Objective To investigate the effects of alcohol intake on penile structure and function in rats. Methods Thirty adult male Wistar rats were randomly divided into two groups: control group and alcohol intake group. The...Objective To investigate the effects of alcohol intake on penile structure and function in rats. Methods Thirty adult male Wistar rats were randomly divided into two groups: control group and alcohol intake group. They were administered with 2 mL of normal saline and 40% alcohol solution respectively through gastric tubes every day. Three months later, the animal model of alcohol intake was evaluated by modified Nayagida's method, and the effects of alcohol on the rats were studied by sexual behavior, the number of apomorphine-induced penile erection, level of testosterone in the sera, and the content of penile smooth muscle. Results The scores of animal model of alcohol intake evaluated by Nayagida's method were 0.66±2.05 in the control group and 9.26±5.50 in the alcohol intake group(P<0.05), which indicated that an animal model of alcohol intake was successfully established. Sexual behavior, the number of apomorphine-induced penile erection, testosterone level in the sera, and the content of penile smooth muscle of the alcohol intake group were all statistically different as compared with the control group(P<0.05). Conclusion Alcohol intake induces sexual dysfunction in rats, which may be due to the decline of testosterone level in the sera and decline of penile smooth muscle.展开更多
Aconventional procedure for treating hematospermia is to insert a ureteroscope or seminal vesiculoscope into the prostatic utr/de through the urethra, and then dilate the ejaculatory duct opening using the scope or th...Aconventional procedure for treating hematospermia is to insert a ureteroscope or seminal vesiculoscope into the prostatic utr/de through the urethra, and then dilate the ejaculatory duct opening using the scope or the catheter. However, the ejaculatory duct stenosis may occur after the simple ureteroscopy. We compared the outcomes of treating hematospermia using holmium laser incision through a ureteroscope and using simple ureteroscopy. Retrospective method was used to analyze 67 intractable hematospermia cases. Varying degrees of ejaculatory duct stenosis or obstruction were observed in all the patients. Postoperative follow-up was conducted for 6 months up to 3 years. Two patients who underwent the simple ureteroscopy experienced hematospermia recurrence in 6 and 8 months, respectively. No recurrence was found in all the patients who underwent the holmium laser incision. We have found that the holmium laser incision through a ureteroscope shows a better outcome than the simple ureteroscop~展开更多
文摘Objective To investigate the effects of alcohol intake on penile structure and function in rats. Methods Thirty adult male Wistar rats were randomly divided into two groups: control group and alcohol intake group. They were administered with 2 mL of normal saline and 40% alcohol solution respectively through gastric tubes every day. Three months later, the animal model of alcohol intake was evaluated by modified Nayagida's method, and the effects of alcohol on the rats were studied by sexual behavior, the number of apomorphine-induced penile erection, level of testosterone in the sera, and the content of penile smooth muscle. Results The scores of animal model of alcohol intake evaluated by Nayagida's method were 0.66±2.05 in the control group and 9.26±5.50 in the alcohol intake group(P<0.05), which indicated that an animal model of alcohol intake was successfully established. Sexual behavior, the number of apomorphine-induced penile erection, testosterone level in the sera, and the content of penile smooth muscle of the alcohol intake group were all statistically different as compared with the control group(P<0.05). Conclusion Alcohol intake induces sexual dysfunction in rats, which may be due to the decline of testosterone level in the sera and decline of penile smooth muscle.
文摘Aconventional procedure for treating hematospermia is to insert a ureteroscope or seminal vesiculoscope into the prostatic utr/de through the urethra, and then dilate the ejaculatory duct opening using the scope or the catheter. However, the ejaculatory duct stenosis may occur after the simple ureteroscopy. We compared the outcomes of treating hematospermia using holmium laser incision through a ureteroscope and using simple ureteroscopy. Retrospective method was used to analyze 67 intractable hematospermia cases. Varying degrees of ejaculatory duct stenosis or obstruction were observed in all the patients. Postoperative follow-up was conducted for 6 months up to 3 years. Two patients who underwent the simple ureteroscopy experienced hematospermia recurrence in 6 and 8 months, respectively. No recurrence was found in all the patients who underwent the holmium laser incision. We have found that the holmium laser incision through a ureteroscope shows a better outcome than the simple ureteroscop~