To the Editor:Idiopathic cough is associated with laryngeal hypersensitivity and chronic pain syndromes.Idiopathic cough can be diagnosed when patients have no cause of chronic cough after treatment of cough.Patients ...To the Editor:Idiopathic cough is associated with laryngeal hypersensitivity and chronic pain syndromes.Idiopathic cough can be diagnosed when patients have no cause of chronic cough after treatment of cough.Patients with chronic cough experience impaired quality of life(QOL),interruption of daily activity,and depression.Therefore,better approaches to refractory chronic cough areneeded.展开更多
To the Editor:Optic neuritis(ON)usually ends with one episode,but recurs in 3%to 5%of patients.Among recurrent patients,those that emerge negative from multiple sclerosis or neuromyelitis optica(NMO)workup are diagnos...To the Editor:Optic neuritis(ON)usually ends with one episode,but recurs in 3%to 5%of patients.Among recurrent patients,those that emerge negative from multiple sclerosis or neuromyelitis optica(NMO)workup are diagnosed with chronic relapsing inflammatory optic neuropathy(CRION).This disease group,first named by Kidd et al,[1]refers to a clinical situation in which inflammatory optic nerve inflammation on both sides occurs repeatedly and worsens when steroids or immu-nosuppressants are discontinued.Early diagnosis is important in this group because the risk of blindness is significant,and as such,treatment is focused on preserving vision.However,because a significant number of CRION patients suffer from ocular pain,alleviation of pain should not be overlooked.展开更多
文摘To the Editor:Idiopathic cough is associated with laryngeal hypersensitivity and chronic pain syndromes.Idiopathic cough can be diagnosed when patients have no cause of chronic cough after treatment of cough.Patients with chronic cough experience impaired quality of life(QOL),interruption of daily activity,and depression.Therefore,better approaches to refractory chronic cough areneeded.
文摘To the Editor:Optic neuritis(ON)usually ends with one episode,but recurs in 3%to 5%of patients.Among recurrent patients,those that emerge negative from multiple sclerosis or neuromyelitis optica(NMO)workup are diagnosed with chronic relapsing inflammatory optic neuropathy(CRION).This disease group,first named by Kidd et al,[1]refers to a clinical situation in which inflammatory optic nerve inflammation on both sides occurs repeatedly and worsens when steroids or immu-nosuppressants are discontinued.Early diagnosis is important in this group because the risk of blindness is significant,and as such,treatment is focused on preserving vision.However,because a significant number of CRION patients suffer from ocular pain,alleviation of pain should not be overlooked.