Protein surface serves as an important representation of protein structure,revealing how protein interacts with other biomolecules to perform its functions.This forms the basis for pharmaceutical and fundamental biolo...Protein surface serves as an important representation of protein structure,revealing how protein interacts with other biomolecules to perform its functions.This forms the basis for pharmaceutical and fundamental biological research[1].Datadriven deep learning methods in protein surface representation face challenges of label scarcity,since labeled data are typically obtained through wet lab experiments.展开更多
基金This work was supported by the Science and Technology Innovation Plan of Shanghai Science and Technology Commission(Grant No.23S41900400)the National Natural Science Foundation of China(Grant No.62076070).
文摘Protein surface serves as an important representation of protein structure,revealing how protein interacts with other biomolecules to perform its functions.This forms the basis for pharmaceutical and fundamental biological research[1].Datadriven deep learning methods in protein surface representation face challenges of label scarcity,since labeled data are typically obtained through wet lab experiments.