To improve the efficiency and correctness of the review,we aimed to continuously improve the review strategy of parenteral nutrition(PN)prescriptions.A calculation formula(CF)and an electronic prescription reviewing s...To improve the efficiency and correctness of the review,we aimed to continuously improve the review strategy of parenteral nutrition(PN)prescriptions.A calculation formula(CF)and an electronic prescription reviewing system(EPRS)were designed to improve efficiency.The improvements were divided into three periods:pre-improvement,improvement period-1(CF was used),and improvement period-2(EPRS-CF was used).A retrospective analysis for inpatients receiving PN support from January to May 2019,June to October 2019,and June to October 2020,was conducted to evaluate the defect and efficiency of the PN prescription review.Compared with the pre-improvement period,the efficiency of the PN prescription review in the CF period was improved.In addition,in the EPRS-CF period,the efficiency and correctness of the PN prescription review were remarkably increased(P<0.01).Moreover,through the verification of PN prescriptions in the EPRS-CF period,pharmacists improved the efficiency and correctness of the PN prescription review.Besides,the PDCA(plan-do-check-act)circulation method could help improve the PN reviewing process in the future.展开更多
The use of caspofungin in neonates is beyond the instructions. Therefore, a retrospective analysis was performed to investigate the hepatic safety of caspofungin during the treatment of fungal diseases in neonates. A ...The use of caspofungin in neonates is beyond the instructions. Therefore, a retrospective analysis was performed to investigate the hepatic safety of caspofungin during the treatment of fungal diseases in neonates. A retrospective analysis was conducted on 23 neonates with Candida infection who were treated or prevented with caspofungin. Among the 23 neonates treated with caspofungin, 13 cases were cured(57%), and 10 cases showed improvements(43%). In addition, there were no adverse reactions associated with drug use, such as gastrointestinal tract, thrombocytopenia, and liver function damage. In summary, caspofungin achieved good results in the treatment or prevention of Candida infection in neonates, and no severe adverse reactions closely related to its use were found. However, the economy and safety of antifungal drugs should be considered in clinical practice for reasonable use.展开更多
基金Science and Technology Project of Jiangxi Health Commission(Grant No.20185191)。
文摘To improve the efficiency and correctness of the review,we aimed to continuously improve the review strategy of parenteral nutrition(PN)prescriptions.A calculation formula(CF)and an electronic prescription reviewing system(EPRS)were designed to improve efficiency.The improvements were divided into three periods:pre-improvement,improvement period-1(CF was used),and improvement period-2(EPRS-CF was used).A retrospective analysis for inpatients receiving PN support from January to May 2019,June to October 2019,and June to October 2020,was conducted to evaluate the defect and efficiency of the PN prescription review.Compared with the pre-improvement period,the efficiency of the PN prescription review in the CF period was improved.In addition,in the EPRS-CF period,the efficiency and correctness of the PN prescription review were remarkably increased(P<0.01).Moreover,through the verification of PN prescriptions in the EPRS-CF period,pharmacists improved the efficiency and correctness of the PN prescription review.Besides,the PDCA(plan-do-check-act)circulation method could help improve the PN reviewing process in the future.
文摘The use of caspofungin in neonates is beyond the instructions. Therefore, a retrospective analysis was performed to investigate the hepatic safety of caspofungin during the treatment of fungal diseases in neonates. A retrospective analysis was conducted on 23 neonates with Candida infection who were treated or prevented with caspofungin. Among the 23 neonates treated with caspofungin, 13 cases were cured(57%), and 10 cases showed improvements(43%). In addition, there were no adverse reactions associated with drug use, such as gastrointestinal tract, thrombocytopenia, and liver function damage. In summary, caspofungin achieved good results in the treatment or prevention of Candida infection in neonates, and no severe adverse reactions closely related to its use were found. However, the economy and safety of antifungal drugs should be considered in clinical practice for reasonable use.
