liutex (previously named Rortex) based definition of vortex core center is proposed in this paper. The vortex core center, also called vortex rotation axis line here, is defined as a line where the Liutex magnitude gradient vector is aligned with the Liutex vector, which mathematically implies that the cross product of the Liutex magnitude gradient vector and the Liutex vector on the line is equal to zero. Based on this definition, a novel three-step method for extracting vortex rotation axis lines is presented. Two test cases, namely the Burgers vortex and hairpin vortices, are examined to justify the proposed method. The results demonstrate that the proposed method can successfully identify vortex rotation axis lines without any user-specified threshold, so that the proposed method is very straightforward, robust and efficient.
文摘Our goal was to establish two new predictive models of prostate cancer to determine whether to require a prostate biopsy when the prostate-specific antigen level is in the diagnostic gray zone.A retrospective analysis of 197 patients undergoing prostate biopsy with prostate-specific antigens between 4 and 10 ng ml^?1 was conducted.Of these,47 patients were confirmed to have cancer,while the remaining 150 patients were diagnosed with benign prostate disease after examining biopsy pathology.Two multivariate logistic regression models were established including age,prostate volumes,free/total prostate-specific antigen ratio,and prostate-specific antigen density using SPSS 19.0 to obtain the predicted probability and Logit P,and then,two receiver operating characteristic(ROC)curves were drawn to obtain the best cutoff value for prostate biopsy:one for the group of all the prostate cancers and one for the group of clinically significant prostate cancers.The best cutoff value for prostate biopsy was 0.25 from the multivariate logistic regression ROC curve model of all the prostate cancers,which gave a sensitivity of 75.4%and a specificity of 75.8%.The best cutoff value for prostate biopsy was 0.20 from the multivariate logistic regression model of clinically significant prostate cancers,which gave a sensitivity of 76.7%and a specificity of 80.1%.We identified the best cutoff values for prostate biopsy(0.25 for all prostate cancers and 0.20 for clinically significant prostate cancers)to determine whether to require prostate biopsy when the PSA level is in the diagnostic gray zone.