期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
发育中的小鼠海马星形胶质细胞功能性合胞体的产生
1
作者 杜一星(编译) 《神经损伤与功能重建》 2023年第3期F0003-F0003,共1页
越来越多的证据表明星形胶质细胞在脑功能中起着等电位合胞体的作用。原生质星形胶质细胞通过以下方面获得了这种在功能上超越单细胞水平的能力:进化为海绵状形态、细胞质连接成合胞体,以及表达高密度的K+电导。然而,围生期新生星形胶... 越来越多的证据表明星形胶质细胞在脑功能中起着等电位合胞体的作用。原生质星形胶质细胞通过以下方面获得了这种在功能上超越单细胞水平的能力:进化为海绵状形态、细胞质连接成合胞体,以及表达高密度的K+电导。然而,围生期新生星形胶质细胞中并不存在这些细胞/功能特征。由此我们提出了一个基本问题,即在发育中的大脑中功能性合胞体是何时形成的。我们的结果表明,海马CA1区的星形胶质细胞的海绵状形态及其空间组织均在出生后第15天达到稳定水平。在功能上,星形胶质细胞在出生11 d即开始统一表达成熟水平的被动K+电导。我们使用合胞体等电位来监测星形胶质细胞合胞体的成熟。在出生1 d小鼠的非偶联星形胶质细胞中,用Na+电极溶液([Na+]p)替代内源性K+导致了生理膜电位(VM)以及Goldman-Hodgkin-Katz(GHK)方程预测的外向K+电导的完全消除。随着发育过程中更多的星形胶质细胞通过缝隙连接相互耦合,[Na+]p诱导的生理VM和向外的K+电导的损失逐渐由邻近的星形胶质细胞所补偿。到出生后15 d,在所有[Na+]p记录的星形胶质细胞中均出现稳定建立的合胞体等电位(-73 mV)和完全补偿的外向K+电导。因此,鉴于单个合胞体在解剖和功能上用于合胞体内K+平衡功能建立的发育时间框架,星形胶质细胞合胞体在出生15 d的小鼠海马体中可全面行使其功能。 展开更多
关键词 K+电导 星形胶质细胞 电耦合 缝隙连接 合胞体等电位
下载PDF
Revision of the Conodont Mockina slovakensis and Its Paleogeographic Implications for the Upper Triassic Intraplatform Basins of the Alps 被引量:2
2
作者 yixing du Viktor Karadi +3 位作者 Guido Roghi Maurizio Ponton Andrea Cozzi Manuel Rigo 《Journal of Earth Science》 SCIE CAS CSCD 2021年第3期657-666,共10页
Mockina slovakensis,thought to have evolved from Epigondolella praeslovakensis,is an important species of the Norian(Upper Triassic),generally considered as the representative of the uppermost Alaunian to upper Sevati... Mockina slovakensis,thought to have evolved from Epigondolella praeslovakensis,is an important species of the Norian(Upper Triassic),generally considered as the representative of the uppermost Alaunian to upper Sevatian in the Tethys.The previous description of M.slovakensis was incomplete,thus has led to some misidentifications.We thus update the description of M.slovakensis and discuss its comparisons and occurrence based on the new conodont investigations in Dolomia di Forni and the data from previous literatures.The conodont assemblage in the succession of Dolomia di Forni is dominated by M.slovakensis,along with rare M.postera and E.praeslovakensis.We described two morphotypes of M.slovakensis(morphotypes A and B),on the basis of shape of the lateral profile.These two morphotypes can also be observed in the E.praeslovakensis.Moreover,M.slovakensis is usually documented as almost monospecific conodont association in intraplatform basins,thus its paleogeographic implications are also discussed. 展开更多
关键词 Mockina CONODONT MORPHOTYPE intraplatform basin
原文传递
Evolutionary Process from Mockina bidentata to Parvigondolella andrusovi:Evidence from the Pizzo Mondello Section,Sicily,Italy 被引量:1
3
作者 yixing du Tetsuji Onoue +2 位作者 Viktor Karadi Ian S.Williams Manuel Rigo 《Journal of Earth Science》 SCIE CAS CSCD 2021年第3期667-676,共10页
During their last phase of evolution,the pectiniform conodont elements manifested an evident trend of simplification and miniaturization.This phase started from the late Norian(Sevatian)in the Late Triassic and the ev... During their last phase of evolution,the pectiniform conodont elements manifested an evident trend of simplification and miniaturization.This phase started from the late Norian(Sevatian)in the Late Triassic and the evolutionary process of genus Mockina to Parvigondolella,in particular between Mockina bidentata and Parvigondolella andrusovi,is one of the most significant examples.Parvigondolella has been reported worldwide since it was first described in the early 1970s.However,it has recently been suggested that genus Parvigondolella is an ecostratigraphic morphotype of genus Mockina,and thus a phenotype controlled by the environmental conditions,and not an independent taxon.In the Pizzo Mondello Section(Sicily,Italy),transitional forms between M.bidentata and P.andrusovi have been found at different evolutionary stages.We have investigated the oceanic conditions at the time by using redox-sensitive elements(Mn,Fe,V,Cr,and Ni)and seawater temperatures from biogenetic δ^(18)Ophos to understand the possible environmental influences on the phylogenetic evolution between Mockina and Parvigondolella.The geochemical and isotope analyses indicate that the redox condition and temperature were stable during the evolution of genus Parvigondolella in Pizzo Mondello,confirming that genus Parvigondolella is a real taxon and not a phenotype.A new conodont species named Parvigondolella ciarapicae n.sp.is described here for the first time. 展开更多
关键词 CONODONT Late Triassic evolution oxygen isotope GEOCHEMISTRY
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部