Detecting short-term gravitational waves from post-merger hyper-massive neutron stars with a kilohertz detector

Gravitational waves emanating from binary neutron star inspirals,alongside electromagnetic transients resulting from the aftermath of the GW170817 merger,have been successfully detected.However,the intricate post-merger dynamics that bridge these two sets of observables remain enigmatic.This includes if,and when,the post-merger remnant star collapses to a black hole,and what are the necessary conditions to power a short gamma-ray burst,and other observed electromagnetic counterparts.Our focus is on the detection of gravitational wave(GW)emissions from hyper-massive neutron stars(NSs)formed through binary neutron star(BNS)mergers.Utilizing several kilohertz GW detectors,we simulate BNS mergers within the detection limits of LIGO-Virgo-KARGA O4.Our objective is to ascertain the fraction of simulated sources that may emit detectable post-merger GW signals.For kilohertz detectors equipped with a new cavity design,we estimate that approximately 1.1%-32%of sources would emit a detectable post-merger GW signal.This fraction is contingent on the mass converted into gravitational wave energy,ranging from 0.01M_(sun)to 0.1M_(sun).Furthermore,by evaluating other well-regarded proposed kilohertz GW detectors,we anticipate that the fraction can increase to as much as 2.1%-61%under optimal performance conditions.

Biosynthesis of fungus-based oral selenium microcarriers for radioprotection and immuno-homeostasis shaping against radiation-induced heart disease

Radiation-induced heart disease(RIHD),characterized by severe oxidative stress and immune dysregulation,is a serious condition affecting cancer patients undergoing thoracic radiation.Unfortunately,clinical interventions for RIHD are lacking.Selenium(Se)is a trace element with excellent antioxidant and immune-modulatory properties.However,its application in heart radioprotection remains challenging.Herein,we developed a novel bioactive Cordyceps militaris-based Se oral delivery system(Se@CM),which demonstrated superior radioprotection effects in vitro against X-ray-induced damage in H9C2 cells through suppressing excessive ROS generation,compared to the radioprotectant Amifostine.Moreover,Se@CM exhibited exceptional cardioprotective effects in vivo against X-ray irradiation,reducing cardiac dysfunction and myocardial fibrosis by balancing the redox equilibrium and modulating the expression of Mn-SOD and MDA.Additionally,Se@CM maintained immuno-homeostasis,as evidenced by the upregulated population of T cells and M2 macrophages through modulation of selenoprotein expression after irradiation.Together,these results highlight the remarkable antioxidant and immunity modulation properties of Se@CM and shed light on its promising application for cardiac protection against IR-induced disease.This research provides valuable insights into developing effective strategies for preventing and managing RIHD.