Numerical and Experimental Evaluation of Shine-Through Loss and Beam Heating Due to Neutral Beam Injection on EAST

This research applies experimental measurements and NUBEAM,ONETWO and TRANSP modules to investigate the shine-through(ST)loss ratio and beam heating percentage of neutral beam injection on EAST.Measurements and simulations confirm that the ST loss ratio increases linearly with beam energy,and decreases exponentially with plasma density.Moreover,using the multi-step fitting method,we present analytical quantitative expressions of ST loss ratio and beam heating percentage,which are valuable for the high parameter long-pulse experiments of EAST.

Misdiagnosed Angioimmunoblastic T-cell Lymphoma Secondary to Cranial Astrocytoma

A case of angioimmunoblastic T-cell lymphoma （AITL） which was misdiagnosed as adult Still＇s disease was presented. The clinical and laboratory characteristics of this case and related literatures were analyzed and reviewed. The patient was finally diagnosed as AITL （Ann Arbor classification： Stage IIIB） secondary to cranial astrocytoma （WHO classification： Stage III）, complicated with severe pulmonary infection because of long time treatment of corticosteroid and misdiagnosis （about one and a half year）. It is concluded that AITL is a rare disease which was easily misdiagnosed. The diagnosis of AITL should combine the clinical manifestation with pathological biopsy as well as corresponding immunohistochemical tests.

Effects of <i>Baicalin</i>and <i>Ligustrazine</i>on airway inflammation and remodeling and underlying mechanism in asthmatic rats

Aim: To explore the effects of Baicalin and Ligustrazine on airway inflammation and construction and underlying mechanisms through the expressions of GATA-3, IL-5, MMP-9 and TIMP-1 in asthmatic rats. Methods: 30 Wistar rats were randomly divided equally into five groups. Lung tissues were sliced. WBC and Eos in lung tissue were estimated by HE stain and the expressions of IL-5, GATA-3, MMP-9, TIMP-1 and collagen type IV in lung tissue were observed by immunohistochemistry. The airway wall and airway smooth muscle thicknesses were measured by computed image analysis system. Results: Compared with asthma group, EOS counts and the expression of IL-5 and GATA-3 in the lung tissue were significantly lower in normal controlled groups (P Baicalin or Ligustrazine, EOS decreased, and the thicknesses of airway wall and airway smooth muscle became thinner compared with asthma group. Meanwhile, the expression of collagen type IV, IL-5, GATA-3, MMP-9 and TIMP-1 significantly decreased (P < 0.05). Airway wall thickness and collagen type Ⅳ were associated with Eos, IL-5, TAGA-3, MMP-9, TIMP-1 and MMP-9/ TIMP-1. Conclusion: Two herbs could diminish infiltration of EOS with inhibiting the expressions of IL-5, and GATA-3, meanwhile, decrease the deposition of collagen type IV and the thickness of the airway smooth muscle through regulating MMP-9, TIMP-1 level and the balance between MMP-9 and TIMP-1, additionally, had synergetic effects.

Effects of Soothing Liver and Invigorating Spleen Recipe on Lipid Metabolism Disorders in Kupffer Cells of NAFLD Rats by LXRα/SREBP-1c Signal Pathway

Objective To investigate the mechanism of lipid metabolism disorders in Kupffer cells （KCs） of non-alcoholic fatty liver disease （NAFLD） rats mediated by LXRα-SREBP-lc pathway and the interference of soothing liver and invigorating spleen recipe （SLISR） on it. Methods SD male rats were randomly divided into five groups： normal, model, soothing liver recipe （SLR）, invigorating spleen recipe （ISR）, and soothing liver and invigorating spleen recipe （SLISR） groups. The rats in treatment groups were administered for 8 weeks. The liver tissue was stained with H＆E and oil red O. The levels of hepatic lipid and blood lipid were measured by biochemical analyzer. KCs were isolated from the livers of rats to evaluate the expression of LXRα, SREBP-1 C, and FAS mRNA by real-time fluorescence quantitative PCR tests; LXRα, SREBP-1C, and FAS proteins were measured by Western blotting. Results The H＆E and oil red O staining results showed that the model rats successfully reproduced typical pathogenetic and histopathological features of NAFLD. The levels of hepatic lipid and blood lipid in the model rats were dramatically increased. Compared with the model group, the values of hepatic lipid and blood lipid in the treatment groups were significantly ameliorated （P〈 0.05, 0.01 ）. The yields of purified KCs from each rat were 2×10^7-3×10^7. The viability of KCs was higher than 95%, with the purity over 90.18%. Compared with the model group, the expression of LXRα, SREBP-1C, and FAS mRNA and proteins was decreased in all treatment groups, especially in the SLR group （P〈 0.05）. Conclusion SLISR may protect liver against injury included by lipid metabolism disorders in KCs through LXRα/ SREBP-1 c signaling pathway, which may be an important mechanism for the prevention and treatment of NAFLD.

A Quantum Secret Sharing Scheme Using Orbital Angular Momentum onto Multiple Spin States Based on Fibonacci Compression Encoding

Since the use of a quantum channel is very expensive for transmitting large messages, it is vital to develop an effective quantum compression encoding scheme that is easy to implement. Given that, with the single-photon spin-orbit entanglement, we propose a quantum secret sharing scheme using orbital angular momentum onto multiple spin states based on Fibonacci compression encoding. In our proposed scheme, we can represent the frequency of any secret message which is typically collection of bits encodings of text or integers as a bitstring using the base Fibonacci sequence, which is encoded multiple spin states for secret shares transmitted to participants. We demonstrate that Fibonacci compression encoding carries excellent properties that enable us to achieve more robust quantum secret sharing schemes with fewer number of photons.