We evaluated the prevalence of use of complementary and alternative medicine (CAM), as well as the transitional nature of its use, before and after radical prostatectomy in Japa-nese patients with localized prostate c...We evaluated the prevalence of use of complementary and alternative medicine (CAM), as well as the transitional nature of its use, before and after radical prostatectomy in Japa-nese patients with localized prostate cancer. Methods: We enrolled 376 patients, who an-swered a self-administered questionnaire on CAM use, psychological health locus of control (HLC), and general-health-related quality of life (GHQL). Detailed information regarding CAM use according to the transtheoretical model, and the time at initiation and abandonment of CAM use were assessed. Medical information was also extracted from patient charts. Results: 45.7% of patients belonged to the “precontem-plation” stage, 29.8% to the “contemplation” stage, 1.9% to the “preparation” stage, 14.4% to the “action” stage, and 8.2% to the “relapse” stage. Although patient age and educational status had a significant impact on stage of CAM use, HLC and GHQL were not associated with them. The time-course of prevalence of CAM use during follow-up was divided into three phases: “initial,” “rapid-increase,” and “main-tenance”. Conclusions: Among patients under-going radical prostatectomy, non-users can be classified into several behavioral stages, while users do not use CAM constantly during fol-low-up.展开更多
Background Our previous studies have demonstrated potent oncolysis efficacy of the E1A, E1B double-restricted replication-competent oncolytic adenovirus AxdAdB-3 for treatment of bladder cancer. Here, we reported the ...Background Our previous studies have demonstrated potent oncolysis efficacy of the E1A, E1B double-restricted replication-competent oncolytic adenovirus AxdAdB-3 for treatment of bladder cancer. Here, we reported the feasibility and efficacy of AxdAdB-3 alone, or in combination with gemcitabine for treating renal cell carcinoma.展开更多
文摘We evaluated the prevalence of use of complementary and alternative medicine (CAM), as well as the transitional nature of its use, before and after radical prostatectomy in Japa-nese patients with localized prostate cancer. Methods: We enrolled 376 patients, who an-swered a self-administered questionnaire on CAM use, psychological health locus of control (HLC), and general-health-related quality of life (GHQL). Detailed information regarding CAM use according to the transtheoretical model, and the time at initiation and abandonment of CAM use were assessed. Medical information was also extracted from patient charts. Results: 45.7% of patients belonged to the “precontem-plation” stage, 29.8% to the “contemplation” stage, 1.9% to the “preparation” stage, 14.4% to the “action” stage, and 8.2% to the “relapse” stage. Although patient age and educational status had a significant impact on stage of CAM use, HLC and GHQL were not associated with them. The time-course of prevalence of CAM use during follow-up was divided into three phases: “initial,” “rapid-increase,” and “main-tenance”. Conclusions: Among patients under-going radical prostatectomy, non-users can be classified into several behavioral stages, while users do not use CAM constantly during fol-low-up.
文摘Background Our previous studies have demonstrated potent oncolysis efficacy of the E1A, E1B double-restricted replication-competent oncolytic adenovirus AxdAdB-3 for treatment of bladder cancer. Here, we reported the feasibility and efficacy of AxdAdB-3 alone, or in combination with gemcitabine for treating renal cell carcinoma.
