Axon growth is a central event in the development and post-injury plasticity of the nervous system. Growing axons encounter a wide variety of environmental instructions. Much like traffic lights in controlling the mig...Axon growth is a central event in the development and post-injury plasticity of the nervous system. Growing axons encounter a wide variety of environmental instructions. Much like traffic lights in controlling the migrating axons, chondroitin sulfate proteoglycans （CSPGs） and heparan sulfate proteoglycans （HSPGs） often lead to ＂stop＂ and ＂go＂ growth responses in the axons, respectively. Recently, the LAR family and NgR family molecules were identified as neuronal receptors for CSPGs and HSPGs. These discoveries provided molecular tools for further study of mechanisms underlying axon growth regulation. More importantly, the identification of these proteoglycan receptors offered potential therapeutic targets for promoting post-injury axon regeneration.展开更多
The active/passive Q-switching operation of a 2 μm a-cut Tm,Ho:YAP laser was experimentally demonstrated with an acousto-optical Q–switch∕MoS_2 saturable absorber mirror. The active Q-switch laser was operated for ...The active/passive Q-switching operation of a 2 μm a-cut Tm,Ho:YAP laser was experimentally demonstrated with an acousto-optical Q–switch∕MoS_2 saturable absorber mirror. The active Q-switch laser was operated for the first time, to the best of our knowledge, with an average output power of 12.3 W and a maximum pulse energy of 10.3 mJ. The passive Q-switch laser was also the first acquired with an average output power of 3.3 W and per pulse energy of 23.31 μJ, and the beam quality factors of M_x^2 = 1.06 and M_y^2 = 1.06 were measured at the average output power of 2 W.展开更多
We demonstrated a high-power long-wave infrared laser based on a polarization beam coupling technique.An average output power at 8.3µm of 7.0 W was achieved at a maximum available pump power of 107.6 W,correspond...We demonstrated a high-power long-wave infrared laser based on a polarization beam coupling technique.An average output power at 8.3µm of 7.0 W was achieved at a maximum available pump power of 107.6 W,corresponding to an optical-to-optical conversion of 6.5%.The coupling efficiency of the polarization coupling system was calculated to be approximately 97.2%.With idler single resonance operation,a good beam quality factor of^1.8 combined with an output wavelength of 8.3µm was obtained at the maximum output power.展开更多
文摘Axon growth is a central event in the development and post-injury plasticity of the nervous system. Growing axons encounter a wide variety of environmental instructions. Much like traffic lights in controlling the migrating axons, chondroitin sulfate proteoglycans （CSPGs） and heparan sulfate proteoglycans （HSPGs） often lead to ＂stop＂ and ＂go＂ growth responses in the axons, respectively. Recently, the LAR family and NgR family molecules were identified as neuronal receptors for CSPGs and HSPGs. These discoveries provided molecular tools for further study of mechanisms underlying axon growth regulation. More importantly, the identification of these proteoglycan receptors offered potential therapeutic targets for promoting post-injury axon regeneration.
基金National Natural Science Foundation of China(NSFC)(61378029,61775053,51572053,51777046)Science Foundation for Outstanding Youths of Heilongjiang Province(JC2016016)Science Foundation for Youths of Heilongjiang Province(QC2017078)
文摘The active/passive Q-switching operation of a 2 μm a-cut Tm,Ho:YAP laser was experimentally demonstrated with an acousto-optical Q–switch∕MoS_2 saturable absorber mirror. The active Q-switch laser was operated for the first time, to the best of our knowledge, with an average output power of 12.3 W and a maximum pulse energy of 10.3 mJ. The passive Q-switch laser was also the first acquired with an average output power of 3.3 W and per pulse energy of 23.31 μJ, and the beam quality factors of M_x^2 = 1.06 and M_y^2 = 1.06 were measured at the average output power of 2 W.
基金This work was supported by the National Natural Science Foundation of China(NFSC)(Nos.61805209 and 51572053).
文摘We demonstrated a high-power long-wave infrared laser based on a polarization beam coupling technique.An average output power at 8.3µm of 7.0 W was achieved at a maximum available pump power of 107.6 W,corresponding to an optical-to-optical conversion of 6.5%.The coupling efficiency of the polarization coupling system was calculated to be approximately 97.2%.With idler single resonance operation,a good beam quality factor of^1.8 combined with an output wavelength of 8.3µm was obtained at the maximum output power.
