AIM:To evaluate the clinical effect of a new surgery technique(covering corneal stromal lenticule,CSL)for macular hole(MH)in pathological myopia.METHODS:This was a prospective non-randomized series case study.Fourteen...AIM:To evaluate the clinical effect of a new surgery technique(covering corneal stromal lenticule,CSL)for macular hole(MH)in pathological myopia.METHODS:This was a prospective non-randomized series case study.Fourteen eyes of 14 patients whose axial length were more than 29 mm and suffered from MH and macular hole retinal detachment(MHRD)were included in this study.All cases were treated with 25-gauge pars plana vitrectomy(PPV)with internal limiting membrane(ILM)peeling,covering CSL and C_(3)F_(8) gas tamponade.These cases were followed for 6mo,and the best-corrected visual acuity(BCVA),healing status of MH,the reattached rate of retinal detachment(RD),and reoperation rate were analyzed.RESULTS:All cases were successfully performed the surgery and the postoperative follow-up was completed.After surgery,MHs were healed in all 14 eyes(100%,14/14)after assessed by optical coherence tomography.The reattachment of retina was achieved in all 6 eyes(100%,6/6)with MHRD.BCVA was improved in 12 eyes(85.71%,12/14),and had no significant change in 2 eyes(14.29%,2/14).The overall mean BCVA was improved from 1.80±0.77 to 0.82±0.46 logMAR(F=10.46,P<0.01).No serious complications occurred in all cases.CONCLUSION:The new surgery technique(covering CSL)has high reattached rate of RD and high healing rate of MH in pathological myopia in the preliminary study.And it can effectively improve the visual function of patients.This new technique offers meaningful new ideas for treating refractory MH in pathological myopia.展开更多
On March 11,2020,the World Health Organization announced that the current outbreak of coronavirus disease 2019(COVID-19)is a global pandemic.[1]COVID-19,an acute respiratory contagious disease to which all people seem...On March 11,2020,the World Health Organization announced that the current outbreak of coronavirus disease 2019(COVID-19)is a global pandemic.[1]COVID-19,an acute respiratory contagious disease to which all people seem to be susceptible,is caused by 2019 novel coronavirus(2019-nCoV).The patient zero for this pandemic is unknown.Early epidemiology estimates suggest that the basic reproduction number(R0)for COVID-19 is 2.3,with a serial interval of 7.5 days.[2]Chinese doctors and scientists issued warnings of a global pandemic at the initial phase.[3]Unfortunately,the disease spread widely.Outbreaks and numerous new COVID-19 cases are reported daily around the world,causing public panic.To April 18,2020,there have been more than 2,200,000 confirmed cases and 150,000 death cases reported globally.[4]展开更多
基金Supported by Medical Research Project of Sichuan(No.S23090).
文摘AIM:To evaluate the clinical effect of a new surgery technique(covering corneal stromal lenticule,CSL)for macular hole(MH)in pathological myopia.METHODS:This was a prospective non-randomized series case study.Fourteen eyes of 14 patients whose axial length were more than 29 mm and suffered from MH and macular hole retinal detachment(MHRD)were included in this study.All cases were treated with 25-gauge pars plana vitrectomy(PPV)with internal limiting membrane(ILM)peeling,covering CSL and C_(3)F_(8) gas tamponade.These cases were followed for 6mo,and the best-corrected visual acuity(BCVA),healing status of MH,the reattached rate of retinal detachment(RD),and reoperation rate were analyzed.RESULTS:All cases were successfully performed the surgery and the postoperative follow-up was completed.After surgery,MHs were healed in all 14 eyes(100%,14/14)after assessed by optical coherence tomography.The reattachment of retina was achieved in all 6 eyes(100%,6/6)with MHRD.BCVA was improved in 12 eyes(85.71%,12/14),and had no significant change in 2 eyes(14.29%,2/14).The overall mean BCVA was improved from 1.80±0.77 to 0.82±0.46 logMAR(F=10.46,P<0.01).No serious complications occurred in all cases.CONCLUSION:The new surgery technique(covering CSL)has high reattached rate of RD and high healing rate of MH in pathological myopia in the preliminary study.And it can effectively improve the visual function of patients.This new technique offers meaningful new ideas for treating refractory MH in pathological myopia.
文摘On March 11,2020,the World Health Organization announced that the current outbreak of coronavirus disease 2019(COVID-19)is a global pandemic.[1]COVID-19,an acute respiratory contagious disease to which all people seem to be susceptible,is caused by 2019 novel coronavirus(2019-nCoV).The patient zero for this pandemic is unknown.Early epidemiology estimates suggest that the basic reproduction number(R0)for COVID-19 is 2.3,with a serial interval of 7.5 days.[2]Chinese doctors and scientists issued warnings of a global pandemic at the initial phase.[3]Unfortunately,the disease spread widely.Outbreaks and numerous new COVID-19 cases are reported daily around the world,causing public panic.To April 18,2020,there have been more than 2,200,000 confirmed cases and 150,000 death cases reported globally.[4]
