High-fidelity two-qubit gates are essential for the realization of large-scale quantum computation and simulation.Tunable coupler design is used to reduce the problem of parasitic coupling and frequency crowding in ma...High-fidelity two-qubit gates are essential for the realization of large-scale quantum computation and simulation.Tunable coupler design is used to reduce the problem of parasitic coupling and frequency crowding in manyqubit systems and thus thought to be advantageous. Here we design an extensible 5-qubit system in which center transmon qubit can couple to every four near-neighboring qubits via a capacitive tunable coupler and experimentally demonstrate high-fidelity controlled-phase(CZ) gate by manipulating central qubit and one nearneighboring qubit. Speckle purity benchmarking and cross entropy benchmarking are used to assess the purity fidelity and the fidelity of the CZ gate. The average purity fidelity of the CZ gate is 99.69±0.04% and the average fidelity of the CZ gate is 99.65±0.04%, which means that the control error is about 0.04%. Our work is helpful for resolving many challenges in implementation of large-scale quantum systems.展开更多
The development of high-fidelity two-qubit quantum gates is essential for digital quantum computing.Here,we propose and realize an all-microwave parametric controlled-Z(CZ)gates by coupling strength modulation in a su...The development of high-fidelity two-qubit quantum gates is essential for digital quantum computing.Here,we propose and realize an all-microwave parametric controlled-Z(CZ)gates by coupling strength modulation in a superconducting Transmon qubit system with tunable couplers.After optimizing the design of the tunable coupler together with the control pulse numerically,we experimentally realized a 100 ns CZ gate with high fidelity of 99.38%±0.34%and the control error being 0.1%.We note that our CZ gates are not affected by pulse distortion and do not need pulse correction,providing a solution for the real-time pulse generation in a dynamic quantum feedback circuit.With the expectation of utilizing our all-microwave control scheme to reduce the number of control lines through frequency multiplexing in the future,our scheme draws a blueprint for the high-integrable quantum hardware design.展开更多
Liver transplantation(LT)is considered one of the best treatments for patients with end-stage liver diseases.However,some patients with no significant clinical manifestations or abnormal laboratory tests still experie...Liver transplantation(LT)is considered one of the best treatments for patients with end-stage liver diseases.However,some patients with no significant clinical manifestations or abnormal laboratory tests still experience graft fibrosis during postoperative follow-up,which is often recognized by graft histopathology.Graft fibrosis can lead to graft dysfunction,thereby reducing the survival time of the recipient and even requiring retransplantation.Currently,noninvasive methods are widely applied in the assessment of hepatic and allograft fibrosis.Although both noninvasive diagnostic models based on laboratory examination indicators and elastography technology that can quantify liver stiffness have some value in the evaluation of fibrosis,the diagnostic accuracy and characteristics of these various methods vary and cannot replace liver biopsy completely.In recent years,some liver-protective drugs and proprietary Chinese traditional medicines have been proven to delay or reverse chronic liver fibrosis.Nevertheless,their efficacy and safety for LT recipients need to be further verified.This article reviews the diagnosis and treatment of graft fibrosis after LT to provide a reference for improving the overall survival rate of LT recipients.展开更多
To ensure a long-term quantum computational advantage,the quantum hardware should be upgraded to withstand the competition of continuously improved classical algorithms and hardwares.Here,we demonstrate a superconduct...To ensure a long-term quantum computational advantage,the quantum hardware should be upgraded to withstand the competition of continuously improved classical algorithms and hardwares.Here,we demonstrate a superconducting quantum computing systems Zuchongzhi 2.1,which has 66 qubits in a two-dimensional array in a tunable coupler architecture.The readout fidelity of Zuchongzhi 2.1 is considerably improved to an average of 97.74%.The more powerful quantum processor enables us to achieve larger-scale random quantum circuit sampling,with a system scale of up to 60 qubits and 24 cycles,and fidelity of FXEB=(3·66±0·345)×10^(-4).The achieved sampling task is about 6 orders of magnitude more difficult than that of Sycamore[Nature 574,505(2019)]in the classic simulation,and 3 orders of magnitude more difficult than the sampling task on Zuchongzhi 2.0[arXiv:2106.14734(2021)].The time consumption of classically simulating random circuit sampling experiment using state-of-the-art classical algorithm and supercomputer is extended to tens of thousands of years(about 4·8×104years),while Zuchongzhi 2.1 only takes about 4.2 h,thereby significantly enhancing the quantum computational advantage.展开更多
To the Editor,Liver transplantation(LT)is the only curative therapy for patients with end‐stage liver disease.1 Due to the high incidence of metabolic syndrome after LT,nonalcoholic fatty liver disease(NAFLD)has grad...To the Editor,Liver transplantation(LT)is the only curative therapy for patients with end‐stage liver disease.1 Due to the high incidence of metabolic syndrome after LT,nonalcoholic fatty liver disease(NAFLD)has gradually become an essential cause of post‐LT fibrosis.2 Liver fibrosis can progress to liver cirrhosis and carries the risk of developing hepatocellular carcinoma(HCC),which adversely affects long‐term survival after LT.3,4 Early detection and active intervention for liver fibrosis after LT are crucial in LT recipients.Previous studies have confirmed that transient elastography(TE)could accurately detect liver fibrosis in LT recipients by comparing TE with liver biopsy.展开更多
基金the National Key R&D Program of China(Grant No.2017YFA0304300)the Chinese Academy of Sciences+6 种基金Anhui Initiative in Quantum Information TechnologiesTechnology Committee of Shanghai Municipalitythe National Natural Science Foundation of China(Grants Nos.11905217,11774326,and 11905294)the Shanghai Municipal Science and Technology Major Project(Grant No.2019SHZDZX01)the Natural Science Foundation of Shanghai(Grant No.19ZR1462700)the Key-Area Research and Development Program of Guangdong Provice(Grant No.2020B0303030001)the Youth Talent Lifting Project(Grant No.2020-JCJQ-QT-030)。
文摘High-fidelity two-qubit gates are essential for the realization of large-scale quantum computation and simulation.Tunable coupler design is used to reduce the problem of parasitic coupling and frequency crowding in manyqubit systems and thus thought to be advantageous. Here we design an extensible 5-qubit system in which center transmon qubit can couple to every four near-neighboring qubits via a capacitive tunable coupler and experimentally demonstrate high-fidelity controlled-phase(CZ) gate by manipulating central qubit and one nearneighboring qubit. Speckle purity benchmarking and cross entropy benchmarking are used to assess the purity fidelity and the fidelity of the CZ gate. The average purity fidelity of the CZ gate is 99.69±0.04% and the average fidelity of the CZ gate is 99.65±0.04%, which means that the control error is about 0.04%. Our work is helpful for resolving many challenges in implementation of large-scale quantum systems.
基金the USTC Center for Micro-and Nanoscale Research and Fabrication for supporting the sample fabricationQuantum CTek Co.,Ltd.for supporting the fabrication and the maintenance of room-temperature electronics+7 种基金supported by the National Key R&D Program of China(Grant No.2017YFA0304300)the Chinese Academy of Sciencesthe Anhui Initiative in Quantum Information Technologiesthe Technology Committee of Shanghai Municipalitythe National Natural Science Foundation of China(Grants No.11905217 and 11905294)the Natural Science Foundation of Shanghai(Grant No.19ZR1462700)he Key-Area Research and Development Program of Guangdong Province(Grant No.2020B0303030001)the China Postdoctoral Science Foundation。
文摘The development of high-fidelity two-qubit quantum gates is essential for digital quantum computing.Here,we propose and realize an all-microwave parametric controlled-Z(CZ)gates by coupling strength modulation in a superconducting Transmon qubit system with tunable couplers.After optimizing the design of the tunable coupler together with the control pulse numerically,we experimentally realized a 100 ns CZ gate with high fidelity of 99.38%±0.34%and the control error being 0.1%.We note that our CZ gates are not affected by pulse distortion and do not need pulse correction,providing a solution for the real-time pulse generation in a dynamic quantum feedback circuit.With the expectation of utilizing our all-microwave control scheme to reduce the number of control lines through frequency multiplexing in the future,our scheme draws a blueprint for the high-integrable quantum hardware design.
基金supported by Shandong Province Social Science Popularization and Application Research Project(2021-SKZC-18)。
文摘Liver transplantation(LT)is considered one of the best treatments for patients with end-stage liver diseases.However,some patients with no significant clinical manifestations or abnormal laboratory tests still experience graft fibrosis during postoperative follow-up,which is often recognized by graft histopathology.Graft fibrosis can lead to graft dysfunction,thereby reducing the survival time of the recipient and even requiring retransplantation.Currently,noninvasive methods are widely applied in the assessment of hepatic and allograft fibrosis.Although both noninvasive diagnostic models based on laboratory examination indicators and elastography technology that can quantify liver stiffness have some value in the evaluation of fibrosis,the diagnostic accuracy and characteristics of these various methods vary and cannot replace liver biopsy completely.In recent years,some liver-protective drugs and proprietary Chinese traditional medicines have been proven to delay or reverse chronic liver fibrosis.Nevertheless,their efficacy and safety for LT recipients need to be further verified.This article reviews the diagnosis and treatment of graft fibrosis after LT to provide a reference for improving the overall survival rate of LT recipients.
基金supported by Innovation Program for Quantum Science and Technology (2021ZD0300200)Shanghai Municipal Science and Technology Major Project (2019SHZDZX01)+13 种基金Special funds from Jinan Science and Technology Bureau and Jinan High Tech Zone Management Committeethe Chinese Academy of Sciences (CAS)Anhui Initiative in Quantum Information TechnologiesTechnology Committee of Shanghai MunicipalityNatural Science Foundation of Shandong Province (ZR202209080019)Key-Area Research and Development Program of Guangdong Provice (2020B0303030001)supported in part by the Japanese MEXT Quantum Leap Flagship Program (MEXT Q-LEAP,JPMXS0118069605)the support from the Youth Talent Lifting Project (2020-JCJQ-QT-030)the National Natural Science Foundation of China (12274464,and 11905294)China Postdoctoral Science Foundationthe Open Research Fund from State Key Laboratory of High Performance Computing of China (201901-01)supported by Shanghai Rising-Star Program (23QA1410000)the Youth Innovation Promotion Association of CAS (2022460)the support from THE XPLORER PRIZE。
基金the National Key R&D Program of China(2017YFA0304300),the Chinese Academy of Sciences,Anhui Initiative in Quantum Information Technologies,Technology Committee of Shanghai Municipality,National Natural Science Foundation of China(11905217,11774326,and 11905294)‘Shang-hai Municipal Science and Technology Major Project(2019SHZDZX01)’Natural Science Foundation of Shanghai(19ZR1462700)‘Key-Area Research and Development Program of Guangdong Province(2020B0303030001)’the Youth Talent Lifting Project(2020-JCJQ-QT-030)。
文摘To ensure a long-term quantum computational advantage,the quantum hardware should be upgraded to withstand the competition of continuously improved classical algorithms and hardwares.Here,we demonstrate a superconducting quantum computing systems Zuchongzhi 2.1,which has 66 qubits in a two-dimensional array in a tunable coupler architecture.The readout fidelity of Zuchongzhi 2.1 is considerably improved to an average of 97.74%.The more powerful quantum processor enables us to achieve larger-scale random quantum circuit sampling,with a system scale of up to 60 qubits and 24 cycles,and fidelity of FXEB=(3·66±0·345)×10^(-4).The achieved sampling task is about 6 orders of magnitude more difficult than that of Sycamore[Nature 574,505(2019)]in the classic simulation,and 3 orders of magnitude more difficult than the sampling task on Zuchongzhi 2.0[arXiv:2106.14734(2021)].The time consumption of classically simulating random circuit sampling experiment using state-of-the-art classical algorithm and supercomputer is extended to tens of thousands of years(about 4·8×104years),while Zuchongzhi 2.1 only takes about 4.2 h,thereby significantly enhancing the quantum computational advantage.
文摘To the Editor,Liver transplantation(LT)is the only curative therapy for patients with end‐stage liver disease.1 Due to the high incidence of metabolic syndrome after LT,nonalcoholic fatty liver disease(NAFLD)has gradually become an essential cause of post‐LT fibrosis.2 Liver fibrosis can progress to liver cirrhosis and carries the risk of developing hepatocellular carcinoma(HCC),which adversely affects long‐term survival after LT.3,4 Early detection and active intervention for liver fibrosis after LT are crucial in LT recipients.Previous studies have confirmed that transient elastography(TE)could accurately detect liver fibrosis in LT recipients by comparing TE with liver biopsy.