Natural disaster or large-scale unexpected events easily make the terrestrial network overloaded,paralyzed, or totally destroyed. It is highly demanded to build an emergency network which can be deployed rapidly, offe...Natural disaster or large-scale unexpected events easily make the terrestrial network overloaded,paralyzed, or totally destroyed. It is highly demanded to build an emergency network which can be deployed rapidly, offer high data rate and wide coverage. The emergence of aerial platforms especially the low altitude platforms(LAPs) indicates a stable and reliable direction for the development of emergency network. Hybrid satellite-aerial-terrestrial(HSAT) networks have the ability to provide effective services rather than traditional infrastructures during the emergency situation. In this paper, the aerial platforms and the HSAT networks are surveyed and the key technologies are discussed from several aspects. The challenges of the HSAT networks are also outlined finally.展开更多
Oxidation corrosion of steels usually occurs in contact with the oxygen-contained environment, which is accelerated by high oxygen concentration and irradiation. The oxidation mechanism of steels is investigated by th...Oxidation corrosion of steels usually occurs in contact with the oxygen-contained environment, which is accelerated by high oxygen concentration and irradiation. The oxidation mechanism of steels is investigated by the adsorption/solution of oxygen atoms on/under body-centered-cubic(bcc) iron surfaces, and diffusion of oxygen atoms on the surface and in the near-surface region. Energetic results indicate that oxygen atoms prefer to adsorb at hollow and long-bridge positions on the Fe(100) and(110) surfaces, respectively. As the coverage of oxygen atoms increases, oxygen atoms would repel each other and gradually dissolve in the near-surface and bulk region. As vacancies exist, oxygen atoms are attracted by vacancies, especially in the near-surface and bulk region. Dynamic results indicate that the diffusion of O atoms on surfaces is easier than that into near-surface, which is affected by oxygen coverage and vacancies. Moreover, the effects of oxygen concentration and irradiation on oxygen density in the near-surface and bulk region are estimated by the Mc Lean’s model with a simple hypothesis.展开更多
Herein we develop a unique differentiated-uptake strategy capable of efficient and high-purity isolation of genuine drug-resistant(DR)cells from three types of drug-surviving cancer cells,which include paclitaxel-surv...Herein we develop a unique differentiated-uptake strategy capable of efficient and high-purity isolation of genuine drug-resistant(DR)cells from three types of drug-surviving cancer cells,which include paclitaxel-surviving human ovarian OVCAR-3 cancer cells and human lung carcinoma A549/Taxol cells,and doxorubicin-surviving human immortalized myelogenous leukemia K562/ADR cells.By using this strategy which relies on fluorescent glycan nanoparticle(FGNP)-based fluorescence-activated cell sorting(FACS)assays,two subpopulations with distinct fluorescences existing in drug-surviving OVCAR-3 cells were separated,and we found that the lower fluorescence(LF)subpopulation consisted of DR cells,while the higher fluorescence(HF)subpopulation was comprised of non-DR cells.Besides,the DR cells and their progenies were found distinct in their increased expression of drug-resistant genes.More intriguingly,by using the FGNP-based FACS assay to detect DR/non-DR phenotypes,we found that the DR phenotype had a potential to differentiate into the non-DR progeny,which demonstrates the differentiation feature of stem-like cancer cells.Further research disclosed that the assay can quantitatively detect the degree of drug resistance in DR cells,as well as the reversal of drug resistance that are tackled by various therapeutic methods.The strategy thus paves the way to develop theranostic approaches associated with chemotherapy-resistance and cancer stemness.展开更多
Erratum to Nano Research 2020,13(11):3110-3122 https://d0i.0rg/l 0.1007/s 12274-020-2981-8 The article Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells wi...Erratum to Nano Research 2020,13(11):3110-3122 https://d0i.0rg/l 0.1007/s 12274-020-2981-8 The article Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells with differentiation potential,written by Chenglong Wang et al.,was erroneously originally published electronically on the publishers internet portal(currently SpringerLink)on 10 August 2020 with the Acknowledgements.展开更多
基金supported by the National 863 Project under Grant No.2015AA015701National Nature Science Foundation of China under Grant No. 61421061
文摘Natural disaster or large-scale unexpected events easily make the terrestrial network overloaded,paralyzed, or totally destroyed. It is highly demanded to build an emergency network which can be deployed rapidly, offer high data rate and wide coverage. The emergence of aerial platforms especially the low altitude platforms(LAPs) indicates a stable and reliable direction for the development of emergency network. Hybrid satellite-aerial-terrestrial(HSAT) networks have the ability to provide effective services rather than traditional infrastructures during the emergency situation. In this paper, the aerial platforms and the HSAT networks are surveyed and the key technologies are discussed from several aspects. The challenges of the HSAT networks are also outlined finally.
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2017YFE0302400 and 2017YFA0402803)the National Nature Science Foundation of China(Grant Nos.11735015,52071314,51871207,U1832206,12075274,U1967211,52171084)Hefei Advanced Computing Center。
文摘Oxidation corrosion of steels usually occurs in contact with the oxygen-contained environment, which is accelerated by high oxygen concentration and irradiation. The oxidation mechanism of steels is investigated by the adsorption/solution of oxygen atoms on/under body-centered-cubic(bcc) iron surfaces, and diffusion of oxygen atoms on the surface and in the near-surface region. Energetic results indicate that oxygen atoms prefer to adsorb at hollow and long-bridge positions on the Fe(100) and(110) surfaces, respectively. As the coverage of oxygen atoms increases, oxygen atoms would repel each other and gradually dissolve in the near-surface and bulk region. As vacancies exist, oxygen atoms are attracted by vacancies, especially in the near-surface and bulk region. Dynamic results indicate that the diffusion of O atoms on surfaces is easier than that into near-surface, which is affected by oxygen coverage and vacancies. Moreover, the effects of oxygen concentration and irradiation on oxygen density in the near-surface and bulk region are estimated by the Mc Lean’s model with a simple hypothesis.
基金supported by the National Natural Science Foundation of China(Nos.21871180 and 81872121)the“Shuguang Program”supported by the Shanghai Education Development Foundation and the Shanghai Municipal Education Commission(No.17SG12)+2 种基金the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning(No.SHDP201802)the Science and Technology Commission of Shanghai Municipality(No.18520710300 and 17ZR1404100)the Biomedical Interdisciplinary Research Foundation of SJTU(No.YG2019QNB34).
文摘Herein we develop a unique differentiated-uptake strategy capable of efficient and high-purity isolation of genuine drug-resistant(DR)cells from three types of drug-surviving cancer cells,which include paclitaxel-surviving human ovarian OVCAR-3 cancer cells and human lung carcinoma A549/Taxol cells,and doxorubicin-surviving human immortalized myelogenous leukemia K562/ADR cells.By using this strategy which relies on fluorescent glycan nanoparticle(FGNP)-based fluorescence-activated cell sorting(FACS)assays,two subpopulations with distinct fluorescences existing in drug-surviving OVCAR-3 cells were separated,and we found that the lower fluorescence(LF)subpopulation consisted of DR cells,while the higher fluorescence(HF)subpopulation was comprised of non-DR cells.Besides,the DR cells and their progenies were found distinct in their increased expression of drug-resistant genes.More intriguingly,by using the FGNP-based FACS assay to detect DR/non-DR phenotypes,we found that the DR phenotype had a potential to differentiate into the non-DR progeny,which demonstrates the differentiation feature of stem-like cancer cells.Further research disclosed that the assay can quantitatively detect the degree of drug resistance in DR cells,as well as the reversal of drug resistance that are tackled by various therapeutic methods.The strategy thus paves the way to develop theranostic approaches associated with chemotherapy-resistance and cancer stemness.
基金This work was financially supported by the National Natural Science Foundation of China(Nos.21871180 and 81872121)the“Shuguang Program”supported by the Shanghai Education Development Foundation and the Shanghai Municipal Education Commission(No.17SG12)+2 种基金the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning(No.SHDP201802)the Science and Technology Commission of Shanghai Municipality(No.18520710300 and 18JC1413500)the Biomedical Interdisciplinary Research Foundation of SJTU(No.YG2019QNB34).
文摘Erratum to Nano Research 2020,13(11):3110-3122 https://d0i.0rg/l 0.1007/s 12274-020-2981-8 The article Fluorescent glycan nanoparticle-based FACS assays for the identification of genuine drug-resistant cancer cells with differentiation potential,written by Chenglong Wang et al.,was erroneously originally published electronically on the publishers internet portal(currently SpringerLink)on 10 August 2020 with the Acknowledgements.
