Is endoscopic retrograde appendicitis therapy a better modality for acute uncomplicated appendicitis? A systematic review and metaanalysis

BACKGROUND Previous studies had shown endoscopic retrograde appendicitis therapy(ERAT)is an effective treatment for acute appendicitis.However,different studies reported conflicting outcomes regarding the effectiveness of ERAT in comparison with laparoscopic appendectomy(LA).AIM To compare the effectiveness of ERAT with LA.METHODS Randomized controlled trials(RCTs)and retrospective studies of ERAT for acute uncomplicated appendicitis were searched in PubMed,Cochrane Library,Web of Science,Embase database,China National Knowledge Infrastructure(CNKI),the WanFang Database,and Chinese Scientific Journals Database(VIP)from the establishment date to March 12021.Heterogeneity was assessed using the Isquared statistic.Pooled odds ratios(OR),weighted mean difference(WMD),and standard mean difference(SMD),with 95%confidence intervals(CI)were calculated through either fixed-effects or random-effects model.Sensitivity analysis was also performed.Publication bias was tested by Egger's test,and Begg’s test.The quality of included RCT were evaluated by the Jadad scale,while Newcastle-Ottawa scale is adopted for assessing the methodological quality of case-control studies.All statistical analysis was performed using Stata 15.1 statistical software.All statistical analysis was performed using Stata 15.1 statistical software.This study is registered with PROSPERO,CRD42021243955.RESULTS After screening,10 RCTs and 2 case-control studies were included in the current systematic review.Firstly,the length of hospitalizations[WMD=-1.15,95%CI:-1.99,-0.31;P=0.007]was shorter than LA group.Secondly,the level of postoperative CRP[WMD=-10.06,95%CI:(-17.39,-2.73);P=0.007],TNF-α[WMD=-7.70,95%CI:(-8.47,-6.93);P<0.001],and IL-6 Levels[WMD=-9.78,95%CI:(-10.69,-8.88);P<0.001;P<0.001]in ERAT group was significantly lower than LA group.Thirdly,ERAT group had a lower incidence of intestinal obstruction than LA group.[OR=0.19,95%CI:(0.05,0.79);P=0.020].Moreover,the quality of 10 RCTs were low with 0-3 Jadad scores,while the methodological quality of two case-control studies were fair with a score of 2(each).CONCLUSION Compared with LA,ERAT reduces operation time,the level of postoperative inflammation,and results in fewer complications and shorter recovery time,with preserving the appendix and its immune and biological functions.

Two-dimensional In_(2)Se_(3):A rising advanced material for ferroelectric data storage

Ferroelectric memory is a promising candidate for next-generation nonvolatile memory owing to its outstanding performance such as low power consump-tion,fast speed,and high endurance.However,the ferroelectricity of conven-tional ferroelectric materials will be eliminated by the depolarization field when the size drops to the nanometer scale.As a result,the miniaturization of ferroelectric devices was hindered,which makes ferroelectric memory unable to keep up with the development of integrated-circuit(IC)miniaturization.Recently,a two-dimensional(2D)In2Se3 was reported to maintain stable ferro-electricity at the ultrathin scale,which is expected to break through the bottle-neck of miniaturization.Soon,devices based on 2D In2Se3,including the ferroelectric field-effect transistor,ferroelectric channel transistor,synaptic fer-roelectric semiconductor junction,and ferroelectric memristor were demon-strated.However,a comprehensive understanding of the structures and the ferroelectric-switching mechanism of 2D In2Se3 is still lacking.Here,the atomic structures of different phases,the dynamic mechanism of ferroelectric switching,and the performance/functions of the latest devices of 2D In2Se3 are reviewed.Furthermore,the correlations among the structures,the properties,and the device performance are analyzed.Finally,several crucial problems or challenges and possible research directions are put forward.We hope that this review paper can provide timely knowledge and help for the research commu-nity to develop 2D In2Se3 based ferroelectric memory and computing technol-ogy for practical industrial applications.

改良型多介质土壤渗滤系统对甲鱼养殖废水的净化效果研究(英文)

目的:通过向多介质土壤渗滤系统(MSL)的土壤层添加污泥,研究改进后的系统对工厂化甲鱼养殖废水的处理效果,分析系统内微生物群落的变化,以期部分揭示其可能的作用机理。创新点:工厂化甲鱼养殖废水排放量日益增大,且水体氨氮含量较高。目前市场上缺乏针对甲鱼养殖废水的处理技术,MSL系统对该废水的处理也未有报道。本文在MSL系统的基础上进行改良,并将其应用于甲鱼养殖废水处理上,提出一套有效的甲鱼养殖废水处理技术,并对MSL系统内微生物群落结构进行了分析。方法:向4套MSL小试装置中分别添加0%、5%、10%和20%污泥,研究其对工厂化甲鱼养殖废水的净化效果。试验中水质指标测定均按国家标准方法进行,系统内微生物群落结构采用聚合酶链反应-变性梯度凝胶电泳(PCR-DGGE)法测定。结论:MSL系统可有效地处理工厂化甲鱼养殖废水,向系统中添加20%污泥后处理效果更佳。添加20%污泥的系统内具有较高的硝化类细菌多样性和都较多的生物量。

Mass transport phenomena in copper nanowires at high current density

当在 Cu 的典型故障失败的根原因相连，在 Cu 的 Electromigration 广泛地被调查了。在这研究，连接到 Au 电极的 Cu nanowires 被制作并且遵守了在 situ 传播电子显微镜学使用调查被直接电流导致的电镀物品迁居和热移动过程扫。我们观察不同集体运输机制的动态进化。大概 10 6A/ 厘米 2 和约 400 的温度的当前的密度 ????? 爠瑯牡獹楬楤杮?????????