Incremental age-related one-year MACCE after acute myocardial infarction in the drug-eluting stent era （from KAMIR-NIH registry）

ObjectivesTo 评估年龄相关的一个年专业在在尖锐心肌的梗塞(AMI ) 的经皮的冠的干预(一种总线标准) 以后的不利 cardiocerebrovascular 事件(MACCE ) 。我们从在 2011 年 11 月之间的健康(KAMIR-NIH ) 的朝鲜尖锐心肌的梗塞登记公民 Institue 在 13,104 个 AMI 病人全部的 AMI.MethodsA 以后分析了在年龄和一个年 MACCE 之间的协会， 2015 年 12 月根据年龄被分类进四个组(组我， < 60 年， n = 4199；组 II， 60-70 年， n = 2577；组织 III；70-80 年， n = 2774；组 IV， 80 年， n = 1018 ) 。病人们为 MACCE 合成的一个年被分析(心脏的死亡，心肌的梗塞，目标容器 revascularization，脑血管的事件) 在 AMI.ResultsThe 一个年以后，在 AMI 的 MACCE 是 3.5%( 组我) ， 6.3%( 组 II ) ， 9.6%( 组 III ) 并且 17.6%( 组 IV ) 。在为使参数惊讶的调整以后，分析结果证明有 AMI 的病人有一个年 MACCE 的增长风险[组 II，调整危险比率(aHR )= 1.224， 95% CI：0.965-1.525， P = 0.096；组 III， aHR = 1.316， 95% CI：1.037-1.671， P = 0.024；组 IV， aHR = 1.975， 95% CI：1.500-62.601， P < 0.001 ) 与相比组我。特别，心脏的死亡在玩的主要结束点合成在这效果的一个主要角色(组 II， aHR = 1.335， 95% CI：0.941-1.895， P = 0.106；组 III， aHR = 1.575， 95% CI：1.122-2.210， P = 0.009；组 IV， aHR = 2.803， 95% CI：1.937-4.054， P < 0.001 ).ConclusionsDespite 在 AMI 为一种总线标准推进了技术和药，年龄仍然在临床的结果施加强大的影响。小心的途径，甚至在发达心病学的现代时代被需要为在 AMI 干预年老人口。

Gender differences in clinical outcomes of acute myocardial infarction undergoing percutaneous coronary intervention: insights from the KAMIR-NIH Registry

Background There are numerous but conflicting data regarding gender differences in outcomes following percutaneous coronary intervention(PCI). Furthermore, gender differences in clinical outcomes with acute myocardial infarction(AMI) following PCI in Asian population remain uncertain because of the under-representation of Asian in previous trials. Methods A total of 13,104 AMI patients from Korea Acute Myocardial Infarction Registry-National Institute of Health(KAMIR-NIH) between November 2011 and December 2015 were classified into male(n = 8021, 75.9%) and female(n = 2547, 24.1%). We compared the demographic, clinical and angiographic characteristics, 30-days and 1-year major adverse cardiac and cerebrovascular events(MACCE) in women with those in men after AMI by using propensity score(PS) matching. Results Compared with men, women were older, had more comorbidities and more often presented with non-ST segment elevation myocardial infarction(NSTEMI) and reduced left ventricular systolic function. Over the median follow-up of 363 days, gender differences in both 30-days and 1-year MACCE as well as thrombolysis in myocardial infarction minor bleeding risk were not observed in the PS matched population(30-days MACCE: 5.3% vs. 4.7%, log-rank P = 0.494, HR = 1.126, 95% CI: 0.800-1.585;1-year MACCE: 9.3% vs. 9.0%, log-rank P = 0.803, HR = 1.032, 95% CI: 0.802-1.328;TIMI minor bleeding: 4.9% vs. 3.9%, log-rank P = 0.215, HR = 1.255, 95% CI: 0.869-1.814). Conclusions Among Korean AMI population undergoing contemporary PCI, women, as compared with men, had different clinical and angiographic characteristics but showed similar 30-days and 1-year clinical outcomes. The risk of bleeding after PCI was comparable between men and women during one-year follow up.

Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases

为圣片断举起的完全的 revascularization 的 BackgroundThe 临床的意义心肌的梗塞(STEMI )病人没有心脏性的吃惊，仍然在承认期间是从有 multivessel 疾病的朝鲜心肌的梗塞登记的 1406 个 STEMI 病人全部的 debatable.MethodsA 经历了主要经皮的冠的干预( PPCI )的人，被分析。我们使用了匹配的倾向分数(PSM ) 控制在犯人之间的基线特征的差别仅仅干预(CP ) 和 multivessel 经皮的冠的干预(MP ) ，并且在两倍容器疾病(DVD ) 和三倍的容器疾病(TVD ) 之间。在 discharge.ResultsTVD 病人显示出向的更高的发生以后，主要不利心脏的事件(向)被分析一年(14.2%对8.6%， P = 0.01 )， revascularization 的任何原因(10.6%对5.9%， P = 0.01 )，并且重复一种总线标准(9.5%对5.7%， P = 0.02 )，作为与 DVD 病人相比在一年在以后期间排出。 MP 有效地减少了向(7.3%对13.8%， P = 0.03 )与为死亡的一年，而是所有原因的 CP 相比(1.6%对3.2%， P = 0.38 )， MI (0.4%对0.8%， P = 1.00 )，并且 revascularization 的任何原因(5.3%对9.7%， P = 0.09 )在有 TVD 的病人更高显示出的二治疗 groups.ConclusionsSTEMI 是可比较的向的率，同样与 DVD 相比。MP 表现在 PPCI 期间或在为没有心脏性的吃惊的 STEMI 病人的承认期间特定在这个大放大数据库的向的显示出的更低的率。因此，没有心脏性的吃惊， MP 能为 STEMI 病人被看作一种有效治疗选择。