The Truong Son Fold Belt,located at the northeastern margin of the Indochina Block,is considered to be tectonically linked to the subduction of the Paleotethys Ocean and subsequent collision.Sepon is one of the most i...The Truong Son Fold Belt,located at the northeastern margin of the Indochina Block,is considered to be tectonically linked to the subduction of the Paleotethys Ocean and subsequent collision.Sepon is one of the most important super large deposits of the Truong Son Fold Belt.Our LA-ICP-MS zircon U-Pb dating results show that granodiorite porphyry samples from the Sepon deposit have ages of 302.1-4-2.9 Ma, which is a crucial phase for magmatic-tectonical activities from the Late Carboniferous to Early Permian and has avital influence on the mineralization of copper and gold.Zircon from granodiorite porphyry yields εHf (t)values of 4.32 to 9.64,and TDM2 has an average age of 914 Ma,suggesting that the source of the granodiorite porphyry in the region were mainly mantle components but underwent mixing and contamination of crust materials.The Ce^4+/Ce^3+ value of zircon in the granodiorite porphyry varys greatly from 2.4 to 1438.29,which shows magma mixing might occur.Considering the characteristics of trace elements in the zircon and the whole rock geochemical characteristics of intrusion rocks as well as the characteristics of regional volcanic-sedimentary association,it is indicated that the tectonic setting may be the continental arc environment.The Sepon Au-Cu deposit is derived from emplacement of calc-alkaline intermediate-acid magma with coming from deep sources in the subduction process of the Paleotethys Ocean,forming porphyry Mo-Cu,skam Cu-Au mineralization and a hydrothermal sedimentary-hosted Au mineralization in the wall rocks.展开更多
The Narooma-Batemans Bay(NBB)area along the southeast coast of Australia is a part of the eastern zone of the Early Paleozoic Lachlan Orogen.In the NBB,a set of rock association consisting of turbidites,siliceous rock...The Narooma-Batemans Bay(NBB)area along the southeast coast of Australia is a part of the eastern zone of the Early Paleozoic Lachlan Orogen.In the NBB,a set of rock association consisting of turbidites,siliceous rock,basic lava,and argillaceous melange zone is mainly developed.According to systematic field geological survey,the deformation of 3 stages(D1,D2,and D3)was identified in the NBB.At stage D1,with the original bedding S0 in a nearly east-west trending as the deformation plane,tight folds,isoclinal folds,and other structures formed in the NBB accompanied by structural transposition.As a result,crenulation cleavage developed along the axial plane of the folds and schistosity S1 formed.At stage D2,with north-south-trending schistosity S1 as the deformation plane,a large number of asymmetrical folds and rotated porphyroclasts formed owing to thrusting and shear.At stage D3,leftlateral strike-slip occurred along the main north-south-trending schistosity.Based on the analysis of the characteristics of tectonic deformation in the NBB and summary of previous research results,it is determined that the early-stage(D1)deformation is related to Ordovician Macquarie arc-continent collision and the deformation at stages D2 and D3 is the result of the westward subduction of Paleo-Pacific Plate.That is,it is not the continuous westward subduction of the Paleo-Pacific Plate that constitutes the evolution model of the NBB as previously considered.展开更多
In order to investigate the characteristics and mechanisms of subthreshold voltage hysteresis(ΔV_(th,sub)) of 4 H-SiC metal-oxide-semiconductor field-effect transistors(MOSFETs),4 H-SiC planar and trench MOSFETs and ...In order to investigate the characteristics and mechanisms of subthreshold voltage hysteresis(ΔV_(th,sub)) of 4 H-SiC metal-oxide-semiconductor field-effect transistors(MOSFETs),4 H-SiC planar and trench MOSFETs and corresponding P-type planar and trench metal-oxide-semiconductor(MOS) capacitors are fabricated and characterized.Compared with planar MOSFEF,the trench MOSFET shows hardly larger ΔV_(th,sub) in wide temperature range from 25 0 C to 300 0 C.When operating temperature range is from 25 ℃ to 300 ℃,the off-state negative V_(gs) of planar and trench MOSFETs should be safely above-4 V and-2 V,respectively,to alleviate the effect of ΔV_(th,sub) on the normal operation.With the help of P-type planar and trench MOS capacitors,it is confirmed that the obvious ΔV_(th,sub) of 4 H-SiC MOSFET originates from the high density of the hole interface traps between intrinsic Fermi energy level(E_(i)) and valence band(E_(v)).The maximumΔV_(th,sub) of trench MOSFET is about twelve times larger than that of planar MOSFET,owing to higher density of interface states(D_(it)) between E_(i) and E_(v).These research results will be very helpful for the application of 4 H-SiC MOSFET and the improvement of ΔV_(th,sub) of 4 H-SiC MOSFET,especially in 4 H-SiC trench MOSFET.展开更多
Aim: To examine the expression of prostate cancer antigen-1 (PCA-1) in prostate cancer (PCa) and to validate it as a potential marker for diagnosis of PCa. Methods: In situ hybridization analysis of PCA-1 mRNA e...Aim: To examine the expression of prostate cancer antigen-1 (PCA-1) in prostate cancer (PCa) and to validate it as a potential marker for diagnosis of PCa. Methods: In situ hybridization analysis of PCA-1 mRNA expression was performed on 40 benign prostate hyperplasia (BPH), 16 high-grade prostatic intraepithelial neoplasm (HG-PIN), 74 PCa and 34 other malignant carcinoma specimens. The level of PCA- 1 expression was semiquanfitatively scored by assessing both the percentage and intensity of PCA- 1 positive staining cells in the specimens. We then compared the PCA-1 expression between BPH, HG-PIN and PCa and evaluated the correlation of PCA-1 expression level with clinical parameters of PCa. Results: PCA-1 mRNA was expressed in the majority of both PCa and HG-PIN specimens but not in BPH and other malignant carcinoma. The expression level of PCA-1 increased along with a high Gleason score (P 〈 0.05), and was unrelated to other clinical parameters of PCa (all P 〉 0.05). Conclusion: The data suggest that PCA-1 might be a novel diagnostic marker for PCa, and that increased PCA-1 expression might denote more aggressive variants of PCa.展开更多
基金the National Science Foundation of China (41373036, 41002027)the Geological Survey of China Geological Survey Project (121201103000150006,121201066307).
文摘The Truong Son Fold Belt,located at the northeastern margin of the Indochina Block,is considered to be tectonically linked to the subduction of the Paleotethys Ocean and subsequent collision.Sepon is one of the most important super large deposits of the Truong Son Fold Belt.Our LA-ICP-MS zircon U-Pb dating results show that granodiorite porphyry samples from the Sepon deposit have ages of 302.1-4-2.9 Ma, which is a crucial phase for magmatic-tectonical activities from the Late Carboniferous to Early Permian and has avital influence on the mineralization of copper and gold.Zircon from granodiorite porphyry yields εHf (t)values of 4.32 to 9.64,and TDM2 has an average age of 914 Ma,suggesting that the source of the granodiorite porphyry in the region were mainly mantle components but underwent mixing and contamination of crust materials.The Ce^4+/Ce^3+ value of zircon in the granodiorite porphyry varys greatly from 2.4 to 1438.29,which shows magma mixing might occur.Considering the characteristics of trace elements in the zircon and the whole rock geochemical characteristics of intrusion rocks as well as the characteristics of regional volcanic-sedimentary association,it is indicated that the tectonic setting may be the continental arc environment.The Sepon Au-Cu deposit is derived from emplacement of calc-alkaline intermediate-acid magma with coming from deep sources in the subduction process of the Paleotethys Ocean,forming porphyry Mo-Cu,skam Cu-Au mineralization and a hydrothermal sedimentary-hosted Au mineralization in the wall rocks.
基金This research was supported financially by the National Natural Science(41702213)Fundamental Research Funds of the Chinese Academy of Geological Sciences(K1614,YYWF201709).
文摘The Narooma-Batemans Bay(NBB)area along the southeast coast of Australia is a part of the eastern zone of the Early Paleozoic Lachlan Orogen.In the NBB,a set of rock association consisting of turbidites,siliceous rock,basic lava,and argillaceous melange zone is mainly developed.According to systematic field geological survey,the deformation of 3 stages(D1,D2,and D3)was identified in the NBB.At stage D1,with the original bedding S0 in a nearly east-west trending as the deformation plane,tight folds,isoclinal folds,and other structures formed in the NBB accompanied by structural transposition.As a result,crenulation cleavage developed along the axial plane of the folds and schistosity S1 formed.At stage D2,with north-south-trending schistosity S1 as the deformation plane,a large number of asymmetrical folds and rotated porphyroclasts formed owing to thrusting and shear.At stage D3,leftlateral strike-slip occurred along the main north-south-trending schistosity.Based on the analysis of the characteristics of tectonic deformation in the NBB and summary of previous research results,it is determined that the early-stage(D1)deformation is related to Ordovician Macquarie arc-continent collision and the deformation at stages D2 and D3 is the result of the westward subduction of Paleo-Pacific Plate.That is,it is not the continuous westward subduction of the Paleo-Pacific Plate that constitutes the evolution model of the NBB as previously considered.
基金Project supported by the National Key Research and Development Program of China(Grant No.2017YFB0903203)the National Natural Science Foundation of China(Grant No.62004033)China Postdoctoral Science Foundation(Grant No.2020M683287)。
文摘In order to investigate the characteristics and mechanisms of subthreshold voltage hysteresis(ΔV_(th,sub)) of 4 H-SiC metal-oxide-semiconductor field-effect transistors(MOSFETs),4 H-SiC planar and trench MOSFETs and corresponding P-type planar and trench metal-oxide-semiconductor(MOS) capacitors are fabricated and characterized.Compared with planar MOSFEF,the trench MOSFET shows hardly larger ΔV_(th,sub) in wide temperature range from 25 0 C to 300 0 C.When operating temperature range is from 25 ℃ to 300 ℃,the off-state negative V_(gs) of planar and trench MOSFETs should be safely above-4 V and-2 V,respectively,to alleviate the effect of ΔV_(th,sub) on the normal operation.With the help of P-type planar and trench MOS capacitors,it is confirmed that the obvious ΔV_(th,sub) of 4 H-SiC MOSFET originates from the high density of the hole interface traps between intrinsic Fermi energy level(E_(i)) and valence band(E_(v)).The maximumΔV_(th,sub) of trench MOSFET is about twelve times larger than that of planar MOSFET,owing to higher density of interface states(D_(it)) between E_(i) and E_(v).These research results will be very helpful for the application of 4 H-SiC MOSFET and the improvement of ΔV_(th,sub) of 4 H-SiC MOSFET,especially in 4 H-SiC trench MOSFET.
文摘Aim: To examine the expression of prostate cancer antigen-1 (PCA-1) in prostate cancer (PCa) and to validate it as a potential marker for diagnosis of PCa. Methods: In situ hybridization analysis of PCA-1 mRNA expression was performed on 40 benign prostate hyperplasia (BPH), 16 high-grade prostatic intraepithelial neoplasm (HG-PIN), 74 PCa and 34 other malignant carcinoma specimens. The level of PCA- 1 expression was semiquanfitatively scored by assessing both the percentage and intensity of PCA- 1 positive staining cells in the specimens. We then compared the PCA-1 expression between BPH, HG-PIN and PCa and evaluated the correlation of PCA-1 expression level with clinical parameters of PCa. Results: PCA-1 mRNA was expressed in the majority of both PCa and HG-PIN specimens but not in BPH and other malignant carcinoma. The expression level of PCA-1 increased along with a high Gleason score (P 〈 0.05), and was unrelated to other clinical parameters of PCa (all P 〉 0.05). Conclusion: The data suggest that PCA-1 might be a novel diagnostic marker for PCa, and that increased PCA-1 expression might denote more aggressive variants of PCa.