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An LCC-HVDC Adaptive Emergency Power Support Strategy Based on Unbalanced Power On-Line Estimation
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作者 Congshan Li Jian Guo +3 位作者 Ping He Yukun Tao Cunxiang Yang youyi wang 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2020年第2期87-96,共10页
HVDC auxiliary power control can significantly improve the transient stability of AC/DC power grid.An HVDC adaptive emergency power support method based on unbalanced power on line estimation is proposed in this paper... HVDC auxiliary power control can significantly improve the transient stability of AC/DC power grid.An HVDC adaptive emergency power support method based on unbalanced power on line estimation is proposed in this paper.By establishing the extended state equation of the system,the on line dynamic estimation of unbalanced power of the system was realized.On this basis,power support was realized based on the principle of the ladder increment.The optimal DC was selected by the power support factor,and the emergency power support controller was installed on the DC.This emergency power support method can realize dynamic optimal power support with minimized control cost.The three infeed HVDC system was built on PSCAD.The simulation results show the effectiveness of the proposed method. 展开更多
关键词 EMERGENCY POWER support unbalanced POWER extended state OBSERVER LADDER increasing PRINCIPLE multi infeed HVDC system
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Preparation of a highly specific and sensitive monoclonal antibody against tilmicosin and its application in lateral flow immunoassay
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作者 youyi wang Qingyue Li +7 位作者 Guanghua Liang Huayun Li Zizhe Li Tian Gao Lianjun Song Xianqing Huang Dapeng Peng Xiya Zhang 《One Health Advances》 2023年第1期1-9,共9页
To reduce the false positive results caused by cross reactivity of the antibodies with other structural analogues,it is crucial to prepare a high specificity and sensitivity antibody against target for developing an a... To reduce the false positive results caused by cross reactivity of the antibodies with other structural analogues,it is crucial to prepare a high specificity and sensitivity antibody against target for developing an accurate immunoassay.In this study,tilmicosin(TM)was selected as a model molecule.Firstly,two-dimensional similarity,electrostatic potential energy,mulliken atomic charges and overlapping of different haptens with TM were calculated using Gaussian 09W and Discovery studio,and the newly designed TM-HS was selected as the optimal hapten.Furthermore,a monoclonal antibody(mAb 12C8)was produced with the half maximal inhibitory concentration(IC50)of 0.36 ng/mL,and negligible cross-reactivity(CR)with other antibiotics.Finally,a lateral flow immunoassay(LFA)for the detection of TM based on amorphous carbon nanoparticles(ACNPs)labeled mAb 12C8 was developed by the reflectance value under natural light.The recoveries of TM ranged from 83.18%to 103.25%with a coefficient of variation(CV)<12.47%.The results showed that the cut-off value of TM in milk samples was 1 ng/mL,and the limits of detection(LODs)for chicken muscle,bovine muscle,porcine muscle and porcine liver samples were 5.23,5.98,6.85 and 7.31μg/kg,respectively.In addition,40 real samples were tested by the LFA,and the detection results were consisted with that of high-performance liquid chromatography-UV detector(HPLC-UV).Those results indicated that the developed LFA is an accurate and useful tool for on-site screening of TM in milk and animal tissues. 展开更多
关键词 Hapten design Monoclonal antibody High sensitivity TILMICOSIN Lateral flow immunoassay
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