The emerging photovoltaic(PV)technologies,such as organic and perovskite PVs,have the characteristics of complex compositions and processing,resulting in a large multidimensional parameter space for the development an...The emerging photovoltaic(PV)technologies,such as organic and perovskite PVs,have the characteristics of complex compositions and processing,resulting in a large multidimensional parameter space for the development and optimization of the technologies.Traditional manual methods are time-consuming and laborintensive in screening and optimizing material properties.Materials genome engineering(MGE)advances an innovative approach that combines efficient experimentation,big database and artificial intelligence(AI)algorithms to accelerate materials research and development.High-throughput(HT)research platforms perform multidimensional experimental tasks rapidly,providing a large amount of reliable and consistent data for the creation of materials databases.Therefore,the development of novel experimental methods combining HT and AI can accelerate materials design and application,which is beneficial for establishing material-processing-property relationships and overcoming bottlenecks in the development of emerging PV technologies.This review introduces the key technologies involved in MGE and overviews the accelerating role of MGE in the field of organic and perovskite PVs.展开更多
Background： It is important to achieve the definitive pathogen identification in hospital-acquired pneumonia （HAP）, but the traditional culture results always delay the target antibiotic therapy. We assessed the me...Background： It is important to achieve the definitive pathogen identification in hospital-acquired pneumonia （HAP）, but the traditional culture results always delay the target antibiotic therapy. We assessed the method called quantitative loop-mediated isothermal amplification （qLAMP） as a new implement for steering of the antibiotic decision-making in HAP. Methods： Totally, 76 respiratory tract aspiration samples were prospectively collected from 60 HAP patients. DNA was isolated from these samples. Specific DNA fragments for identifying 11 pneumonia-related bacteria were amplified by qLAMP assay. Culture results of these patients were compared with the qLAMP results. Clinical data and treatment strategies were analyzed to evaluate the effects of qLAMP results on clinical data. McNemar test and Fisher＇s exact test were used for statistical analysis. Results： The detection of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Stenotrophomonas maltophilia, Streptococcus pneumonia, and Acinetobacter baumannii by qLAMP was consistent with sputum culture （P 〉 0.05）. The qLAMP results of 4 samples for Haemophilus influenzae, Legionella pneumophila, or Mvcoplasma pneumonia （MP） were inconsistent with culture results; however, clinical data revealed that the qLAMP results were all reliable except 1 MP positive sample due to the lack of specific species identified in the final diagnosis. The improvement of clinical condition was more significant （P 〈 0.001） in patients with pathogen target-driven therapy based on qLAMP results than those with empirical therapy. Conclusion： qLAMP is a more promising method for detection of pathogens in an early, rapid, sensitive, and specific manner than culture.展开更多
The distributed acoustic sensing （DAS） has been extensively studied and widely used. A distributed acoustic sensing system based on the unbalanced Michelson interferometer with phase generated carrier （PGC） demodu...The distributed acoustic sensing （DAS） has been extensively studied and widely used. A distributed acoustic sensing system based on the unbalanced Michelson interferometer with phase generated carrier （PGC） demodulation was designed and tested. The system could directly obtain the phase, amplitude, frequency response, and location information of sound wave at the same time and measurement at all points along the sensing fiber simultaneously. Experiments showed that the system successfully measured the acoustic signals with a phase-pressure sensitivity about -148dB （re rad/μPa） and frequency response ripple less than 1.5 dB. The further field experiment showed that the system could measure signals at all points along the sensing fiber simultaneously.展开更多
We demonstrate a distributed optical fiber sensing system based on the Michelson interferometer of the phase sensitive optical time domain reflectometer （q0-OTDR） for acoustic measurement. Phase, amplitude, frequenc...We demonstrate a distributed optical fiber sensing system based on the Michelson interferometer of the phase sensitive optical time domain reflectometer （q0-OTDR） for acoustic measurement. Phase, amplitude, frequency response, and location information can be directly obtained at the same time by using the passive 3 ×3 coupler demodulation. We also set an experiment and successfully restore the acoustic information. Meanwhile, our system has preliminary realized acoustic-phase sensitivity around -150 dB （re rad/μPa） in the experiment.展开更多
To the Editor:Community-acquired pneumonia(CAP)is one of the most common infectious diseases,causing high morbidity and mortality.High altitudes are characterized by a hypoxic environment with low barometric pressure,...To the Editor:Community-acquired pneumonia(CAP)is one of the most common infectious diseases,causing high morbidity and mortality.High altitudes are characterized by a hypoxic environment with low barometric pressure,increased ultraviolet radiation,and low humidity.Hypoxia can disturb normal homeostasis of the immune system,especially impairing the function of the T lymphocytes,leading to an increased susceptibility to bacterial infection.The respiratory symptoms of CAP at high altitudes are similar to that of high-altitude pulmonary edema.展开更多
We propose a new non-intrusive flow measurement method using the distributed feedback fiber laser(DFB-FL)as a sensor to monitor flow in the pipe.The relationship between the wavelength of the DFB-FL and the liquid flo...We propose a new non-intrusive flow measurement method using the distributed feedback fiber laser(DFB-FL)as a sensor to monitor flow in the pipe.The relationship between the wavelength of the DFB-FL and the liquid flow rate in the pipeline is derived.Under the guidance of this theory,the design and test of the flow sensor is completed.The response curve is relatively flat in the frequency range of 10 Hz to 500 Hz,and the response of the flow sensor has high linearity.The flow from 0.6 m^3/h to 25.5 m^3/h is accurately measured under the energy analysis method in different frequency intervals.A minimum flow rate of 0.046 m/s is achieved.The experimental results demonstrate the feasibility of the new non-intrusive flow measurement method based on the DFB-FL and accurate measurement of small flow rates.展开更多
基金the financial support from the National Natural Science Foundation of China(52394273 and 52373179).
文摘The emerging photovoltaic(PV)technologies,such as organic and perovskite PVs,have the characteristics of complex compositions and processing,resulting in a large multidimensional parameter space for the development and optimization of the technologies.Traditional manual methods are time-consuming and laborintensive in screening and optimizing material properties.Materials genome engineering(MGE)advances an innovative approach that combines efficient experimentation,big database and artificial intelligence(AI)algorithms to accelerate materials research and development.High-throughput(HT)research platforms perform multidimensional experimental tasks rapidly,providing a large amount of reliable and consistent data for the creation of materials databases.Therefore,the development of novel experimental methods combining HT and AI can accelerate materials design and application,which is beneficial for establishing material-processing-property relationships and overcoming bottlenecks in the development of emerging PV technologies.This review introduces the key technologies involved in MGE and overviews the accelerating role of MGE in the field of organic and perovskite PVs.
文摘Background： It is important to achieve the definitive pathogen identification in hospital-acquired pneumonia （HAP）, but the traditional culture results always delay the target antibiotic therapy. We assessed the method called quantitative loop-mediated isothermal amplification （qLAMP） as a new implement for steering of the antibiotic decision-making in HAP. Methods： Totally, 76 respiratory tract aspiration samples were prospectively collected from 60 HAP patients. DNA was isolated from these samples. Specific DNA fragments for identifying 11 pneumonia-related bacteria were amplified by qLAMP assay. Culture results of these patients were compared with the qLAMP results. Clinical data and treatment strategies were analyzed to evaluate the effects of qLAMP results on clinical data. McNemar test and Fisher＇s exact test were used for statistical analysis. Results： The detection of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Stenotrophomonas maltophilia, Streptococcus pneumonia, and Acinetobacter baumannii by qLAMP was consistent with sputum culture （P 〉 0.05）. The qLAMP results of 4 samples for Haemophilus influenzae, Legionella pneumophila, or Mvcoplasma pneumonia （MP） were inconsistent with culture results; however, clinical data revealed that the qLAMP results were all reliable except 1 MP positive sample due to the lack of specific species identified in the final diagnosis. The improvement of clinical condition was more significant （P 〈 0.001） in patients with pathogen target-driven therapy based on qLAMP results than those with empirical therapy. Conclusion： qLAMP is a more promising method for detection of pathogens in an early, rapid, sensitive, and specific manner than culture.
文摘The distributed acoustic sensing （DAS） has been extensively studied and widely used. A distributed acoustic sensing system based on the unbalanced Michelson interferometer with phase generated carrier （PGC） demodulation was designed and tested. The system could directly obtain the phase, amplitude, frequency response, and location information of sound wave at the same time and measurement at all points along the sensing fiber simultaneously. Experiments showed that the system successfully measured the acoustic signals with a phase-pressure sensitivity about -148dB （re rad/μPa） and frequency response ripple less than 1.5 dB. The further field experiment showed that the system could measure signals at all points along the sensing fiber simultaneously.
基金This work was supported by the Shandong Natural Science Foundation （No. ZR2013FL028）, Science and Technology Development Project of Shandong Province （2014GGX 103019）, and Innovation and Achievement Transformation Projects of Shandong Province （2014ZZCX04206）.
文摘We demonstrate a distributed optical fiber sensing system based on the Michelson interferometer of the phase sensitive optical time domain reflectometer （q0-OTDR） for acoustic measurement. Phase, amplitude, frequency response, and location information can be directly obtained at the same time by using the passive 3 ×3 coupler demodulation. We also set an experiment and successfully restore the acoustic information. Meanwhile, our system has preliminary realized acoustic-phase sensitivity around -150 dB （re rad/μPa） in the experiment.
文摘To the Editor:Community-acquired pneumonia(CAP)is one of the most common infectious diseases,causing high morbidity and mortality.High altitudes are characterized by a hypoxic environment with low barometric pressure,increased ultraviolet radiation,and low humidity.Hypoxia can disturb normal homeostasis of the immune system,especially impairing the function of the T lymphocytes,leading to an increased susceptibility to bacterial infection.The respiratory symptoms of CAP at high altitudes are similar to that of high-altitude pulmonary edema.
基金supported by the National Natural Science Foundation of China(No.61605101)the Focus of R&D Projects of Shandong Province(No.2019GSF111065).
文摘We propose a new non-intrusive flow measurement method using the distributed feedback fiber laser(DFB-FL)as a sensor to monitor flow in the pipe.The relationship between the wavelength of the DFB-FL and the liquid flow rate in the pipeline is derived.Under the guidance of this theory,the design and test of the flow sensor is completed.The response curve is relatively flat in the frequency range of 10 Hz to 500 Hz,and the response of the flow sensor has high linearity.The flow from 0.6 m^3/h to 25.5 m^3/h is accurately measured under the energy analysis method in different frequency intervals.A minimum flow rate of 0.046 m/s is achieved.The experimental results demonstrate the feasibility of the new non-intrusive flow measurement method based on the DFB-FL and accurate measurement of small flow rates.
