One new Iriterpene saponin was isolated from Panaxjaponicus C. A. Meyer var major (Burk.) C. Y. Wu et K. M. Feng, and established as oleanolic acid 3-O-[β-D-glucopyranosyl-(1 →2)-β-D-glucuronopyranosyl-6'-O-n-...One new Iriterpene saponin was isolated from Panaxjaponicus C. A. Meyer var major (Burk.) C. Y. Wu et K. M. Feng, and established as oleanolic acid 3-O-[β-D-glucopyranosyl-(1 →2)-β-D-glucuronopyranosyl-6'-O-n-butyl ester] which showed mod- erate antitumor activities against the A2780 cells and OVCAR-3 cells. Its structure was established by means of spectral data, particularly NMR, including HSQC and HMBC techniques.展开更多
a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside o...a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside on the basis of spectral analysis and chemical evidence.展开更多
Two new cucurbitane-type triterpenoids,(23E)-5β,19-epoxycucurbita-6,23,25-triene-3β-ol(1) and(19R,23E)-5/β,19-epoxy- 19-ethoxycucurbita-6,23-diene^3β,25-diol(2),together with three known compounds,have bee...Two new cucurbitane-type triterpenoids,(23E)-5β,19-epoxycucurbita-6,23,25-triene-3β-ol(1) and(19R,23E)-5/β,19-epoxy- 19-ethoxycucurbita-6,23-diene^3β,25-diol(2),together with three known compounds,have been isolated from the fruit of Momordica charantia L.Their structures were determined on the basis of spectral analysis.Their cytotoxic activity was tested on 5 cancer cell lines,MCF-7,HepG2,Dul45,Colon205 and HL-60 by MTT assay.Compounds 1,3 and 4 showed weak cytotoxicity.展开更多
Two new sapogenins,named(20S,24R)-3β,20,21β,25-tetrahydroxy-21,24-cyclodammarane(1)and 3β-hydroxyetio-17β-dammaranic acid(2),were isolated from the alkaline hydrolysate of Gynostemma pentaphyllum saponins.Th...Two new sapogenins,named(20S,24R)-3β,20,21β,25-tetrahydroxy-21,24-cyclodammarane(1)and 3β-hydroxyetio-17β-dammaranic acid(2),were isolated from the alkaline hydrolysate of Gynostemma pentaphyllum saponins.Their structures were elucidated by spectroscopic methods.展开更多
基金financially supported by Chinese Academy of Nutritional Sciences,Shanghai Institutes for Biological Sciences
文摘One new Iriterpene saponin was isolated from Panaxjaponicus C. A. Meyer var major (Burk.) C. Y. Wu et K. M. Feng, and established as oleanolic acid 3-O-[β-D-glucopyranosyl-(1 →2)-β-D-glucuronopyranosyl-6'-O-n-butyl ester] which showed mod- erate antitumor activities against the A2780 cells and OVCAR-3 cells. Its structure was established by means of spectral data, particularly NMR, including HSQC and HMBC techniques.
文摘a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside on the basis of spectral analysis and chemical evidence.
基金supported by E&T Modern Center for Natural Products of Liaoning Province of China (No.2008402021)
文摘Two new cucurbitane-type triterpenoids,(23E)-5β,19-epoxycucurbita-6,23,25-triene-3β-ol(1) and(19R,23E)-5/β,19-epoxy- 19-ethoxycucurbita-6,23-diene^3β,25-diol(2),together with three known compounds,have been isolated from the fruit of Momordica charantia L.Their structures were determined on the basis of spectral analysis.Their cytotoxic activity was tested on 5 cancer cell lines,MCF-7,HepG2,Dul45,Colon205 and HL-60 by MTT assay.Compounds 1,3 and 4 showed weak cytotoxicity.
基金financially supported by E&T Modern Center for Natural Products of Liaoning Province of China (No.2008402021)
文摘Two new sapogenins,named(20S,24R)-3β,20,21β,25-tetrahydroxy-21,24-cyclodammarane(1)and 3β-hydroxyetio-17β-dammaranic acid(2),were isolated from the alkaline hydrolysate of Gynostemma pentaphyllum saponins.Their structures were elucidated by spectroscopic methods.