Multi-stage igneous rocks developed in the recently discovered Huoluotai Cu-(Mo)deposit provide new insights into the controversial late Mesozoic geodynamic evolution of the northern segment of the Great Xing’an Rang...Multi-stage igneous rocks developed in the recently discovered Huoluotai Cu-(Mo)deposit provide new insights into the controversial late Mesozoic geodynamic evolution of the northern segment of the Great Xing’an Range(NSGXR).Zircon U-Pb dating suggests that the monzogranite,ore-bearing granodiorite porphyry,diorite porphyry,and granite porphyry in the deposit were emplaced at 179.5±1.6,148.9±0.9,146.1±1.3,and 142.2±1.5 Ma,respectively.The Re-Os dating of molybdenite yielded an isochron age of 146.9±2.3 Ma(MSWD=0.27).The Jurassic adakitic monzogranite and granodiorite porphyry are characterized by high SiO_(2)and Na_(2)O contents,low K_(2)O/Na_(2)O ratios,low Mg O,Cr,and Ni contents,low zirconεHf(t)values relative to depleted mantle,and relatively high Th contents.They were produced by partial melting of a subducted oceanic slab,with involvement of marine sediments in the magma source and limited interaction with mantle peridotites during magma ascent.The Late Jurassic diorite porphyry is characterized by moderate SiO_(2) contents,high Mg O,Cr,and Ni contents,and positive dominatedεHf(t)values,indicating it was produced by partial melting of a subduction-modified lithospheric mantle wedge and underwent limited crustal contamination during magma ascent.The early Early Cretaceous adakitic granite porphyry shows high SiO_(2) and K_(2)O contents and K_(2)O/Na_(2)O ratios,low Mg O,Cr,and Ni contents,enriched Sr-Nd isotopic compositions,and slightly positive zirconεHf(t)values,suggesting it was produced by partial melting of thickened mafic lower crust.The NSGXR experienced a tectonic history that involved flat-slab subduction(200-160 Ma),and tearing and collapse(150-145 Ma)of the Mongol-Okhotsk oceanic lithosphere.The period of magmatic quiescence from ca.160 to 150 Ma was a response to flat-slab subduction of the Mongol-Okhotsk oceanic lithosphere.Crustal thickening in the NSGXR(145-133 Ma)was due to the collision between the Amuria Block and the Siberian Craton.展开更多
Background： Nontraumatic osteonecrosis of the femoral head （NONFH） is a debilitating disease that represents a significant financial burden for both individuals and healthcare systems. Despite its significance, how...Background： Nontraumatic osteonecrosis of the femoral head （NONFH） is a debilitating disease that represents a significant financial burden for both individuals and healthcare systems. Despite its significance, however, its prevalence in the Chinese general population remains unknown. This study aimed to investigate the prevalence of NONFH and its associated risk factors in the Chinese population. Methods： A nationally representative survey of 30,030 respondents was undertaken from June 2012 to August 2013. All participants underwent a questionnaire investigation, physical examination of hip, and bilateral hip joint X-ray and/or magnetic resonance imaging exalnination. Blood samples were taken after overnight fasting to test serum total cholesterol, triglyceride, and high-density lipoprotein （HDL） and low-density lipoprotein （LDL） levels. We then used multivariate logistic regression analysis to investigate the associations between various metabolic, demographic, and lifestyle-related variables and NONFH. Results： NONFH was diagnosed in 218 subjects （0.725%） and the estimated NONFH cases were 8.12 million among Chinesepeople aged 15 years and over. The prevalence of NONFH was significantly higher in males than in females （1.02% vs. 0.51%, x^2 = 24.997, P 〈 0.001 ）. Among NONFH patients, North residents were subjected to higher prevalence of NONFH than that of South residents （0.85% vs. 0.61%,x^2= 5.847, P = 0.016）. Our multivariate regression analysis showed that high blood levels oftriglycerides, total cholesterol, LDL-cholesterol, and non-H DL-cholesterol, male, urban residence, family history of osteonecrosis of the femoral head. heavy smoking, alcohol abuse and glucocorticoid intake, overweight, and obesity were all significantly associated with an increased risk of NONFH. Conclusions： Our findings highlight that NONFH is a significantpublic health challenge in China and underscore the need for policy measures on the national level. Furthermore, NONFH shares a number of risk factors with atherosclerosis.展开更多
基金funded by the Natural Science Foundation of Jilin Province(No.20180101089JC)Key Projects of Science and Technology Development Plan of Jilin Province(No.20100445)+5 种基金National Key R&D Program of China(2017YFC0601304)the Natural Science Foundation of Liaoning Province(2020-BS-258)the Department of Education of Liaoning Province(LJ2020JCL010)a Discipline Innovation Team Project of Liaoning Technical University(LNTU20TD-14)Graduate Innovation Research Project of Jilin University(Grant NO.101832020CX201)Heilongjiang Research Project of Land and Resources(201605,201704)。
文摘Multi-stage igneous rocks developed in the recently discovered Huoluotai Cu-(Mo)deposit provide new insights into the controversial late Mesozoic geodynamic evolution of the northern segment of the Great Xing’an Range(NSGXR).Zircon U-Pb dating suggests that the monzogranite,ore-bearing granodiorite porphyry,diorite porphyry,and granite porphyry in the deposit were emplaced at 179.5±1.6,148.9±0.9,146.1±1.3,and 142.2±1.5 Ma,respectively.The Re-Os dating of molybdenite yielded an isochron age of 146.9±2.3 Ma(MSWD=0.27).The Jurassic adakitic monzogranite and granodiorite porphyry are characterized by high SiO_(2)and Na_(2)O contents,low K_(2)O/Na_(2)O ratios,low Mg O,Cr,and Ni contents,low zirconεHf(t)values relative to depleted mantle,and relatively high Th contents.They were produced by partial melting of a subducted oceanic slab,with involvement of marine sediments in the magma source and limited interaction with mantle peridotites during magma ascent.The Late Jurassic diorite porphyry is characterized by moderate SiO_(2) contents,high Mg O,Cr,and Ni contents,and positive dominatedεHf(t)values,indicating it was produced by partial melting of a subduction-modified lithospheric mantle wedge and underwent limited crustal contamination during magma ascent.The early Early Cretaceous adakitic granite porphyry shows high SiO_(2) and K_(2)O contents and K_(2)O/Na_(2)O ratios,low Mg O,Cr,and Ni contents,enriched Sr-Nd isotopic compositions,and slightly positive zirconεHf(t)values,suggesting it was produced by partial melting of thickened mafic lower crust.The NSGXR experienced a tectonic history that involved flat-slab subduction(200-160 Ma),and tearing and collapse(150-145 Ma)of the Mongol-Okhotsk oceanic lithosphere.The period of magmatic quiescence from ca.160 to 150 Ma was a response to flat-slab subduction of the Mongol-Okhotsk oceanic lithosphere.Crustal thickening in the NSGXR(145-133 Ma)was due to the collision between the Amuria Block and the Siberian Craton.
文摘Background： Nontraumatic osteonecrosis of the femoral head （NONFH） is a debilitating disease that represents a significant financial burden for both individuals and healthcare systems. Despite its significance, however, its prevalence in the Chinese general population remains unknown. This study aimed to investigate the prevalence of NONFH and its associated risk factors in the Chinese population. Methods： A nationally representative survey of 30,030 respondents was undertaken from June 2012 to August 2013. All participants underwent a questionnaire investigation, physical examination of hip, and bilateral hip joint X-ray and/or magnetic resonance imaging exalnination. Blood samples were taken after overnight fasting to test serum total cholesterol, triglyceride, and high-density lipoprotein （HDL） and low-density lipoprotein （LDL） levels. We then used multivariate logistic regression analysis to investigate the associations between various metabolic, demographic, and lifestyle-related variables and NONFH. Results： NONFH was diagnosed in 218 subjects （0.725%） and the estimated NONFH cases were 8.12 million among Chinesepeople aged 15 years and over. The prevalence of NONFH was significantly higher in males than in females （1.02% vs. 0.51%, x^2 = 24.997, P 〈 0.001 ）. Among NONFH patients, North residents were subjected to higher prevalence of NONFH than that of South residents （0.85% vs. 0.61%,x^2= 5.847, P = 0.016）. Our multivariate regression analysis showed that high blood levels oftriglycerides, total cholesterol, LDL-cholesterol, and non-H DL-cholesterol, male, urban residence, family history of osteonecrosis of the femoral head. heavy smoking, alcohol abuse and glucocorticoid intake, overweight, and obesity were all significantly associated with an increased risk of NONFH. Conclusions： Our findings highlight that NONFH is a significantpublic health challenge in China and underscore the need for policy measures on the national level. Furthermore, NONFH shares a number of risk factors with atherosclerosis.
