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阿芬太尼联合瑞马唑仑用于纤维支气管镜检查深度镇静的半数有效量和95%有效量 被引量:4
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作者 贾真 范叶铁 +3 位作者 任丽霞 吴育男 周斌 谭志明 《中国内镜杂志》 2023年第4期1-5,共5页
目的计算阿芬太尼与瑞马唑仑用于纤维支气管镜检查深度镇静的半数有效量(ED_(50))和95%有效量(ED_(95))。方法选择拟行纤维支气管镜检查和治疗的患者50例。用试验剂量的阿芬太尼联合瑞马唑仑进行镇静,患者所给予的阿芬太尼剂量依序贯试... 目的计算阿芬太尼与瑞马唑仑用于纤维支气管镜检查深度镇静的半数有效量(ED_(50))和95%有效量(ED_(95))。方法选择拟行纤维支气管镜检查和治疗的患者50例。用试验剂量的阿芬太尼联合瑞马唑仑进行镇静,患者所给予的阿芬太尼剂量依序贯试验法设计,首位患者给予的阿芬太尼剂量为6.000μg/kg。待患者睫毛反射消失,改良警觉/镇静评分(MOAA/S)<1分后,进行纤维支气管镜检查或治疗,记录序贯试验的结果和不良反应发生情况。结果阿芬太尼剂量对数的回归方程为Y=8.9286X-7.6429,阿芬太尼的ED_(50)为7.286μg/kg(95%CI:6.566~8.084),ED_(95)为10.154μg/kg(95%CI:8.753~22.323)。结论阿芬太尼联合瑞马唑仑用于纤维支气管镜检查镇静的ED_(50)为7.286μg/kg,ED_(95)为10.154μg/kg。该镇静方案可以安全、有效地用于纤维支气管镜的检查和治疗中。 展开更多
关键词 纤维支气管镜 中深度镇静 阿芬太尼 瑞马唑仑 半数有效量(ED50) 95%有效量(ED_(95))
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Effects of temperature acclimation on body mass and energy budget in the Chinese bulbul Pycnonotus sinensis 被引量:8
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作者 yu-nan wu Lin LIN +4 位作者 Yu-Chao XIAO Li-Meng ZHOU Meng-Si wu Hui-Ying ZHANG Jin-Song LIU 《Zoological Research》 CAS CSCD 北大核心 2014年第1期33-41,共9页
Chinese bulbuls (Pycnonotus sinensis) are small passerine birds that inhabit areas of central, southern and eastern China. Previous observations suggest that flee-living individuals of this species may change their ... Chinese bulbuls (Pycnonotus sinensis) are small passerine birds that inhabit areas of central, southern and eastern China. Previous observations suggest that flee-living individuals of this species may change their food intake in response to seasonal changes in ambient temperature. In the present study, we randomly assigned Chinese bulbuls to either a 30 ~C or 10 ~C group, and measured their body mass (BM), body temperature, gross energy intake (GEl), digestible energy intake (DEI), and the length and mass of their digestive tracts over 28 days of acclimation at these temperatures. As predicted, birds in the 30 ℃ group had lower body mass, GEI and DEI relative to those in the 10 ℃ group. The length and mass of the digestive tract was also lower in the 30 ℃ group and trends in these parameters were positively correlated with BM, GEl and DEI. These results suggest that Chinese bulbuls reduced their absolute energy demands at relatively high temperatures by decreasing their body mass, GEI and DEI, and digestive tract size. 展开更多
关键词 Body mass Energy budget Pycnonotus sinensis Temperature acclimation
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Selective and Sensitive Discrimination of Zinc and Cadmium Based on a Novel Fluorescent Porous Organic Polymer 被引量:1
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作者 yu-nan wu An-Ting Qiu +4 位作者 Zu-Qi Zhong Li-Zhi Wang Ming-Yue Yuan Heng-Xin Zhao Sai-Jin Xiao 《Journal of Analysis and Testing》 EI 2021年第3期235-241,共7页
Zinc and cadmium are two main transition metal ions and play profound important roles in environmental and human health.But the distinctive detection of these two ions is still challenging since they belong to the sam... Zinc and cadmium are two main transition metal ions and play profound important roles in environmental and human health.But the distinctive detection of these two ions is still challenging since they belong to the same periodic group and have similar chemical properties.A fluorescent bipyridine-based porous organic polymer(Bpy-POP)containing aggregation caused quenching(ACQ)units(anthracene)and metal ions recognition units(bipyridine)was synthesized through the Schiff base condensation reaction.In the DMF/H_(2)O mixtures with the water fractions of 90%,the Bpy-POP aggregated and the fluorescent Bpy-POP quenched subsequently due to the ACQ effect of anthracene in the skeleton("OFF"state).With the addition of Zn^(2+)or Cd^(2+),however,the strong coordination of the bipyridine units from the adjacent Bpy-POPs with Zn^(2+)or Cd^(2+)induced the partial dispersion of large Bpy-POP aggregates.Consequently,the fluorescence intensities enhanced dramatically as well as the fluorescence emission shifted to redder region,showing an"ON"state.Combing the fluorescence increasing efficiency and the maximum emission wavelength shift degree together,Zn^(2+)and Cd^(2+)can be selectively discriminated and quantitatively detected,which exhibits a great promising of the present Bpy-POP based method in Zn^(2+)and Cd^(2+)monitoring in real samples. 展开更多
关键词 ZINC Cadnium Porous organic polymer Aggregation caused quenching BIPYRIDINE
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