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Diffusion tensor imaging of spinal microstructure in healthy adults: improved resolution with the readout segmentation of long variable echo-trains
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作者 Bu-tian Zhang Meng Li +3 位作者 Li-li Yu yi-meng dai Shao-nan Yu Jin-lan Jiang 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第12期2067-2070,共4页
Diffusion tensor imaging plays an important role in the accurate diagnosis and prognosis of spinal cord diseases. However, because of technical limitations, the imaging sequences used in this technique cannot reveal t... Diffusion tensor imaging plays an important role in the accurate diagnosis and prognosis of spinal cord diseases. However, because of technical limitations, the imaging sequences used in this technique cannot reveal the fine structure of the spinal cord with precision. We used the readout segmentation of long variable echo-trains(RESOLVE) sequence in this cross-sectional study of 45 healthy volunteers aged 20 to 63 years. We found that the RESOLVE sequence significantly increased the resolution of the diffusion images and improved the median signal-to-noise ratio of the middle(C4–6) and lower(C7–T1) cervical segments to the level of the upper cervical segment. In addition, the values of fractional anisotropy and radial diffusivity were significantly higher in white matter than in gray matter. Our study verified that the RESOLVE sequence could improve resolution of diffusion tensor imaging in clinical applications and provide accurate baseline data for the diagnosis and treatment of cervical spinal cord diseases. 展开更多
关键词 nerve regeneration diffusion tensor imaging cervical spinal cord MICROSTRUCTURE gray matter white matter readout segmentationof long variable echo-train sequence signal-to-noise ratio fractional anisotropy neural regeneration
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