Dear Editor,Treating psoriatic arthritis(PsA)is always difficult.Systemic treatments can be administered either orally or through intramuscular and intra-articular injection,including conventional synthetics,biologics...Dear Editor,Treating psoriatic arthritis(PsA)is always difficult.Systemic treatments can be administered either orally or through intramuscular and intra-articular injection,including conventional synthetics,biologics and targeted synthetic disease-modifying antirheumatic drugs[1].The alternatives,topical external therapies,are not effective on joint lesions due to drug permeability issues.Drugs injected into the articular cavity are also unsuitable for small peripheral joint lesions,the most common manifestations of PsA.The limited treatment options for PsA present a challenge.展开更多
Dear Editor,We reviewed the paper by Liu et al[1],as part of an umbrella review on PM2.5 and the incidence of respiratory outcomes.We determined that the authors did not account for the PM_(2.5) increments based upon ...Dear Editor,We reviewed the paper by Liu et al[1],as part of an umbrella review on PM2.5 and the incidence of respiratory outcomes.We determined that the authors did not account for the PM_(2.5) increments based upon which primary studies reported their results.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.82073439).
文摘Dear Editor,Treating psoriatic arthritis(PsA)is always difficult.Systemic treatments can be administered either orally or through intramuscular and intra-articular injection,including conventional synthetics,biologics and targeted synthetic disease-modifying antirheumatic drugs[1].The alternatives,topical external therapies,are not effective on joint lesions due to drug permeability issues.Drugs injected into the articular cavity are also unsuitable for small peripheral joint lesions,the most common manifestations of PsA.The limited treatment options for PsA present a challenge.
文摘Dear Editor,We reviewed the paper by Liu et al[1],as part of an umbrella review on PM2.5 and the incidence of respiratory outcomes.We determined that the authors did not account for the PM_(2.5) increments based upon which primary studies reported their results.