新型冠状病毒肺炎疫情期间眼外伤流行病学特点分析

目的:分析新型冠状病毒肺炎疫情期间眼外伤入院者疾病谱变化趋势及流行病学特点。方法:回顾性病例分析。收集郑州大学第一附属医院眼科入院治疗的眼外伤者876例905眼,其中对照组(2019-01/06)545例565眼,研究组(2020-01/06)331例340眼。比较两组患者年龄、性别、受伤地点、受伤原因、居住地、受伤类型等信息。结果:研究组眼外伤住院人数较对照组减少39.3%,对照组和研究组年龄均呈双峰样分布,分别为0~10岁(20.55%,21.45%)和41~50岁(17.98%,19.03%)占比最高,两组年龄分布无差异(P=0.907)。对照组和研究组均以男性为主,占比80.37%,83.69%(P=0.219)。研究组居家受伤比例(28.40%)高于对照组(11.38%)(P<0.001)。研究组机械性眼外伤占比(98.19%)高于对照组(95.60%)(P=0.041),开放性眼外伤占比(85.54%)高于对照组(76.58%)(P=0.001),无光感者占比(18.86%)高于对照组(9.53%)(P<0.001)。结论:新型冠状病毒肺炎疫情期间,眼外伤住院患者显著减少,机械性眼外伤是主要眼外伤类型,在流行病暴发期间,仍应加强眼外伤的防护意识。

0.005%阿托品滴眼液控制低度近视儿童近视进展的安全性及有效性

目的:观察低度近视儿童应用质量分数0.005%阿托品滴眼液控制近视进展的安全性及有效性。方法:前瞻性对照研究。116例116眼低度近视儿童根据受试者和监护人意愿分为两组。阿托品(试验)组:58例58眼近视儿童配戴全矫单焦框架眼镜,同时睡前双眼各点1滴质量分数0.005%的阿托品滴眼液。框架镜(对照)组:58例58眼近视儿童仅配戴全矫单焦框架眼镜。用药前及用药后每4mo复查一次,共随访12mo,观察两组近视等效球镜度、眼轴长度、瞳孔直径和调节幅度的变化情况及试验组的不适症状。结果:随访1a后,两组的近视等效球镜度和眼轴长度治疗前后均有差异(P<0.05);两组间近视等效球镜屈光度增加量无差异(P>0.05);两组间眼轴长度增加量有微小差异,但差异无统计学意义(P>0.05);两组的瞳孔直径增加量有差异(P<0.05);两组的调节幅度下降量有差异(P<0.01)。试验组不适症状:用药初期6眼(10.3%)出现畏光,其中4眼用药2wk后畏光消失,余2眼4wk后消失。无视近模糊、过敏等其它不适症状。结论:低度近视儿童规律应用质量分数0.005%阿托品滴眼液1a,与单纯配戴框架镜相比,可以一定程度上延缓儿童近视进展速度,但临床效果不明显。

Anaplasma bovis Infection in Fever and Thrombocytopenia Patients——Anhui Province,China,2021

Summary What is already known about this topic?The genus Anaplasma contains seven recognized bacterial species,mainly transmitted by tick bites.The two species,A.phagocytophilum and A.capra,are known commonly to cause diseases in humans.What is added by this report?Anaplasma bovis was initially thought to be only an animal agent until the first patient case was reported in 2019.This study investigated another two patients who became sick within one month in the same township and were infected with A.bovis in Anhui Province.