CAV driving safety monitoring and warning via V2X-based edge computing system

Driving safety and accident prevention are attracting increasing global interest.Current safety monitoring systems often face challenges such as limited spatiotemporal coverage and accuracy,leading to delays in alerting drivers about potential hazards.This study explores the use of edge computing for monitoring vehicle motion and issuing accident warnings,such as lane departures and vehicle collisions.Unlike traditional systems that depend on data from single vehicles,the cooperative vehicle-infrastructure system collects data directly from connected and automated vehicles(CAVs)via vehicle-to-everything communication.This approach facilitates a comprehensive assessment of each vehicle’s risk.We propose algorithms and specific data structures for evaluating accident risks associated with different CAVs.Furthermore,we examine the prerequisites for data accuracy and transmission delay to enhance the safety of CAV driving.The efficacy of this framework is validated through both simulated and real-world road tests,proving its utility in diverse driving conditions.

The crosstalk between ferroptosis and anti-tumor immunity in the tumor microenvironment:molecular mechanisms and therapeutic controversy

The advent of immunotherapy has significantly reshaped the landscape of cancer treatment,greatly enhancing therapeutic outcomes for multiple types of cancer.However,only a small subset of individuals respond to it,underscoring the urgent need for new methods to improve its response rate.Ferroptosis,a recently discovered form of programmed cell death,has emerged as a promising approach for anti-tumor therapy,with targeting ferroptosis to kill tumors seen as a potentially effective strategy.Numerous studies suggest that inducing ferroptosis can synergistically enhance the effects of immunotherapy,paving the way for a promising combined treatment method in the future.Nevertheless,recent research has raised concerns about the potential negative impacts on anti-tumor immunity as a consequence of inducing ferroptosis,leading to conflicting views within the scientific community about the interplay between ferroptosis and anti-tumor immunity,thereby underscoring the necessity of a comprehensive review of the existing literature on this relationship.Previous reviews on ferroptosis have touched on related content,many focusing primarily on the promoting role of ferroptosis on anti-tumor immunity while overlooking recent evidence on the inhibitory effects of ferroptosis on immunity.Others have concentrated solely on discussing related content either from the perspective of cancer cells and ferroptosis or from immune cells and ferroptosis.Given that both cancer cells and immune cells exist in the tumor microenvironment,a one-sided discussion cannot comprehensively summarize this topic.Therefore,from the perspectives of both tumor cells and tumor-infiltrating immune cells,we systematically summarize the current conflicting views on the interplay between ferroptosis and anti-tumor immunity,intending to provide potential explanations and identify the work needed to establish a translational basis for combined ferroptosis-targeted therapy and immunotherapy in treating tumors.

2018年中国基本城市土地利用类型制图(EULUC-China)

土地利用是人类活动在土地空间的重要表现形式.由于数据和资金支持的限制,全国尺度城市土地利用的遥感制图研究仍相对缺乏.针对这一难题,本文提出了涵盖居住-休闲-交通-工业-办公五大类用地的"基本城市土地利用类型(EULUC)"的概念,并综合利用2018年的10米分辨率哨兵卫星数据,OpenStreetMap,珞珈一号夜间灯光数据,以及腾讯移动定位和高德兴趣点(POI)等社会大数据,实现了全国范围内城市土地利用制图.第一版中国基本城市土地利用制图结果共包括440798个地块(除道路用地),5大一级类和12个二级类总体分类精度分别为61.2%和57.5%.这是中国首套结合遥感和众源大数据,以地块尺度生产的面向对象的高分辨率城市土地利用图.

Dynamic Parameters Cellular Automaton Model for Passengers in Subway

To simulate the passenger behavior in subway system, a Dynamic Parameters Cellular Automaton(DPCA) model is put forward in this paper. Pedestrian traffic flows during waiting, getting on or off, and traveling can be simulated. The typical scenario in Beijing Subway Line 13 is modeled to analyze the passenger behavior in subway system. By comparing simulation results with statistical ones, the correctness and practicality of the DPCA model are verified. At last, the additional results made by DPCA model can make contribution to passenger comfort analysis and pedestrian facility planning and guidance.

A Generalized Comfort Function of Subway Systems Based on a Nested Logit Model

With rapid urbanization,subway systems are widely acknowledged as one of the best solutions to urban transportation problems.The operators or managers of subway systems should pay more attention to passenger＇s perceptions of service quality to maintain its competitive position.Taking the traffic state,efficiency,and environmental impact into consideration,the concept of generalized comfort is proposed in this paper.Based on a nested logit model,the selection probability for each factor in a generalized comfort function can be estimated using a nested structure.A certain factor is considered to be more significant in a generalized comfort function than others,when the corresponding probability of this factor is higher in value.Using stated preference and revealed preference data about passenger travel behavior obtained from the Beijing subway,the parameters of generalized comfort function are estimated by maximum likelihood techniques.