Unfavorable Outcome of Percutaneous Coronary Intervention for Coronary Heart Disease with Rare Severe Pericoronary Fat Stranding

Background: Pericoronary fat stranding (PCFS) is a novel noninvasive imaging sign of coronary inflammation, and has important implications for cardiovascular risk stratification, and the outcome of percutaneous coronary intervention (PCI) for coronary heart disease patients with pericoronary fat stranding remains unknown. Aim: We report two rare cases of PCI-treated coronary heart disease patients with severe PCFS. Case Presentation: This is the first report of two rare cases of PCI for patients with coronary heart disease surrounded by severe PCFS. We demonstrated that the outcome in these cases is poor, and in-stent restenosis or occlusion occurs rapidly within 2- 6 months following PCI. However, Case 2 underwent coronary artery bypass grafting after the rapid occurrence of in-stent occlusion, and the bypass graft remained intact over the 5 years following coronary artery bypass grafting. Conclusion: Coronary artery bypass grafting rather than PCI may be appropriate for coronary heart disease patients with severe PCFS.