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Multiple inflammatory pseudotumor formation after craniopharyngioma resection via an extended nasal endoscopic approach:A case report
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作者 Hao Wu yu-wei ding +3 位作者 Zheng-Cun Yan Min Wei Xiao-Dong Wang Heng-Zhu Zhang 《World Journal of Clinical Cases》 SCIE 2023年第31期7724-7731,共8页
BACKGROUND This report describes a case of intracranial multiple inflammatory pseudotumors(IP)after endoscopic resection of a craniopharyngioma,which is relatively rarely reported in the literature,and neurosurgeons s... BACKGROUND This report describes a case of intracranial multiple inflammatory pseudotumors(IP)after endoscopic resection of a craniopharyngioma,which is relatively rarely reported in the literature,and neurosurgeons should be aware of its existence.CASE SUMMARY Herein,we report the case of a 56-year-old man who developed decreased visual acuity and blurred vision without obvious cause or inducement on April 27,2020.To seek further treatment,he went to the Department of Neurosurgery,Clinical Medical College,Yangzhou University.After falling ill,there was no nausea,vomiting,limb convulsions,obvious disturbance of consciousness,speech disorders,cough,or persistent fever.The neurological examination findings were normal,and pituitary magnetic resonance imaging(MRI)revealed multiple nodules with abnormal signals in the sellar region.The diagnosis was craniopharyngioma.We performed total resection of the tumor via transnasal endoscopy,and the postoperative pathology suggested that the type of tumor was craniopharyngioma.Six months after the operation,the patient experienced sudden hearing loss in the right ear,tinnitus in both ears,and numbness on the right side of the face and head.Meanwhile,cranial MRI showed multiple IP.After steroid hormone and anti-inflammatory therapy,the above symptoms did not significantly improve.Finally,the patient's symptoms were well improved by surgery,and the postoperative pathological diagnosis was multiple IP.CONCLUSION Intracranial inflammatory pseudotumor is a benign disease with slow progression,but the clinical symptoms and imaging findings are not typical,there are no pathological findings,and the diagnosis is relatively difficult.Most of the cases are treated by surgical resection,and the prognosis is good after surgery. 展开更多
关键词 Multiple inflammatory pseudotumors CRANIOPHARYNGIOMA Treatment Brain ONCOLOGY Case report
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肺肉瘤样癌分子病理学与靶向治疗的研究进展 被引量:3
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作者 丁雨薇 唐秀珺 +3 位作者 程怡 朱柠 翁姗姗 袁瑛 《医学新知》 CAS 2021年第2期138-144,共7页
肺肉瘤样癌是指含有肉瘤或肉瘤样分化成分的非小细胞肺癌,其发病率占非小细胞肺癌总数的2%~3%。肺肉瘤样癌分化极差,具有高度侵袭性,对铂类为基础的化疗不敏感,治疗手段有限,一直是临床研究关注的重点和难点。现有研究发现肺肉瘤样癌中... 肺肉瘤样癌是指含有肉瘤或肉瘤样分化成分的非小细胞肺癌,其发病率占非小细胞肺癌总数的2%~3%。肺肉瘤样癌分化极差,具有高度侵袭性,对铂类为基础的化疗不敏感,治疗手段有限,一直是临床研究关注的重点和难点。现有研究发现肺肉瘤样癌中存在多种基因突变,包括TP53、EGFR、KRAS、MET和ALK等,以及高PD-L1阳性率,这些分子病理学特征有望成为肺肉瘤样癌靶向治疗的新希望。本文聚焦于肺肉瘤样癌分子病理学与靶向治疗研究进展作一综述。 展开更多
关键词 肺肉瘤样癌 靶向治疗 分子病理学 精准医学 免疫治疗
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Prevention and control of coronavirus disease 2019 in Grade-III Class-A hospitals outside of Wuhan
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作者 Jian-Wen Gu Hong-Jiang Wang +17 位作者 Quan-Xing Shi Yang Tao Feng Du Yun-Ming Li Yong-Xing Xu Li-Ping Jia He-Ming Yang Xiao-Tong Lou Ye-Tang Xiao Bin Shen Yu-Xia Cheng yu-wei ding Zheng Zhang Xin Guan Shi Wang Li Zhang Yu-Zhong Duan Chuang Nie 《Chinese Medical Journal》 SCIE CAS CSCD 2020年第16期1978-1980,共3页
Now,a novel coronavirus epidemic has posed a major threat to human health.Medical staff face a high risk of occupational exposure at very early stages of an epidemic.Once the medical staff are infected,it will greatly... Now,a novel coronavirus epidemic has posed a major threat to human health.Medical staff face a high risk of occupational exposure at very early stages of an epidemic.Once the medical staff are infected,it will greatly affect the“fighting capacity”of medical institutions,and help the virus spread within hospitals.These issues strongly suggest the critical role of hospital management,prevention,and control systems in the fight against infectious diseases. 展开更多
关键词 prevention OUTSIDE FIGHTING
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