Syphilis is a sexually transmitted disease(STD)caused by the spirochete bacterium Treponema pallidum subspecies pallidum.Historically,syphilis was called as the“great pox”in order to distinguish it from smallpox and...Syphilis is a sexually transmitted disease(STD)caused by the spirochete bacterium Treponema pallidum subspecies pallidum.Historically,syphilis was called as the“great pox”in order to distinguish it from smallpox and given many national attributions,such as the French pox,the English pox,and the Italian pox,due to that the disease was often believed to be spread by sailors and soldiers in the country during their unprotected sexual contact with local prostitutes.1 The French pox was widely used before it was named syphilis by the Italian physician and poet Girolamo Fracastoro in 1530.2 Syphilis first reached Canton(Guangzhou)of China through the sea in 1505 and was called“Canton sores”or“Canton rash”(kuang chuang).However,“plum-blossom sores”(yangmei chuang)was more widely used in medical records in China because they had a shape resembling plum-blossoms.Syphilis is transmitted through unprotected sexual contact with an infected person.It can also be passed from an infected mother to her unborn child.If left untreated,syphilis often progresses to later stages and can cause heart problems,psychological disorders,blindness,and death.In era of human immunodeficiency virus(HIV)epidemic,syphilis infection has become a facilitating factor to increase the risk of contracting HIV by up to four-fold and transmitting HIV by up to nine-fold.3 China has a long history of syphilis epidemic but the great successes in control of the disease have been made during the past 70 years in China.展开更多
Lymphogranuloma venereum （LGV） is a systemic sexually transmitted disease caused by Chlamydia trachomatis （C. trachomatis） L1, L2 and L3, the organism gains entrance through skin breaks and abrasions and travels v...Lymphogranuloma venereum （LGV） is a systemic sexually transmitted disease caused by Chlamydia trachomatis （C. trachomatis） L1, L2 and L3, the organism gains entrance through skin breaks and abrasions and travels via the lymphatics to multiply within mononuclear phagocytes in regional lymph nodes, The clinical presentation of LGV depends on the sex of the patient, mode of sexual contact （e.g. vaginal or anal sex） and the stage of the disease. LGV is diagnosed in men up to 6 times more frequently than in women, but the infected women are more likely developed to late stage. LGV is rare in China, however the incidence was increasing in recent years. In this paper we diagnosed a case of LGV, and confirmed this case was caused by L3 serovar of C. trachomatis by using genotype test.展开更多
Introduction Chlamydia trachomatis(CT)and Neisseria gonorrhoeae(NG)infections are the most prevalent sexually transmitted infections among adults globally,1 and most commonly cause urogenital infections but also ocula...Introduction Chlamydia trachomatis(CT)and Neisseria gonorrhoeae(NG)infections are the most prevalent sexually transmitted infections among adults globally,1 and most commonly cause urogenital infections but also ocular infections,which often occur in newborns but rarely in adults.We herein report such a case of adult conjunctivitis caused by CT and NG coinfection.展开更多
文摘Syphilis is a sexually transmitted disease(STD)caused by the spirochete bacterium Treponema pallidum subspecies pallidum.Historically,syphilis was called as the“great pox”in order to distinguish it from smallpox and given many national attributions,such as the French pox,the English pox,and the Italian pox,due to that the disease was often believed to be spread by sailors and soldiers in the country during their unprotected sexual contact with local prostitutes.1 The French pox was widely used before it was named syphilis by the Italian physician and poet Girolamo Fracastoro in 1530.2 Syphilis first reached Canton(Guangzhou)of China through the sea in 1505 and was called“Canton sores”or“Canton rash”(kuang chuang).However,“plum-blossom sores”(yangmei chuang)was more widely used in medical records in China because they had a shape resembling plum-blossoms.Syphilis is transmitted through unprotected sexual contact with an infected person.It can also be passed from an infected mother to her unborn child.If left untreated,syphilis often progresses to later stages and can cause heart problems,psychological disorders,blindness,and death.In era of human immunodeficiency virus(HIV)epidemic,syphilis infection has become a facilitating factor to increase the risk of contracting HIV by up to four-fold and transmitting HIV by up to nine-fold.3 China has a long history of syphilis epidemic but the great successes in control of the disease have been made during the past 70 years in China.
文摘Lymphogranuloma venereum （LGV） is a systemic sexually transmitted disease caused by Chlamydia trachomatis （C. trachomatis） L1, L2 and L3, the organism gains entrance through skin breaks and abrasions and travels via the lymphatics to multiply within mononuclear phagocytes in regional lymph nodes, The clinical presentation of LGV depends on the sex of the patient, mode of sexual contact （e.g. vaginal or anal sex） and the stage of the disease. LGV is diagnosed in men up to 6 times more frequently than in women, but the infected women are more likely developed to late stage. LGV is rare in China, however the incidence was increasing in recent years. In this paper we diagnosed a case of LGV, and confirmed this case was caused by L3 serovar of C. trachomatis by using genotype test.
基金We thank William Shafer for his valuable comments.This study was supported by grants from the Key Technology Program of Zhongshan(No.2017B1064)the Chinese Academy of Medical Sciences Initiative for Innovative Medicine(No.2016-I2M-3-021)the Jiangsu Natural Science Foundation(No.BK20171133).
文摘Introduction Chlamydia trachomatis(CT)and Neisseria gonorrhoeae(NG)infections are the most prevalent sexually transmitted infections among adults globally,1 and most commonly cause urogenital infections but also ocular infections,which often occur in newborns but rarely in adults.We herein report such a case of adult conjunctivitis caused by CT and NG coinfection.
