Human nervous system,which is composed of neuron and synapse networks,is capable of processing information in a plastic,dataparallel,fault-tolerant,and energy-efficient approach.Inspired by the ingenious working mecha...Human nervous system,which is composed of neuron and synapse networks,is capable of processing information in a plastic,dataparallel,fault-tolerant,and energy-efficient approach.Inspired by the ingenious working mechanism of this miraculous biological data processing system,scientists have been devoting great efforts to ar-tificial neural systems based on synaptic devices in recent decades.The continuous development of bioinspired sensors and synaptic devices in recent years have made it possible that artificial sensory neural systems are capable of capturing and processing stimuli informa-tion in real time.The progress of biomimetic sensory neural systems could provide new methods for next-generation humanoid robotics,human-machine interfaces,and other frontier applications.Herein,this review summarized the recent progress of synaptic devices and biomimetic sensory neural systems.Additionally,the opportunities and remaining challenges in the further development of biomimetic sensory neural systems were also outlined.展开更多
Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously.For example,peripheral arterial disease(PA...Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously.For example,peripheral arterial disease(PAD)is the third most prevalent cardiovascular disease,but the means of diagnosing and monitoring this disease are limited because the affected area is usually in the non‐pulsatile area away from the heart.Herein,we report on an ultrathin and ultralight multi‐vital near‐infrared optoelectronic biosensor for the diagnosis and rehabilitation monitoring of regional tissue hemodynamics,which is suitable for mounting on the skin for long‐term measurement.The device can simultaneously detect tissue oxygen saturation,heart rate,arterial blood oxygen,and tissue perfusion and shows potential for various hypoxia monitoring applications.Moreover,the tissue hemodynamics detected by this device showed a highly accordance with the ankle‐brachial index and CT angiography obtained by traditional clinical methods.Therefore,our design was able to accurately diagnose and effectively evaluate PAD patients before and after surgery.The on‐skin optoelectronic biosensor shows potential in biological oxygen‐mediated behavior evaluation,injury‐state monitoring,PAD clinical diagnosis optimization,and after surgery care.展开更多
基金This work was supported by the National Key Research and Development Program of China(2021YFA1401103)the National Natu-ral Science Foundation of China(61825403,61921005,and 61674078)the Priority Academic Program Development of Jiangsu Higher Education Insti-tutions.The Postgraduate Research&Innovation Program of Jiangsu Province(KYCX21_0049 to J.-H.Z.).
文摘Human nervous system,which is composed of neuron and synapse networks,is capable of processing information in a plastic,dataparallel,fault-tolerant,and energy-efficient approach.Inspired by the ingenious working mechanism of this miraculous biological data processing system,scientists have been devoting great efforts to ar-tificial neural systems based on synaptic devices in recent decades.The continuous development of bioinspired sensors and synaptic devices in recent years have made it possible that artificial sensory neural systems are capable of capturing and processing stimuli informa-tion in real time.The progress of biomimetic sensory neural systems could provide new methods for next-generation humanoid robotics,human-machine interfaces,and other frontier applications.Herein,this review summarized the recent progress of synaptic devices and biomimetic sensory neural systems.Additionally,the opportunities and remaining challenges in the further development of biomimetic sensory neural systems were also outlined.
基金The National Key Research and Development program,Grant/Award Number:2021YFA1401103China National Funds for Distinguished Young Scientists,Grant/Award Number:61825403The National Natural Science Foundation of China,Grant/Award Numbers:61921005,61674078。
文摘Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously.For example,peripheral arterial disease(PAD)is the third most prevalent cardiovascular disease,but the means of diagnosing and monitoring this disease are limited because the affected area is usually in the non‐pulsatile area away from the heart.Herein,we report on an ultrathin and ultralight multi‐vital near‐infrared optoelectronic biosensor for the diagnosis and rehabilitation monitoring of regional tissue hemodynamics,which is suitable for mounting on the skin for long‐term measurement.The device can simultaneously detect tissue oxygen saturation,heart rate,arterial blood oxygen,and tissue perfusion and shows potential for various hypoxia monitoring applications.Moreover,the tissue hemodynamics detected by this device showed a highly accordance with the ankle‐brachial index and CT angiography obtained by traditional clinical methods.Therefore,our design was able to accurately diagnose and effectively evaluate PAD patients before and after surgery.The on‐skin optoelectronic biosensor shows potential in biological oxygen‐mediated behavior evaluation,injury‐state monitoring,PAD clinical diagnosis optimization,and after surgery care.
