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Feasibility and utility of intraoperative optical coherence tomography during vitreoretinal surgery:A 4-year report in Chinese population 被引量:2
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作者 Jiwei Tao Huan chen +5 位作者 Jiafeng Yu Dan cheng yiqi chen Jianbo Mao Jia Fang Lijun Shen 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2021年第1期46-55,共10页
The objective is to introduce the application of intraoperative optical coherence tomography(iOCT)in pars plana vitrectomy(PPV)for various vitreoretinal diseases,and to report the 4-year assessment of feasibility and ... The objective is to introduce the application of intraoperative optical coherence tomography(iOCT)in pars plana vitrectomy(PPV)for various vitreoretinal diseases,and to report the 4-year assessment of feasibility and utility in Chinese population.We reported a retrospective case series of patients who underwent PPV and iOCT scan at Eye Hospital of Wenzhou Medical University from January 2016 to January 2020.Clinical characteristics were documented before operation,and we intraoperatively recorded the time and results of iOCT scanning,specific surgical maneuvers performed,the consistency with the planned strategies before surgery,the type of OCT images obtained,and adverse events(AEs).The surgeon feedback was collected to evaluate the utility of iOCT during surgery.In total 339 eyes successfully completed iOCT scan,with an average scanning time of 3.54±2.3 min,including 59 cases of idiopathic macular hole(iMH),134 cases of idiopathic epiretinal membrane(iERM),33 cases of lamellar macular hole(LMH),40 cases of high myopic maculopathy,13 cases of vitreous macular traction(VMT),60 cases of dense vitreous hemorrhage(VH).The iOCT findings were not consistent with exami-nation under the operating microscope in 49 cases(14.5%),including 29 cases(8.6%)which changed the operation strategies during surgery.The Hole-door phenomenon arose in 20 cases(33.9%)of iMH and 3 cases(25%)of high myopic MH after ILMs peeling.Moreover,the residue ERM was observed in nine cases(6.7%)of iERM and two cases(14.3%)in high myopic ERM after ILMs peeling.Some new surgical methods could also be confirmed using iOCT.The ap-plication of iOCT has a significant clinical functionality in vitreoretinal surgery,providing the surgeon with a new surgical understanding,guiding the selection of a more reasonable operative procedure during surgery,predicting postoperative recovery and improving postoperative outcomes. 展开更多
关键词 Intraoperative optical coherence tomography vitreoretinal diseases pars plana vit-rectomy surgical guidance
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Development Prospect of Aromatherapy Industry in Yunnan Province
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作者 Ziyun PENG Dantong LI +3 位作者 Rui chen Min QIAN yiqi chen Hongjun YANG 《Asian Agricultural Research》 2014年第1期42-44,48,共4页
This paper firstly introduced domestic and foreign supply of products processed by aromatherapy plant. On the basis of predicting market demand of aromatherapy plant,it analyzed current development situation of the pl... This paper firstly introduced domestic and foreign supply of products processed by aromatherapy plant. On the basis of predicting market demand of aromatherapy plant,it analyzed current development situation of the plant in Yunnan Province. It arrived at the conclusion that the industry has broad market prospect. Then,it analyzed competitive advantages and risk factors of aromatherapy plant in Yunnan Province. There are climate,location and price advantages,but due to lack of product standard,it is difficult to guarantee quality,and there are certain market risks. Finally,it put forward recommendations for development of aromatherapy industry:( 1) taking full advantage of preferential policies to set up leading enterprises and realize radiated development;( 2) bringing into play of resource advantages and introducing capitals and technologies;( 3) Fostering market and driving the industrial development. 展开更多
关键词 AROMATHERAPY PLANT Industrial DEVELOPMENT PROSPECT
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Precise and Controllable Assembly of Block Copolymers
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作者 Bixin Jin yiqi chen +1 位作者 Yunjun Luo Xiaoyu Li 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2023年第1期93-110,共18页
With the development of nanotechnology,the precise synthesis of nanoparticles with nicely-defined dimensions and structures has been well-developed,and the functionalization and subsequent applications of the resultan... With the development of nanotechnology,the precise synthesis of nanoparticles with nicely-defined dimensions and structures has been well-developed,and the functionalization and subsequent applications of the resultant nanostructures are becoming increas-ingly important.Comparing to inorganic nanoparticles,the nanostructures based on soft matters,especially block copolymer as-semblies,are much lower in cost,easier to fabricate and richer in morphology.However,the dimensional control over the block co-polymer assemblies is not as easy.Only in recent decade,with the discovery of living Crystallization-Driven Self-Assembly(CDSA)by Manners and Winnik,researchers become able to precisely tune the sizes of block copolymer assemblies in a relatively wide range.This discovery has inspired tremendous research effort in the self-assembly field,and considerable progress has been made recently.This review summarizes the main progress in the precise and controllable self-assembly field in the past five years,and is mostly fo-cused on four aspects,including in-depth understanding of the assembly methods,extension of this method to two-dimensional nanostructures,utilization of this method to fabricate hierarchical structures,and the potential applications of these well-defined nanostructures.We hope not only to make a periodic systematic summary of previous studies,but also to provide some useful thinking for the future development of this field. 展开更多
关键词 NANOSTRUCTURES Micelles NANOTECHNOLOGY SELF-ASSEMBLY Precise assembly
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早产儿出生后早期屈光状态及其影响因素 被引量:12
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作者 毛剑波 劳吉梦 +6 位作者 刘忱怡 吴明远 侯立杰 吕喆 祝晨婷 陈亦棋 沈丽君 《中华眼视光学与视觉科学杂志》 CAS CSCD 2018年第10期588-592,共5页
目的:探讨早产儿矫正胎龄32~40周的屈光状态,评估早产儿屈光发育与出生体质量、出生孕龄以及早产儿视网膜病变(ROP)的相关性。方法:选取2016年3-12月在浙江大学医学院附属妇产科医院NICU及温州医科大学附属眼视光医院杭州院区接受ROP筛... 目的:探讨早产儿矫正胎龄32~40周的屈光状态,评估早产儿屈光发育与出生体质量、出生孕龄以及早产儿视网膜病变(ROP)的相关性。方法:选取2016年3-12月在浙江大学医学院附属妇产科医院NICU及温州医科大学附属眼视光医院杭州院区接受ROP筛查的早产儿为研究对象,对早产儿屈光状态以及相关影响因素进行前瞻性研究。在矫正胎龄32~40周时右眼行睫状肌麻痹下检影验光,再进行ROP筛查并记录。记录早产儿的基本信息如出生体质量、出生孕龄、性别、吸氧史等以及接受检查时的矫正胎龄并进行统计分析。采用Pearson相关性分析来研究等效球镜度(SE)分别与出生体质量、出生孕龄、矫正胎龄之间的关系。采用独立样本t检验来比较矫正胎龄40周时有无ROP的SE差异。结果:共333例早产儿纳入研究,其中男175例,女158例。收集屈光记录542份。早产儿出生孕龄为26~36(31.3±2.1)周,出生体质量为740~3 390(1 643±418)g。SE随着早产儿矫正胎龄的增大而增大(r=0.455,P<0.001)。早产儿出生后4~5周,出生孕龄(r=0.373,P<0.001)、出生体质量(r=0.345,P<0.001)均和SE呈正相关。至早产儿矫正胎龄40周时,SE与出生体质量呈正相关(r=0.197,P=0.021),与出生孕龄无相关性,合并ROP的早产儿相比没有ROP的有较低的SE(t=2.225,P=0.028)。结论:早产儿在出生后早期矫正胎龄32~40周时,屈光状态向远视发展。在出生后4~5周,出生孕龄小或出生体质量低的早产儿更偏向于近视状态。至矫正胎龄40周时,有ROP或者低出生体质量的早产儿有较低的SE,而与出生孕龄无相关性。 展开更多
关键词 屈光状态 影响因素 早产儿
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玻璃体切割联合内界膜剥除和空气填充治疗特发性黄斑裂孔 被引量:10
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作者 陶继伟 陈焕 +4 位作者 沈丽君 俞雪婷 陈亦棋 毛剑波 林丽 《中华眼视光学与视觉科学杂志》 CAS CSCD 2019年第6期439-443,共5页
目的:观察玻璃体切割手术联合内界膜剥除和空气填充治疗特发性全层黄斑裂孔(IMH)的疗效。方法:回顾性系列病例研究。收集2017年1月至2018年1月在温州医科大学附属眼视光医院杭州院区确诊并行玻璃体切割术治疗的连续IMH患者32例(32眼),年... 目的:观察玻璃体切割手术联合内界膜剥除和空气填充治疗特发性全层黄斑裂孔(IMH)的疗效。方法:回顾性系列病例研究。收集2017年1月至2018年1月在温州医科大学附属眼视光医院杭州院区确诊并行玻璃体切割术治疗的连续IMH患者32例(32眼),年龄47~78(60.7±12.2)岁,其中男9例,女23例。术中均采用消毒空气进行眼内填充。根据术后早期首次光学相干断层扫描(OCT)提示裂孔是否闭合分为闭合组和未闭合组,对2组患者术前、术后的最佳矫正视力(BCVA)、裂孔直径等采用秩和检验及独立样本t检验进行比较;2组患者裂孔闭合率及外界膜和光感受器连续性比较采用卡方检验。结果:术后末次随访时所有患者LogMARBCVA为0.40(0.30,0.73),较术前[0.80(0.70,1.00)]明显提高(Z=-3.439,P<0.001)。术后早期OCT扫描显示24例黄斑裂孔闭合,8例黄斑裂孔未闭合,予再次玻璃体腔空气填充治疗,术后1个月及术后末次随访所有患者黄斑裂孔均闭合。术后1个月OCT扫描外界膜(ELM)连续的患者有16例,无一例椭圆体层(EZ)连续;末次随访时18例患者ELM连续,6例EZ连续。未闭合组术前黄斑裂孔直径为(532±104)μm,明显大于闭合组黄斑裂孔直径[(352±180)μm](t=-2.656,P=0.013)。闭合组术后1个月ELM均存在连续性,末次随访ELM和EZ连续性均高于未闭合组,2组差异具有显著的统计学意义(χ^2=4.23,P=0.040;χ^2=3.89,P=0.048)。结论:玻璃体切割联合ILM剥除和空气填充治疗IMH具有较好的疗效,对于大于400μm的裂孔部分患者需要再次玻璃体腔空气填充治疗。 展开更多
关键词 黄斑裂孔 空气填充 玻璃体切割
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玻璃体切割联合内界膜剥除治疗糖尿病性黄斑水肿 被引量:8
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作者 赵士鑫 吴韩飞 +3 位作者 沈丽君 毛剑波 陈亦棋 陶继伟 《中华眼视光学与视觉科学杂志》 CAS CSCD 2019年第6期433-438,共6页
目的:评估玻璃体切割联合内界膜剥除对糖尿病性黄斑水肿(DME)的疗效。方法:回顾性病例对照研究。2014年6月至2017年1月间因糖尿病视网膜病变合并玻璃体积血或增殖病变于温州医科大学附属眼视光医院杭州院区行玻璃体切割手术治疗,且术前... 目的:评估玻璃体切割联合内界膜剥除对糖尿病性黄斑水肿(DME)的疗效。方法:回顾性病例对照研究。2014年6月至2017年1月间因糖尿病视网膜病变合并玻璃体积血或增殖病变于温州医科大学附属眼视光医院杭州院区行玻璃体切割手术治疗,且术前或术中经光学相干断层扫描(OCT)检查确诊合并DME的患者31例(33眼)纳入研究。16例(18眼)术中联合内界膜剥除作为剥膜组,15例(15眼)仅接受玻璃体切割手术治疗者作为对照组。所有手术均由同一医师主刀完成。术后1、3个月随访时复查OCT,对比观察黄斑中心厚度(CMT)和视力的术后变化情况。随访中CMT和最佳矫正视力(BCVA)比较采用重复测量方差分析,组间CMT和BCVA比较采用独立样本t检验。结果:手术前,手术后1、3个月2组间比较LogMAR视力总体差异有统计学意义(F=15.93,P<0.001)。术后1个月时剥膜组BCVA高于对照组(t=2.55,P=0.02),但术后3个月时2组间差异无统计学意义(t=0.82,P=0.42)。手术前,手术后1、3个月CMT总体差异无统计学意义(F=2.85,P=0.065)。术后1、3个月时,剥膜组的CMT均低于对照组,2组间差异均有统计学意义(t=2.24,P=0.03;t=3.79,P=0.001)。术后1个月时,剥膜组有效(与术前比CMT减少20%以上)、无效(变化不超过20%)及恶化(增厚超过20%)的例数分别为8、6、4例,术后3个月时则分别为11、5、2例,与对照组相比,术后1个月时组间差异无统计学意义(Z=-1.687,P=0.092),术后3个月时剥膜组DME改善有效比例明显高于对照组,组间差异有统计学意义(Z=-2.177,P=0.029)。结论:对于非牵拉性DME,内界膜剥除有助于术后早期DME消退。 展开更多
关键词 糖尿病性黄斑水肿 玻璃体切割术 内界膜
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术中OCT在致密玻璃体积血玻璃体切割手术中的应用 被引量:6
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作者 陶继伟 褚梦琪 +4 位作者 王奇骅 陈亦棋 赵士鑫 林晶晶 沈丽君 《中华眼视光学与视觉科学杂志》 CAS CSCD 2017年第11期686-690,共5页
目的:评估术中光学相干断层扫描(iOCT)在致密玻璃体积血手术中的临床应用价值。方法:回顾性系列病例研究。收集2015年6月至2016年9月在温州医科大学附属眼视光医院采取玻璃体切割手术治疗的致密玻璃体积血患者共24例(24眼),其中... 目的:评估术中光学相干断层扫描(iOCT)在致密玻璃体积血手术中的临床应用价值。方法:回顾性系列病例研究。收集2015年6月至2016年9月在温州医科大学附属眼视光医院采取玻璃体切割手术治疗的致密玻璃体积血患者共24例(24眼),其中男14例,女10例,平均年龄(62.3±16.6)岁。所有患者术中清除致密出血后行iOCT检查,了解黄斑情况。记录iOCT检查时间及结果,对比iOCT结果与术者显微镜下观察判断是否一致,观察iOCT结果是否对手术治疗策略产生影响,以及与检查相关的并发症发生情况。结果:纳入的24例病例中,糖尿病视网膜病变15例,视网膜静脉阻塞4例,视网膜裂孔1例,息肉状脉络膜血管病变2例,大动脉瘤1例,不明原因新生血管1例。iOCT结果提示10例患者术中黄斑区结构正常,14例结构异常:其中黄斑水肿8例,黄斑前膜2例,黄斑前膜伴水肿1例,黄斑萎缩2例,黄斑板层裂孔1例。iOCT检查结果与手术者手术显微镜观察结果不一致为6例;因iOCT结果而改变手术策略的有4例。未见与检查相关的眼内炎等并发症发生。结论:iOCT在致密玻璃体积血患者玻璃体切割术中的应用可给手术者提供显微镜下无法察觉的黄斑区异常改变,指导术者选择更为合理的手术方式。 展开更多
关键词 光学相干断层扫描 致密玻璃体积血 手术指导
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A new PM_(2.5)-based CADR method to measure air infiltration rate of buildings 被引量:2
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作者 Cong Liu Siyu Ji +3 位作者 Fengjiao Zhou Qingbin Lin yiqi chen Xiaoliang Shao 《Building Simulation》 SCIE EI CSCD 2021年第3期693-700,共8页
Air infiltration is an important way to exchange indoor air with outdoors.It significantly impacts energy consumption and air quality of buildings.Fine particles(PM_(2.5))in the outdoor atmosphere environment are a po... Air infiltration is an important way to exchange indoor air with outdoors.It significantly impacts energy consumption and air quality of buildings.Fine particles(PM_(2.5))in the outdoor atmosphere environment are a potential natural tracer for the measurement of air infiltration rate,especially in the long term field measurement.In this study,a PM_(2.5)-based method,named as CADR(clean air delivery rate)method,is developed to supplement traditional tracer gas method in order to make routine measurement in realistic environments possible and convenient.An air cleaner is installed indoors to reduce indoor PM_(2.5) concentration.Air infiltration is determined by fitting a model to the decreasing concentration data.Comparison with CO_(2) decay method in four different indoor environments gives a normalized mean error of 19%and a correlation coefficient of 0.80 for this method.This justifies the CADR method as a feasible option to measure air infiltration rate.Although subject to several constraints,the proposed method would facilitate field measurement under realistic conditions by being combined with current tracer gas methods. 展开更多
关键词 natural ventilation outdoor-indoor-connection HAZE FORMALDEHYDE VOCs EXPOSURE
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早产儿出生后早期屈光系统发育及其影响因素 被引量:3
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作者 劳吉梦 毛剑波 +6 位作者 朱琳 邵伊润 张彩云 俞雪婷 吕喆 陈亦棋 沈丽君 《中华眼视光学与视觉科学杂志》 CAS CSCD 2020年第8期602-606,共5页
目的:探讨早产儿矫正胎龄32~40周的屈光系统发育情况,评估早产儿眼轴长度与出生体质量及出生孕龄的相关性。方法:系列病例研究。选取2018年3─12月在浙江大学医学院附属妇产科医院以及温州医科大学附属眼视光医院接受早产儿视网膜病变... 目的:探讨早产儿矫正胎龄32~40周的屈光系统发育情况,评估早产儿眼轴长度与出生体质量及出生孕龄的相关性。方法:系列病例研究。选取2018年3─12月在浙江大学医学院附属妇产科医院以及温州医科大学附属眼视光医院接受早产儿视网膜病变筛查的早产儿为研究对象,在矫正胎龄32~40周时右眼行A超检查并记录,得到前房深度、晶状体厚度、玻璃体长度、眼轴长度等数据。记录早产儿的出生体质量、出生孕龄及接受检查时的矫正胎龄。分别根据出生孕龄(出生孕龄<30周,出生孕龄≥30周)及出生体质量(出生体质量<1500 g,出生体质量≥1500 g)对早产儿进行分组并评估其与眼轴长度的相关性。采用Pearson相关性分析研究屈光系统参数与矫正胎龄的关系,2组间眼轴长度的比较采用独立样本t检验。结果:共496例早产儿纳入研究,收集屈光系统参数1385次。前房深度(r=0.384,P<0.001),晶状体厚度(r=0.295,P<0.001),玻璃体长度(r=0.723,P<0.001),眼轴长度(r=0.782,P<0.001)均与矫正胎龄呈正相关。出生孕龄<30周以及出生孕龄≥30周的早产儿眼轴差异无统计学意义。出生体质量<1500 g的早产儿较出生体质量≥1500 g的早产儿在矫正胎龄38~40周时眼轴更短,差异有统计学意义(t=2.195,P=0.030;t=2.504,P=0.015;t=1.989,P=0.048)。结论:早产儿出生后早期,出生孕龄对眼轴影响不大,极低出生体质量早产儿有较短的眼轴。 展开更多
关键词 眼球发育 出生体重 孕龄 婴儿 早产
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Monitoring and identifying pendant droplets in microbottle resonators 被引量:2
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作者 Zijie Wang Xiaobei Zhang +7 位作者 Qi Zhang yiqi chen Yong Yang Yang Yu Yang Wang Yanhua Dong Yi Huang Tingyun Wang 《Photonics Research》 SCIE EI CAS CSCD 2022年第3期662-667,共6页
Optofluidic resonators are capable of characterizing various fluidic media.Here,we propose an optofluidic microbottle resonator(OFMBR)that is applied to generate pendant droplets,whose maximum mass is related to the l... Optofluidic resonators are capable of characterizing various fluidic media.Here,we propose an optofluidic microbottle resonator(OFMBR)that is applied to generate pendant droplets,whose maximum mass is related to the liquid surface tension.Mass and type of droplets forming along the OFMBR stem can be monitored in real time by spectrum variation.As a pendant droplet grows,increased droplet gravity introduces a decreased coupling gap and compressive force between the tapered fiber and OFMBR,leading to a resonance wavelength shift.The operation mechanism of the proposed sensors is validated by theoretical simulation and experimental results.From the experimental spectra,a liquid mass sensor with maximum sensitivity of−3.34pm/mg is obtained,and distilled water and alcohol can be identified.This scheme provides a new thread for droplet generation as well as fluidic properties characterization. 展开更多
关键词 MECHANISM COUPLING ALCOHOL
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Contribution of Winter SSTA in the Tropical Eastern Pacific to Changes of Tropical Cyclone Precipitation over Southeast China 被引量:1
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作者 Xianghua WU Qihao ZHU +4 位作者 Chao WANG Yue ZHOU yiqi chen Xintong TIAN Yajie HUA 《Journal of Meteorological Research》 SCIE CSCD 2022年第2期282-291,共10页
Tropical cyclone precipitation(TCP)accounts for 10%-40%of the boreal summer precipitation that occurs over Southeast China(SEC),causing flood disasters and serious damage.On the decadal scale,TCP increases significant... Tropical cyclone precipitation(TCP)accounts for 10%-40%of the boreal summer precipitation that occurs over Southeast China(SEC),causing flood disasters and serious damage.On the decadal scale,TCP increases significantly in SEC while TC frequency decreases in the western North Pacific(WNP)during 1980-2019.Therefore,variations in TCP and the corresponding physical mechanism are investigated in this study.First,an empirical statistical method is introduced to quantify the TCP amount based on accumulated cyclone energy(ACE)and TC frequency with the TCP anomaly decomposed into three items(rainfall frequency,rainfall intensity,and nonlinear item).ACE,as the integration of TC intensity and frequency,is a more effective index than TC frequency for depicting the characteristics of TCP because the contribution of rainfall frequency represented by ACE is higher than that of TC frequency.Then,the physical mechanism affecting the WNP TC activities and TCP in SEC are inspected.Positive sea surface temperature anomaly(SSTA)over the tropical eastern Pacific(TEP)in winter can trigger variations of air-sea interaction over the tropical Pacific,including low-level divergent winds,mid-tropospheric descent flows,high-level convergent winds coupled with negative anomalies of vorticity and humidity over the tropical western Pacific(TWP)in the next summer.These dynamic conditions provide unfavorable environments for TC activities in the WNP and constrain TCP in SEC.Furthermore,more significantly negative SSTA events in the TEP facilitate enhanced ACE along with positive relative vorticity,relative humidity,and upwelling vertical winds anomalies over the coast of SEC after 1998,which is a reasonable explanation for the increasing TCP in SEC. 展开更多
关键词 tropical cyclone precipitation accumulated cyclone energy sea surface temperature anomaly air–sea interaction
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