AIM: To investigate and evaluate healing patterns around flaps made with different side-cut angulations after femtosecond laser in situ keratomileusis(FS-LASIK).METHODS: Thirty-four patients(68 eyes) received a 90...AIM: To investigate and evaluate healing patterns around flaps made with different side-cut angulations after femtosecond laser in situ keratomileusis(FS-LASIK).METHODS: Thirty-four patients(68 eyes) received a 90° side-cut(n=34) or a 120° side-cut flaps(n=34) made with a femtosecond laser. One day, 1 wk, 1 and 3 mo postoperatively, side-cut scar was evaluated under slit-lamp photography according to a new grading system(Grade 0=transparent scar, 1=faint healing opacity, and 2=evident healing opacity). In vivo corneal confocal microscopy and anterior segment optical coherence tomography(AS-OCT) were used to observe wound-healing patterns around flap margin in the two groups. Sirius Scheimpflug Analyzer was also used to analyze higher order aberrations 3 mo after surgery.RESULTS: There were no significant differences in flap wound-healing patterns at each follow up between the two groups(P>0.05). Three months after surgery, the flap edge scar classified as Grade 0 had excellent apposition and rapid nerve regeneration. At 3 mm and 5 mm pupil diameters, there were significant differences in trefoil aberrations between the two groups(P<0.05), but no statistically significant differences were found in total higher order aberrations(HOAs), spherical aberrations or coma in any of the pupil size conditions(P>0.05).CONCLUSION: Flap edge scars classified as Grade 0 have excellent apposition and rapid nerve regeneration, and 120° side-cut angle flaps induce less trefoil aberrations after FS-LASIK.展开更多
基金Supported by the Science and Technology Program of Xi’an,China No.201805097YX5SF31(2)the Foundation of Shaanxi Province Key Research and Development Project (No.2018SF-216)。
文摘AIM: To investigate and evaluate healing patterns around flaps made with different side-cut angulations after femtosecond laser in situ keratomileusis(FS-LASIK).METHODS: Thirty-four patients(68 eyes) received a 90° side-cut(n=34) or a 120° side-cut flaps(n=34) made with a femtosecond laser. One day, 1 wk, 1 and 3 mo postoperatively, side-cut scar was evaluated under slit-lamp photography according to a new grading system(Grade 0=transparent scar, 1=faint healing opacity, and 2=evident healing opacity). In vivo corneal confocal microscopy and anterior segment optical coherence tomography(AS-OCT) were used to observe wound-healing patterns around flap margin in the two groups. Sirius Scheimpflug Analyzer was also used to analyze higher order aberrations 3 mo after surgery.RESULTS: There were no significant differences in flap wound-healing patterns at each follow up between the two groups(P>0.05). Three months after surgery, the flap edge scar classified as Grade 0 had excellent apposition and rapid nerve regeneration. At 3 mm and 5 mm pupil diameters, there were significant differences in trefoil aberrations between the two groups(P<0.05), but no statistically significant differences were found in total higher order aberrations(HOAs), spherical aberrations or coma in any of the pupil size conditions(P>0.05).CONCLUSION: Flap edge scars classified as Grade 0 have excellent apposition and rapid nerve regeneration, and 120° side-cut angle flaps induce less trefoil aberrations after FS-LASIK.
