Low-threshold bistable reflection assisted by oscillating wave interaction with Kerr nonlinear medium

Owing to the enormously enhanced oscillating wave,a minute variation of the incident light intensity will give rise to a change in the dielectric constant of the Kerr nonlinear medium and lead to a bistable reflection with an ultra-low threshold intensity,which is closely related to the angle of incidence and the thickness of the Kerr nonlinear medium.The criterion for the existence of optical bistability is derived.Our bistability scheme is simple and not limited to the TM-polarization.

基于适配体传感器方法检测肿瘤外泌体相关蛋白的研究进展

外泌体是一种机体内大多数细胞分泌的直径为30~150 nm,具有脂质双层膜的微小囊泡,可以直接反映分泌细胞的生理和功能状态,参与细胞间的物质运输和信息通讯,其作为肿瘤早期诊断和治疗评估的生物标志物具有重要意义。外泌体的检测方法有很多,在这些检测方法中,适配体传感器技术以其价廉易用、响应快、灵敏度高、特异性强等特点,帮助肿瘤患者早期发现,早期获得诊断,早期治疗,提高生存率,并为愈后效果的评价提供了重要依据。常见的适配体传感器有荧光、电化学、比色法、光致发光、横向流动带、表面增强拉曼散射和表面等离子体共振适配体传感器,不同的适配体传感器具有不同的特征,文章对几种常见适配体传感器检测肿瘤外泌体的研究进展进行阐述。