Bipolar disorder(BD)is a debilitating psychiatric mood dis-order affecting approximately 1%-3%of the population worldwide(Merikangas,2007).Bipolar disorder is characterized by recurrent episodes of depression,hypomani...Bipolar disorder(BD)is a debilitating psychiatric mood dis-order affecting approximately 1%-3%of the population worldwide(Merikangas,2007).Bipolar disorder is characterized by recurrent episodes of depression,hypomania,mania,or mixed states,and it has a poor outcome,with high rates of relapse,lingering residual symptoms,cognitive impairment,and functional impairment(Moreno et al.,2007)Although various etiopathological hypotheses concerning the disease have been reported,the pathophysiology underlying BD remains poody understood(Gawryluk and Young,2011).展开更多
文摘Bipolar disorder(BD)is a debilitating psychiatric mood dis-order affecting approximately 1%-3%of the population worldwide(Merikangas,2007).Bipolar disorder is characterized by recurrent episodes of depression,hypomania,mania,or mixed states,and it has a poor outcome,with high rates of relapse,lingering residual symptoms,cognitive impairment,and functional impairment(Moreno et al.,2007)Although various etiopathological hypotheses concerning the disease have been reported,the pathophysiology underlying BD remains poody understood(Gawryluk and Young,2011).