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CO_2激光联合等离子射频消融术对早期声门型喉癌相关细胞因子水平的影响 被引量:35
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作者 董玉科 李玉杰 黄炜 《中国现代医学杂志》 CAS 2019年第6期69-72,共4页
目的观察二氧化碳CO_2激光联合等离子射频消融术(PRA)治疗早期声门型喉癌患者前后血管内皮生长因子(VEGF)、一氧化氮NO及肿瘤坏死因子α(TNF-α)水平变化和疗效。方法选取早期声门型喉癌患者298例作为研究对象,随机分为观察组与对照组,... 目的观察二氧化碳CO_2激光联合等离子射频消融术(PRA)治疗早期声门型喉癌患者前后血管内皮生长因子(VEGF)、一氧化氮NO及肿瘤坏死因子α(TNF-α)水平变化和疗效。方法选取早期声门型喉癌患者298例作为研究对象,随机分为观察组与对照组,每组149例。对照组患者接受传统喉裂开术;观察组患者接受CO_2激光联合PRA。采用酶联免疫吸附法测定血清VEGF及TNF-α,硝酸还原酶法测定NO。分别收集两组患者术后恢复情况和1年后并发症发生情况。结果两组患者术前VEGF、NO及TNF-α水平比较,差异无统计学意义(P>0.05);而术后VEGF、NO及TNF-α水平比较,差异有统计学意义(P <0.05)。观察组手术时间、住院时间低于对照组(P <0.05),黏膜恢复情况较对照组好;观察组并发症发生率低于对照组(P <0.05)。结论 CO_2激光联合PRA治疗早期声门型喉癌能有效减少手术创伤,改善患者预后,降低患者血清VEGF、NO及TNF-α水平。 展开更多
关键词 声门型喉癌/喉肿瘤 治疗效果 血管内皮生长因子类 一氧化氮 肿瘤坏死因子α
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Subperiosteal orbital hematoma concomitant with abscess in a patient with sinusitis:A case report
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作者 Xi-Hao Hu Chi Zhang +1 位作者 yu-ke dong Tie-Chuan Cong 《World Journal of Clinical Cases》 SCIE 2022年第28期10326-10331,共6页
BACKGROUND Sinusitis-derived subperiosteal orbital collection is uncommon and is usually diagnosed as subperiosteal orbital abscess or,rarely,as hematoma.We report a unique and even rarer case of subperiosteal orbital... BACKGROUND Sinusitis-derived subperiosteal orbital collection is uncommon and is usually diagnosed as subperiosteal orbital abscess or,rarely,as hematoma.We report a unique and even rarer case of subperiosteal orbital collection,which is actually a complication of hematoma and abscess.CASE SUMMARY A 26-year-old female presented with left eyeball pain and ipsilateral chemosis.She had no history of head trauma or upper respiratory infection.Her blood cell count showed an increase in leukocytes.Fiberoptic rhinolaryngoscopy revealed only mucosal edema of the left olfactory crest without apparent discharge.The computed tomography scan results showed an opaque left posterior ethmoid cell with a thickened bony shell and fusiform changes in the periosteal elevation of the medial wall of the left orbit.Emergent surgery revealed an ethmoid mucocele complicated with subperiosteal orbital hematoma and abscess.The pathology of the lamina papyracea between the mucocele and subperiosteal collection was necrotic,and the overlying mucosa was de-epithelialized.CONCLUSION Subperiosteal orbital hematoma with abscess in a patient with sinusitis adds to the current knowledge of orbital complications of sinusitis. 展开更多
关键词 Subperiosteal orbital hematoma ABSCESS SINUSITIS Mucocele Surgery Case report
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