AIM:To explore the efficacy of preoperative intravitreal bevacizumab(IVB) injection combined with Ahmed glaucoma valve(AGV) implantation in the treatment of neovascular glaucoma(NVG).METHODS:This retrospective study i...AIM:To explore the efficacy of preoperative intravitreal bevacizumab(IVB) injection combined with Ahmed glaucoma valve(AGV) implantation in the treatment of neovascular glaucoma(NVG).METHODS:This retrospective study included 35 eyes from 35 patients who underwent preoperative IVB and AGV implantation for treatment of NVG. Findings such as intraocular pressure(IOP) number of anti-glaucoma medications, visual acuity(VA), surgical success rates,and complications were recorded.RESULTS:AfterAGVimplantation,IOPwas18.2±4.0mmHg,15.5±3.3 mm Hg and 9.8±2.6 mm Hg at 6, 12 and 36 mo,significantly decreased compared with pre-IOP(P 【0.01).The number of anti-glaucoma medications was 0.9 ±0.5,0.8 ±0.9 and 0.8 ±0.6 at 6, 12 and 36 mo, significantly decreased compared to pre-treatment(P 【0.01). At last visit, there were 19 eyes with stable VA, 4 with VA improvement, 12 with diminished VA and 3 with complete loss light perception. There were 7 cases that failed during 3-year fellow up period. Cumulative probabilities of valve survival by Kaplan-Meier analysis were 82.9%,74.1% and 71.0% at 12, 24 and 36 mo, respectively. Cox stepwise regression analysis found that the survival time was significant associated with the pre-visual acuity 【2/400(P 【0.05). Post-operative complications occurred in 8eyes, of which hyphema presented in 2 eyes, choroidal effusion in 2 eyes.CONCLUSION:The procedure of preoperative IVB andAGV implantation should be one of treatments for NVG because of its safety and effectiveness.展开更多
In order to analysis the distribution characteristics of in-bore magnetic field for C-shaped armature electromagnetic railgun, a computational model considering dynamic contact pressure is established. By solving the ...In order to analysis the distribution characteristics of in-bore magnetic field for C-shaped armature electromagnetic railgun, a computational model considering dynamic contact pressure is established. By solving the dynamic equation, the in-bore motion characteristics of the armature are obtained. The distribution of current in the rail and armature is analyzed based on the magnetic diffusion equation and Ampere’s law. On this basis, three simulation models are proposed, which correspond to static state,motion state and motion state considering the velocity skin effect. The magnetic field of the investigated points along the central axes of the armature front end are obtained. The results show that, in static state,the peak magnetic flux density of each investigated point is greater than the other two states. Velocity skin effect leads to a decrease in peak magnetic flux density. The change of motion state has little influence on the peak magnetic flux density of the investigated point that far away from the armature. The calculated results can be used in the electromagnetic shielding design of intelligent ammunition.展开更多
文摘AIM:To explore the efficacy of preoperative intravitreal bevacizumab(IVB) injection combined with Ahmed glaucoma valve(AGV) implantation in the treatment of neovascular glaucoma(NVG).METHODS:This retrospective study included 35 eyes from 35 patients who underwent preoperative IVB and AGV implantation for treatment of NVG. Findings such as intraocular pressure(IOP) number of anti-glaucoma medications, visual acuity(VA), surgical success rates,and complications were recorded.RESULTS:AfterAGVimplantation,IOPwas18.2±4.0mmHg,15.5±3.3 mm Hg and 9.8±2.6 mm Hg at 6, 12 and 36 mo,significantly decreased compared with pre-IOP(P 【0.01).The number of anti-glaucoma medications was 0.9 ±0.5,0.8 ±0.9 and 0.8 ±0.6 at 6, 12 and 36 mo, significantly decreased compared to pre-treatment(P 【0.01). At last visit, there were 19 eyes with stable VA, 4 with VA improvement, 12 with diminished VA and 3 with complete loss light perception. There were 7 cases that failed during 3-year fellow up period. Cumulative probabilities of valve survival by Kaplan-Meier analysis were 82.9%,74.1% and 71.0% at 12, 24 and 36 mo, respectively. Cox stepwise regression analysis found that the survival time was significant associated with the pre-visual acuity 【2/400(P 【0.05). Post-operative complications occurred in 8eyes, of which hyphema presented in 2 eyes, choroidal effusion in 2 eyes.CONCLUSION:The procedure of preoperative IVB andAGV implantation should be one of treatments for NVG because of its safety and effectiveness.
基金supported by the Key Basic Research Projects of Basic Strengthening Plan under Grants 2017-JCJQ-ZD-004
文摘In order to analysis the distribution characteristics of in-bore magnetic field for C-shaped armature electromagnetic railgun, a computational model considering dynamic contact pressure is established. By solving the dynamic equation, the in-bore motion characteristics of the armature are obtained. The distribution of current in the rail and armature is analyzed based on the magnetic diffusion equation and Ampere’s law. On this basis, three simulation models are proposed, which correspond to static state,motion state and motion state considering the velocity skin effect. The magnetic field of the investigated points along the central axes of the armature front end are obtained. The results show that, in static state,the peak magnetic flux density of each investigated point is greater than the other two states. Velocity skin effect leads to a decrease in peak magnetic flux density. The change of motion state has little influence on the peak magnetic flux density of the investigated point that far away from the armature. The calculated results can be used in the electromagnetic shielding design of intelligent ammunition.
