To the Editor: The inflammasome, a multiprotein oligomer which regulates the innate immune functions by activating caspase-1 and catalyzing the hydrolysis and secretion of interleukin (IL)- 1β and IL-18, is an imp...To the Editor: The inflammasome, a multiprotein oligomer which regulates the innate immune functions by activating caspase-1 and catalyzing the hydrolysis and secretion of interleukin (IL)- 1β and IL-18, is an important mediator of ventilator-induced lung injury (VILI).展开更多
基金This work was supported by the grants from Shandong Provincial Natural Science Foundation, China (No. ZR2017PH 045), Projects of Medical and Health Technology Development Program in Shandong Province (No. 2017WS208), and Research Support Fund for Yong Teachers of Jining Medical University (No. JY2016KJ039Y).
文摘To the Editor: The inflammasome, a multiprotein oligomer which regulates the innate immune functions by activating caspase-1 and catalyzing the hydrolysis and secretion of interleukin (IL)- 1β and IL-18, is an important mediator of ventilator-induced lung injury (VILI).