Mycoplasma pneumoniae(M.pneumoniae),primarily transmitted through respiratory droplets when infected individuals cough or sneeze,is a common cause of communityacquired pneumonia,especially among school-age children an...Mycoplasma pneumoniae(M.pneumoniae),primarily transmitted through respiratory droplets when infected individuals cough or sneeze,is a common cause of communityacquired pneumonia,especially among school-age children and adolescents.The infection occurs endemically with an epidemic peak every few years.The worldwide incidence confirmed by direct test methods was reported to be 8.61%between 2017 and 2020 across all age groups[1].展开更多
Kawasaki disease(KD)is a disorder of immune responses.The prevalence of KD among 100,000 children aged 0-4 years was 71.9-110.0 in China,170.9-194.9 in Korea,and 18.1-21.3 in the USA[1].The most severe complication of...Kawasaki disease(KD)is a disorder of immune responses.The prevalence of KD among 100,000 children aged 0-4 years was 71.9-110.0 in China,170.9-194.9 in Korea,and 18.1-21.3 in the USA[1].The most severe complication of KD is coronary artery lesions(CALs),including coronary dilatation and coronary aneurysms,which may even lead to myocardial ischemia,myocardial infarction,and sudden death.展开更多
Omicron variant has been the dominant epidemic variant of novel coronavirus in the world since 2021.Studies have shown that the incidence of severe or critical cases with coronavirus disease 2019(COVID-19)is much lowe...Omicron variant has been the dominant epidemic variant of novel coronavirus in the world since 2021.Studies have shown that the incidence of severe or critical cases with coronavirus disease 2019(COVID-19)is much lower than that of the previous novel coronavirus variants[1,2];however,it is still a major challenge to treat critical pediatric patients with COVID-19,especially for those with underlying diseases.展开更多
School closure and stay-at-home,as a part of non-pharmaceutical interventions (NPI),have been implemented in China since February as an effective way to mitigate the spread of the virus during the COVID-19 outbreak.As...School closure and stay-at-home,as a part of non-pharmaceutical interventions (NPI),have been implemented in China since February as an effective way to mitigate the spread of the virus during the COVID-19 outbreak.As concerns rose over the potential impacts of such NPI measures on children's health,such as longer exposure to digital screens,irregular sleep pattern,weight gain,and loss of cardiorespiratory fitness [1],the Chinese Government,experts on public health,educators on school health,and teachers have been making joint and massive efforts to provide distance learning with well-organized online courses to help.展开更多
基金funded by the Science and Technology Commission of Shanghai Municipality(No.21511104502)Shanghai Hospital Development Center(No.SHDC22022221).
文摘Mycoplasma pneumoniae(M.pneumoniae),primarily transmitted through respiratory droplets when infected individuals cough or sneeze,is a common cause of communityacquired pneumonia,especially among school-age children and adolescents.The infection occurs endemically with an epidemic peak every few years.The worldwide incidence confirmed by direct test methods was reported to be 8.61%between 2017 and 2020 across all age groups[1].
基金partially supported by the National Natural Science Foundation of China 81872915(WMW),82073904(WMW),82121005(YDH),81973373(YDH),21704064(ZQT)and 82270313(SSN)National Science&Technology Major Project of China-Key New Drug Creation and Manufacturing Program 2018ZX09735-001(WMW)and 2018ZX09711002-002-005(YDH)+4 种基金National Major Project of China Science and Technology Innovation 2030 for Brain Science and Brain-Inspired Technology 2021ZD0203400(ZQT)the National Key Basic Research Program of China 2018YFA0507000(WMW)Shanghai Municipal Education Commission-Shanghai Top-Level University Capacity Building Program DGF817029-04(WMW)Hainan Provincial Major Science and Technology Project ZDKJ2021028(YDH and ZQT)Shanghai Municipality Science and Technology Development Fund 21JC1401600(YDH).
文摘Kawasaki disease(KD)is a disorder of immune responses.The prevalence of KD among 100,000 children aged 0-4 years was 71.9-110.0 in China,170.9-194.9 in Korea,and 18.1-21.3 in the USA[1].The most severe complication of KD is coronary artery lesions(CALs),including coronary dilatation and coronary aneurysms,which may even lead to myocardial ischemia,myocardial infarction,and sudden death.
基金The National Key Research and Development Program of China(No.2021ZD0113501)The Shanghai Municipal Three-year Action Plan for Strengthening the Construction of The Public Health System(2020-2022-GWV3.2)The Science and Technology Commission of Shanghai Municipality(No.21511104502).
文摘Omicron variant has been the dominant epidemic variant of novel coronavirus in the world since 2021.Studies have shown that the incidence of severe or critical cases with coronavirus disease 2019(COVID-19)is much lower than that of the previous novel coronavirus variants[1,2];however,it is still a major challenge to treat critical pediatric patients with COVID-19,especially for those with underlying diseases.
基金Children's Hospital of Fudan University,Emergency Research Program on COVID-19,EKXGZX004.
文摘School closure and stay-at-home,as a part of non-pharmaceutical interventions (NPI),have been implemented in China since February as an effective way to mitigate the spread of the virus during the COVID-19 outbreak.As concerns rose over the potential impacts of such NPI measures on children's health,such as longer exposure to digital screens,irregular sleep pattern,weight gain,and loss of cardiorespiratory fitness [1],the Chinese Government,experts on public health,educators on school health,and teachers have been making joint and massive efforts to provide distance learning with well-organized online courses to help.