AIM: To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As<sub>2</sub>O<sub>3</sub>); and to stu...AIM: To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As<sub>2</sub>O<sub>3</sub>); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2.展开更多
To the Editor： Painless intubation is extremely important to avoid perforation during colonoscopy. Ultrathin colonoscopes and standard gastroscopes （9.2-9.8 mm） can increase the proportion of patients with painless...To the Editor： Painless intubation is extremely important to avoid perforation during colonoscopy. Ultrathin colonoscopes and standard gastroscopes （9.2-9.8 mm） can increase the proportion of patients with painless intubation, but there remain approximately 10% patients who surlier fiom moderate or severe abdominal pain. Sedation and anesthesia during colonoscopy could alleviate patient＇s suffering and improve the success rate of colonoscopy, but warning effect of abdominal pain disappears and the risk of perforation is increasing.In this paper, a transnasal gastroscope （5.9 ram） was used to simulate the ultrathin colonoscope for examination. The authors hypothesized that none of the patients would have severe abdominal pain in this study, demonstrating good safety of transnasal gastroscope on colon examination.展开更多
基金Supported by The Heilongjiang Provincial Natural Science Foundation of China,No.D2006-51
文摘AIM: To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As<sub>2</sub>O<sub>3</sub>); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2.
文摘To the Editor： Painless intubation is extremely important to avoid perforation during colonoscopy. Ultrathin colonoscopes and standard gastroscopes （9.2-9.8 mm） can increase the proportion of patients with painless intubation, but there remain approximately 10% patients who surlier fiom moderate or severe abdominal pain. Sedation and anesthesia during colonoscopy could alleviate patient＇s suffering and improve the success rate of colonoscopy, but warning effect of abdominal pain disappears and the risk of perforation is increasing.In this paper, a transnasal gastroscope （5.9 ram） was used to simulate the ultrathin colonoscope for examination. The authors hypothesized that none of the patients would have severe abdominal pain in this study, demonstrating good safety of transnasal gastroscope on colon examination.
