Objective:To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis.Methods:Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study...Objective:To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis.Methods:Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study.Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically.Results:Serum raalondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls(P<0.00l). Conclusions:These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients.Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.展开更多
基金Supported by Scientific Research Projects Governing Unit ofGaziantep University(No.TF:00 04)
文摘Objective:To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis.Methods:Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study.Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically.Results:Serum raalondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls(P<0.00l). Conclusions:These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients.Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.
