BACKGROUNDParagonimiasis is a typical food-borne zoonotic disease. Hosts acquire Paragonimusinfection through the ingestion of raw or undercooked crayfish and crab.The clinical manifestations of the disease are varied...BACKGROUNDParagonimiasis is a typical food-borne zoonotic disease. Hosts acquire Paragonimusinfection through the ingestion of raw or undercooked crayfish and crab.The clinical manifestations of the disease are varied, and it is often misdiagnosedor missed. The diagnosis of paragonimiasis should be considered comprehensively.Praziquantel is the first choice for treatment, and albendazole can beused in combination with repeated courses in severe cases.CASE SUMMARYWe report a case of liver paragonimiasis that was misdiagnosed as an abscess. Thepatient presented with fatigue and poor appetite for 2 months, and was diagnosedwith liver abscess in the local hospital. After 6 months, the patient visited ourhospital because of recurrent abdominal pain and was diagnosed with liverparagonimiasis based on epidemiological history, clinical presentations, andlaboratory findings. He was treated with praziquantel (25 mg/kg) three times aday for 3 days;however, the symptoms still presented after treatment. He wastreated with oral praziquantel and albendazole for one further course. Follow-upsuggested that the treatment was effective and the symptoms improved.CONCLUSIONThe combination of albendazole and praziquantel may improve the therapeuticefficacy of paragonimiasis.展开更多
文摘BACKGROUNDParagonimiasis is a typical food-borne zoonotic disease. Hosts acquire Paragonimusinfection through the ingestion of raw or undercooked crayfish and crab.The clinical manifestations of the disease are varied, and it is often misdiagnosedor missed. The diagnosis of paragonimiasis should be considered comprehensively.Praziquantel is the first choice for treatment, and albendazole can beused in combination with repeated courses in severe cases.CASE SUMMARYWe report a case of liver paragonimiasis that was misdiagnosed as an abscess. Thepatient presented with fatigue and poor appetite for 2 months, and was diagnosedwith liver abscess in the local hospital. After 6 months, the patient visited ourhospital because of recurrent abdominal pain and was diagnosed with liverparagonimiasis based on epidemiological history, clinical presentations, andlaboratory findings. He was treated with praziquantel (25 mg/kg) three times aday for 3 days;however, the symptoms still presented after treatment. He wastreated with oral praziquantel and albendazole for one further course. Follow-upsuggested that the treatment was effective and the symptoms improved.CONCLUSIONThe combination of albendazole and praziquantel may improve the therapeuticefficacy of paragonimiasis.
