A rapidly growing number of successful genome sequencing projects in plant pathogenic fungi greatly increase the demands for tools and methodologies to study fungal pathogenicity at genomic scale. Magnaporthe oryzae i...A rapidly growing number of successful genome sequencing projects in plant pathogenic fungi greatly increase the demands for tools and methodologies to study fungal pathogenicity at genomic scale. Magnaporthe oryzae is an economically important plant pathogenic fungus whose genome is fully sequenced. Recently we have reported the development and application of functional genomics platform technologies in M. oryzae. This model approach would have many practical ramifications in design and implementation of upcoming functional genomics studies of filamentous fungi aimed at understanding fungal pathogenicity.展开更多
Plants possess effective immune systems that defend against most microbial attackers.Recent plant immunity research has focused on the classic binary defense model involving the pivotal role of small-molecule hormones...Plants possess effective immune systems that defend against most microbial attackers.Recent plant immunity research has focused on the classic binary defense model involving the pivotal role of small-molecule hormones in regulating the plant defense signaling network.Although most of our current understanding comes from studies that relied on information derived from a limited number of pathosystems,newer studies concerning the incredibly diverse interactions between plants and microbes are providing additional insights into other novel mechanisms.Here,we review the roles of both classical and more recently identified components of defense signaling pathways and stress hormones in regulating the ambivalence effect during responses to diverse pathogens.Because of their different lifestyles,effective defense against biotrophic pathogens normally leads to increased susceptibility to necrotrophs,and vice versa.Given these opposing forces,the plant potentially faces a trade-off when it mounts resistance to a specific pathogen,a phenomenon referred to here as the ambivalence effect.We also highlight a novel mechanism by which translational control of the proteins involved in the ambivalence effect can be used to engineer durable and broad-spectrum disease resistance,regardless of the lifestyle of the invading pathogen.展开更多
基金a grant from Biogreen 21 Project (No. 20080401034044)the Rural Development Administration of Korea, the Crop Functional Genomics Center (No. CG1141) of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology of Koreathe Korean Research Foundation Grant (No. KRF-2006-005-J04701)
文摘A rapidly growing number of successful genome sequencing projects in plant pathogenic fungi greatly increase the demands for tools and methodologies to study fungal pathogenicity at genomic scale. Magnaporthe oryzae is an economically important plant pathogenic fungus whose genome is fully sequenced. Recently we have reported the development and application of functional genomics platform technologies in M. oryzae. This model approach would have many practical ramifications in design and implementation of upcoming functional genomics studies of filamentous fungi aimed at understanding fungal pathogenicity.
基金supported by grants from the National Research Foundation of Korea(NRF)(2018R1A5A1023599,2020R1A2B5B03096402,and 2021M3H9A1096935 to Y.-H.L.and 2019R1I1A1A01059802 to C.-Y.K.).C.-Y.K.is grateful for a graduate fellowship from the Brain Korea 21 Plus Program.
文摘Plants possess effective immune systems that defend against most microbial attackers.Recent plant immunity research has focused on the classic binary defense model involving the pivotal role of small-molecule hormones in regulating the plant defense signaling network.Although most of our current understanding comes from studies that relied on information derived from a limited number of pathosystems,newer studies concerning the incredibly diverse interactions between plants and microbes are providing additional insights into other novel mechanisms.Here,we review the roles of both classical and more recently identified components of defense signaling pathways and stress hormones in regulating the ambivalence effect during responses to diverse pathogens.Because of their different lifestyles,effective defense against biotrophic pathogens normally leads to increased susceptibility to necrotrophs,and vice versa.Given these opposing forces,the plant potentially faces a trade-off when it mounts resistance to a specific pathogen,a phenomenon referred to here as the ambivalence effect.We also highlight a novel mechanism by which translational control of the proteins involved in the ambivalence effect can be used to engineer durable and broad-spectrum disease resistance,regardless of the lifestyle of the invading pathogen.
