Clinical effect of sodium hyaluronate joint cavity filling combined with exercise therapy on patients with post-traumatic knee arthritis

Objective:To research the sodium hyaluronate joint cavity filling combined with exercise therapy on the indicator of pain,motor function,and levels of inflammatory factors in joint fluid in patients with post-traumatic knee arthritis.Method Totally 100 patients(Department of Orthopaedics,The second Affiliated Hospital to Liaoning University of Chinese Medicine,2013.10-2018.8)with post-traumatic knee arthritis were selected,then they were divided into observation group(n=50)and control group(n=50).The control group was given glucosamine sulfate and sodium hyaluronate joint cavity filling,the observation group was given leg press with visual feedback,they were treated 4 weeks.Assessing the pain degree through visual analog scale(VAS),hospital for special surgery knee score(HSS)as the indicator of motor function,inflammatory factor(TNF-α,IL-6,and IL-8)in the joint fluid.Results The score of VAS were lower than pretherapy(P<0.05),the degree of VAS of observation group were lower than control group(P<0.05).The score of HSS were higher than pretherapy(P<0.05),the degree of VAS of observation group were higher than control group(P<0.05).The inflammatory factor(TNF-α,IL-6,and CRP)in the joint fluid were lower than pretherapy(P<0.05),and the observation group were lower than control group(P<0.05).Conclusions Giving sodium hyaluronate joint cavity filling combined with exercise therapy can improve the function of joint.

Clinical effect of four-dimensional therapy on patients with cervical hypertension

Objective:To research the effect of four-dimensional therapy on the clinical effect (symptoms, blood pressure, and pain degree), the changes of blood rheology and arterial (left vertebral artery (LVA), right vertebral artery (RVA), and basal artery (BA)) hemodynamics (average cerebral blood flow (Vm), resistance index (RI), pulsatility index (PI)) on patients with cervical hypertension. Method: Selecting 120 patients (Department of Orthopaedics, the second Affiliated Hospital to Liaoning University of Chinese Medicine, 2012.6-2018.10) with cervical hypertension, then they were divided into observation group (n=60) and control group (n=60). The control group were given enalapril meleate (amlodipine besylate) +conventional therapy (acupuncture treatment and massage), the observation group were given four-dimensional therapy on the basic of control group, they were treated 3 weeks. The primary endpoints were the changes from baseline to week 3 in the symptoms and function were scored using the Evaluation Scale for Cervical Vertigo, the secondary endpoints were changes from baseline to month 3 in the artery hemodynamics (Vm, RI, and PI) in the BA, LVA, blood rheology, and RVA. At last, assessing the pain degree through visual analog scale (VAS), measuring the blood pressure, and accessing the clinical effect.Results:The score of vertigo in the two groups had no statistical significance before treatment, the score of vertigo in the two groups were higher than pretherapy, and had statistical significance, and the score in the observation group were higher than control group, and had statistical significance. The hemodynamics (Vm, RI, and PI) in the artery (BA, LVA, and RVA) had no statistical significance in the two groups before treatment, and the hemodynamics (Vm) in the artery (BA, LVA, and RVA) were higher than pretherapy, and had statistical significance, the hemodynamics (Vm) in the artery (BA, LVA, and RVA) of observation group were higher than control group, and had statistical significance. The hemodynamics (RI and PI) in the artery (BA, LVA, and RVA) were lower than pretherapy, and had statistical significance, the the hemodynamics (Vm) in the artery (BA, LVA, and RVA) of observation group were lower than control group, and had statistical significance. The blood rheology had no statistical significance in the two groups before treatment, the blood rheology were lower than pretherapy, and had statistical significance, the blood rheology of observation group were lower than control group, and had statistical significance. The degree of VAS had no statistical significance in the two groups before treatment, the degree of VAS was lower than pretherapy, and had statistical significance, the degree of VAS of observation group were lower than control group, and had statistical significance. The blood pressure (systolic pressure and diastolic pressure) had no statistical significance in the two groups before treatment, the blood pressure (systolic pressure and diastolic pressure) were lower than pretherapy, and had statistical significance, the blood pressure (systolic pressure and diastolic pressure) of observation group were lower than control group, and had statistical significance, the clinical effect in the observation group were higher than control group, and had statistical significance.Conclusions:Giving four-dimensional therapy can improve the blood pressure and relieve the pain through improving blood rheology and hemodynamics in the artery in the patients with cervical hypertension.