The catalytic properties of a series of (dppe) MCl2 [M = Fe(II), Co(II), Ni(II)] in combination with EAO (ethylaluminoxane) for ethylene oligomerization have been investigated. Treatment of the bidentate phosphine met...The catalytic properties of a series of (dppe) MCl2 [M = Fe(II), Co(II), Ni(II)] in combination with EAO (ethylaluminoxane) for ethylene oligomerization have been investigated. Treatment of the bidentate phosphine metal complexes with EAO in toluene generated in situ active catalysts which catalyze oligomerizaton of ethylene to low-carbon olefins. The effects of reaction temperature, ratios of n(Al) : n(M) and reaction periods on catalytic activity and product distribution have been studied. The activity of cobalt complex with EAO at 200C was 4021 g/g(Co)h, and the selectivity of C4-10 olefins is 95.5%.展开更多
A new series of benzamide derivatives as glucokinase activators （GKAs） were designed and synthesized, and their activation for glucokinase were evaluated by the preliminary glucokinase activity assay. The structure-...A new series of benzamide derivatives as glucokinase activators （GKAs） were designed and synthesized, and their activation for glucokinase were evaluated by the preliminary glucokinase activity assay. The structure-activity relationship （SAR） is discussed. The result shows that compound 12d and 12h have potent activity reference drug RO-28-1675.展开更多
文摘The catalytic properties of a series of (dppe) MCl2 [M = Fe(II), Co(II), Ni(II)] in combination with EAO (ethylaluminoxane) for ethylene oligomerization have been investigated. Treatment of the bidentate phosphine metal complexes with EAO in toluene generated in situ active catalysts which catalyze oligomerizaton of ethylene to low-carbon olefins. The effects of reaction temperature, ratios of n(Al) : n(M) and reaction periods on catalytic activity and product distribution have been studied. The activity of cobalt complex with EAO at 200C was 4021 g/g(Co)h, and the selectivity of C4-10 olefins is 95.5%.
基金financially supported by the National Nature Science Foundation of China(No.30572256)
文摘A new series of benzamide derivatives as glucokinase activators （GKAs） were designed and synthesized, and their activation for glucokinase were evaluated by the preliminary glucokinase activity assay. The structure-activity relationship （SAR） is discussed. The result shows that compound 12d and 12h have potent activity reference drug RO-28-1675.
