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Gao's double-way approach for laparoscopic D2 radical surgery for gastric cancer 被引量:3
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作者 yong-shun gao Jian-Gang Sun +1 位作者 Jing-Jing Huang Peng Chen 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2016年第6期424-426,共3页
Laparoscopic D2 radical surgery for gastric cancer is minimally invasive but complex.In this path:(1) Repeated operation of lesser curvature side;(2) The gastrohepatic ligament is relatively fixed.Hence,it is not easy... Laparoscopic D2 radical surgery for gastric cancer is minimally invasive but complex.In this path:(1) Repeated operation of lesser curvature side;(2) The gastrohepatic ligament is relatively fixed.Hence,it is not easy to expose the suprapancreatic area;and(3) It is not easy to dissect No.1,12 lymph nodes.This area may not be sufficiently cleaned or surrounding vessels may be injured during a resection.So it is critical to choose position fixing,and a clear,fast and convenient operation path.The author,based on his experience,has established a set of procedural steps called "Gao's double-way",lesser omentum approach and traditional greater omentum approach,which are described in detail in this article.The path of this first approach is described as a "W" type of dissection.The second way is the traditional greater omentum approach,whose path is described as a "M" type of dissection.This will enable laparoscopic surgeons to select a suitable path.This new approach not only simplifies the surgery but also provides more space for the subsequent operation,thereby making the surgery more simple,safe and easy. 展开更多
关键词 LAPAROSCOPIC GASTRIC cancer PATH Surgery Operation
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肿瘤相关因素与胃癌患者术后下肢深静脉血栓形成的关系研究 被引量:9
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作者 郜永顺 韩记 +4 位作者 张云飞 陈鹏 黄晶晶 闫西忠 孙建刚 《中国现代医学杂志》 CAS 北大核心 2021年第11期49-53,共5页
目的探讨肿瘤相关因素与胃癌患者术后下肢深静脉血栓形成之间的关系,为肿瘤患者术后血栓防治提供参考。方法收集2016年10月—2018年12月于郑州大学第一附属医院胃肠外科手术的258例胃癌患者的临床资料,统计手术后患者下肢深静脉血栓形成... 目的探讨肿瘤相关因素与胃癌患者术后下肢深静脉血栓形成之间的关系,为肿瘤患者术后血栓防治提供参考。方法收集2016年10月—2018年12月于郑州大学第一附属医院胃肠外科手术的258例胃癌患者的临床资料,统计手术后患者下肢深静脉血栓形成(DVT)人数,分析肿瘤相关因素对下肢DVT的影响。结果 135例患者中,术后发生下肢DVT 60例(44.4%),其中左下肢19例(14.1%),右下肢11例(8.1%),双侧下肢30例(22.2%)。根据术后下肢DVT情况分为血栓组和非血栓组。两组术前是否行新辅助化疗和手术后CA125水平比较,差异有统计学意义(P <0.05)。多因素Logistic回归分析结果显示手术后CA125水平升高超过5 u/ml[OR=3.227(95%CI:1.181,8.812)]是术后下肢DVT发生的危险因素。新辅助化疗后两组缓解率比较,差异有统计学意义(P=0.018),非血栓组缓解率更高。结论术后CA125水平较术前升高超过5 u/ml的患者术后发生下肢DVT的人数明显增加;新辅助化疗后病情缓解的患者术后发生血栓的风险降低。 展开更多
关键词 胃肿瘤 静脉血栓形成 围手术期
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血清肿瘤标志物检测在不同分化程度进展期胃癌中的表达差异及对肿瘤复发的监测意义 被引量:8
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作者 郜永顺 王依明 +7 位作者 黄晶晶 张云飞 陈鹏 闫西忠 孙建刚 樊晓金 韩记 陈锃烺 《世界华人消化杂志》 CAS 2019年第6期361-366,共6页
背景癌胚抗原(carcinogenic antigen, CEA)、癌相关糖类抗原(carbohydrate antigen, CA)19-9及CA72-4三种血清肿瘤标志物作为辅助胃癌诊断及评估预后的指标被临床医生广泛应用,但此三种血清肿瘤标志物在不同分化程度的进展期胃癌中的临... 背景癌胚抗原(carcinogenic antigen, CEA)、癌相关糖类抗原(carbohydrate antigen, CA)19-9及CA72-4三种血清肿瘤标志物作为辅助胃癌诊断及评估预后的指标被临床医生广泛应用,但此三种血清肿瘤标志物在不同分化程度的进展期胃癌中的临床意义是否相同还是目前临床研究中的争议点,其应用缺乏科学性,并且能否真实客观的对不同分化程度的胃癌患者做出病情评估仍缺乏有力的循证医学证据和深入研究.目的分析CEA、CA19-9及CA72-4等三种血清肿瘤标志物在不同分化程度进展期胃癌患者血清中的表达差异.方法回顾性分析2013-01/2017-10间在郑州大学第一附属医院就诊的111例胃癌患者临床病例参数、初诊及肿瘤复发后血清肿瘤标志物以及预后资料.结果初诊时CEA、CA19-9及CA72-4等三种血清肿瘤标志物的阳性率表现中分化组高于低分化组与印戒细胞癌、黏液腺癌组(χ~2=6.821, P=0.033;χ~2=10.748, P=0.005;χ~2=9.188, P=0.010).肿瘤复发后三种肿瘤标志物的阳性率表现出与初诊时相同的的趋势,即中分化组高于低分化组与印戒细胞癌、黏液腺癌组(χ~2=7.334, P=0.026;χ~2=10.700, P=0.005;χ~2=9.303,P=0.010).三种血清肿瘤标志物初诊时为阴性而肿瘤复发后转为阳性的概率(转阳率)也表现出与初诊及肿瘤复发后相同的结果(χ~2=8.673, P=0.013;χ~2=9.065, P=0.011;χ~2=8.563, P=0.014).术后首次检验值较肿瘤复发后的差值在CEA、CA19-9及CA72-4中均表现为在分化差(中分化、印戒细胞癌及黏液腺癌)的肿瘤中数值更高(F=4.175, P=0.022; F=4.167,P=0.022; F=5.801, P=0.006).结论分化程度越差的胃癌其血清CEA、CA19-9及CA72-4表达越弱,但出现肿瘤标志物阳性时的检验数值较高,此三种肿瘤标志物对于差分化胃癌患者的辅助诊断和评估肿瘤复发较中分化腺癌临床价值低. 展开更多
关键词 胃肿瘤 血清肿瘤标志物 分化程度
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原发性小肠肿瘤临床症状与病理类型相关性分析 被引量:2
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作者 郜永顺 樊晓金 +5 位作者 黄晶晶 张云飞 陈鹏 闫西忠 孙建刚 王依明 《世界华人消化杂志》 CAS 2018年第20期1253-1258,共6页
目的提高原发性小肠肿瘤病理类型的初步及术前诊断率.方法回顾性分析郑州大学第一附属医院2011-08/2017-02所有经手术治疗及病理证实的197例原发性小肠肿瘤的临床症状与病理类型特征.结果原发性小肠肿瘤不同的病理类型最常见临床症状不... 目的提高原发性小肠肿瘤病理类型的初步及术前诊断率.方法回顾性分析郑州大学第一附属医院2011-08/2017-02所有经手术治疗及病理证实的197例原发性小肠肿瘤的临床症状与病理类型特征.结果原发性小肠肿瘤不同的病理类型最常见临床症状不同.腹部包块是高危险度间质瘤患者(38/63)最常见症状,消化道出血是低中危险度间质瘤患者(35/60)最常见症状,腹痛是恶性淋巴瘤(25/32)、息肉(6/6)患者最常见症状,腹胀(3/5)是腺癌患者最常见症状.原发性小肠肿瘤初步确诊率为11.2%(22/197),其中90.91%(20/22)的患者为CT检查所明确.结论原发性小肠肿瘤不同病理类型最常见症状不同,结合不同病理类型肿瘤影像学表现特点,合理选择检查方式,可提高肿瘤病理类型初步及术前诊断率,合理选择治疗方案,提高患者生存率. 展开更多
关键词 小肠 肿瘤 病理 诊断
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Sternal Reconstruction of Deep Sternal Wound Infections Following Median Sternotomy by Single-stage Muscle Flaps Transposition 被引量:1
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作者 Song Wu Feng Wan +4 位作者 yong-shun gao Zhe Zhang Hong Zhao Zhong-qi Cui Ji-yan Xie 《Chinese Medical Sciences Journal》 CAS CSCD 2014年第4期208-213,共6页
Objective To assess clinical effectiveness of using bilateral pectoralis major or plus rectus abdominis muscle flaps in treating deep sternal wound infection(DSWI) following median sternotomy. Methods Between January ... Objective To assess clinical effectiveness of using bilateral pectoralis major or plus rectus abdominis muscle flaps in treating deep sternal wound infection(DSWI) following median sternotomy. Methods Between January 2009 and December 2013, 19 patients with DSWI after median sternotomy for cardiac surgery were admitted to our hospital, including 14 males(73.7%) and 5 females(26.3%), aged 55±13(18-78) years. According to the Pairolero classification of infected median sternotomies, 3(15.8%) patients were type II, and the other 16(84.2%) were type III. Surgical procedure consisted of adequate debridement of infected sternum, costal cartilage, granulation, steel wires, suture residues and other foreign substances. Sternal reconstruction used the bilateral pectoralis major or plus rectus abdominis muscle flaps to obliterate dead space. The drainage tubes were placed and connected to a negative pressure generator for adequate drainage. Results There were no intraoperative deaths. In 15 patients(78.9%), bilateral pectoral muscle flaps were mobilized sufficiently to cover and stabilize the defect created by wound debridement. 4 patients(21.0%) needed bilateral pectoral muscle flaps plus rectus abdominis muscle flaps because their pectoralis major muscle flaps could not reach the lowest portion of the wound. 2 patients(10.5%) presented with subcutaneous infection, and 3 patients(15.8%) had hematoma. They recovered following local debridement and medication. 17 patients(89.5%) were examined at follow-up 12 months later, all healed and having stable sternum. No patients showed infection recurrence during the follow-up period over 12 months. Conclusion DSWI following median sternotomy may be effectively managed with adequate debridement of infected tissues and reconstruction with bilateral pectoralis major muscle or plus rectus abdominis muscle flap transposition. 展开更多
关键词 median STERNOTOMY deep sternal wound infections sternal OSTEOMYELITIS sing-stage pectoralis major MUSCLE FLAP RECTUS abdominis MUSCLE FLAP
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