A case of postoperative spontaneous intussusception after laparoscopic low anterior resection for rectal cancer

Background:Intussusception refers to a condition in which a segment of the intestine invaginates into the lumen of an adjacent segment of the intestine.Postoperative intussusception after gastrointestinal surgery is an uncommon clinical condition,and there is only one case report of small bowel intussusception after rectal cancer surgery.Here,we report a case of spontaneous small bowel intussusception following laparoscopic total mesorectal excision for rectal cancer.Case presentation:A 56-year-old female military officer was referred to the Colorectal Surgical Department for midrectal cancer,8cm from the anal verge.The patient underwent laparoscopic low anterior resection and diverting loop ileostomy.On postoperative day 3,the patient complained of vomiting and abdominal pain,and a follow-up abdomino-pelvic computed tomography scan showed an ileo-ileal type intussusception.After two days of surgical observation,the clinical symptoms were not resolved.The patient underwent exploratory laparotomy.On exploration,intussusception was found 40 cm proximal to the loop ileostomy site.Segmental resection of the ileum was carried out,and there was no pathological leading point on the resected ileum.The patient was discharged on postoperative day 14 after the second operation and has remained in good health for two years.Conclusion:We present a case of spontaneous small bowel intussusception after laparoscopic total mesorectal excision for rectal cancer that was treated by surgical resection 5 days after the index surgery.

Plasmonic bacteria on a nanoporous mirror via hydrodynamic trapping for rapid identification of waterborne pathogens

A rapid,precise method for identifying waterborne pathogens is critically needed for effective disinfection and better treatment.However,conventional methods,such as culture-based counting,generally suffer from slow detection times and low sensitivities.Here,we developed a rapid detection method for tracing waterborne pathogens by an innovative optofluidic platform,a plasmonic bacteria on a nanoporous mirror,that allows effective hydrodynamic cell trapping,enrichment of pathogens,and optical signal amplifications.We designed and simulated the integrated optofluidic platform to maximize the enrichment of the bacteria and to align bacteria on the nanopores and plasmonic mirror via hydrodynamic cell trapping.Gold nanoparticles are self-assembled to form antenna arrays on the surface of bacteria,such as Escherichia coli and Pseudomonas aeruginosa,by replacing citrate with hydroxylamine hydrochloride in order to amplify the signal of the plasmonic optical array.Owing to the synergistic contributions of focused light via the nanopore geometry,self-assembled nanoplasmonic optical antennas on the surface of bacteria,and plasmonic mirror,we obtain a sensitivity of detecting E.coli as low as 102 cells/ml via surface-enhanced Raman spectroscopy.We believe that our label-free strategy via an integrated optofluidic platform will pave the way for the rapid,precise identification of various pathogens.