Dear Editor, Multiple myeloma (MM) is a disease characterized by the clonal expansion of malignant plasma cells in the marrow, leading to anemia, hypercalcemia, bone lesion, and renal dysfunction [1]. Immunoglobulin D...Dear Editor, Multiple myeloma (MM) is a disease characterized by the clonal expansion of malignant plasma cells in the marrow, leading to anemia, hypercalcemia, bone lesion, and renal dysfunction [1]. Immunoglobulin D (IgD) myeloma is a rare subtype of MM, accounting for approximately 1% to 2% of all MM patients [2]. It occurs at a young age, often accom-panied with a high disease burden and short median sur-vival (18-21 months) [3, 4]. Several studies have suggested that in patients with IgD subtype, the outcomes of those who have had undergone autologous stem cell transplanta-tion (ASCT) were superior than those treated with chemo-therapy alone [5, 6]. However, these have been debatable as other reports have displayed opposite results [7, 8].展开更多
Surface lattice resonances(SLRs)with ultra-narrow linewidth(high quality factor)can enhance light–matter interactions at the nanoscale and modulate the propagating light from the emission wavelength direction to effi...Surface lattice resonances(SLRs)with ultra-narrow linewidth(high quality factor)can enhance light–matter interactions at the nanoscale and modulate the propagating light from the emission wavelength direction to efficiency by photonic band engineering.Therefore,SLRs can serve as an excited candidate to enhance and,more importantly,modulate amplified spontaneous emission(ASE)with more optical parameters.Here,this work presents a system of two-dimensional Ag-coated Al nanocone array(Ag-NCA)packaged with Nile red,and a normal ASE with 15-fold enhancement is observed under external driving light.This enhancement fades away,obviously,in the case of the off-normal condition,as the optical feedback evolves from the band edge steady state to the propagating state.The ASE of this hybrid plasmonic system expands the possibilities of interaction between light and matter and has great promise for applications in nanolasing,super-resolution imaging,and photonic integration circuits.展开更多
文摘Dear Editor, Multiple myeloma (MM) is a disease characterized by the clonal expansion of malignant plasma cells in the marrow, leading to anemia, hypercalcemia, bone lesion, and renal dysfunction [1]. Immunoglobulin D (IgD) myeloma is a rare subtype of MM, accounting for approximately 1% to 2% of all MM patients [2]. It occurs at a young age, often accom-panied with a high disease burden and short median sur-vival (18-21 months) [3, 4]. Several studies have suggested that in patients with IgD subtype, the outcomes of those who have had undergone autologous stem cell transplanta-tion (ASCT) were superior than those treated with chemo-therapy alone [5, 6]. However, these have been debatable as other reports have displayed opposite results [7, 8].
基金National Defense Science and Technology Innovation Fund of the Chinese Academy of Sciences(22-ZZCX-064)National Natural Science Foundation of China(61905051)Natural Science Foundation of Heilongjiang Province(LH2020F027)。
文摘Surface lattice resonances(SLRs)with ultra-narrow linewidth(high quality factor)can enhance light–matter interactions at the nanoscale and modulate the propagating light from the emission wavelength direction to efficiency by photonic band engineering.Therefore,SLRs can serve as an excited candidate to enhance and,more importantly,modulate amplified spontaneous emission(ASE)with more optical parameters.Here,this work presents a system of two-dimensional Ag-coated Al nanocone array(Ag-NCA)packaged with Nile red,and a normal ASE with 15-fold enhancement is observed under external driving light.This enhancement fades away,obviously,in the case of the off-normal condition,as the optical feedback evolves from the band edge steady state to the propagating state.The ASE of this hybrid plasmonic system expands the possibilities of interaction between light and matter and has great promise for applications in nanolasing,super-resolution imaging,and photonic integration circuits.
